Outcomes of preterm infants conceived with in vitro fertilization View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-02-05

AUTHORS

Kaashif Aqeeb Ahmad, Monica M Bennett, Polli Rayburn, C Andrew Combs, Reese H Clark, Veeral N Tolia

ABSTRACT

OBJECTIVES: To determine if there is increased risk of prematurity-related complications for in vitro fertilization (IVF)-conceived preterm infants compared to matched controls. STUDY DESIGN: Cohort study of 23-34 weeks' preterm infants from 329 US NICUs discharged from 2009 to 2016. Each IVF patient was matched to three controls. RESULTS: We identified 6,756 IVF-conceived preterm infants who were matched with 20,268 controls. IVF-conceived infants had no increase in non-respiratory morbidities but had significantly higher rates of bronchopulmonary dysplasia (8.4% vs 7%, p < 0.001) and significantly greater exposure to common chronic respiratory medications. CONCLUSIONS: In this large cohort of IVF-conceived preterm infants we found similar outcomes to controls with the exception of bronchopulmonary dysplasia and respiratory medication exposure. Further research is needed to explore the influence of in vitro fertilization on the development of neonatal respiratory disease. More... »

PAGES

1

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41372-019-0332-y

DOI

http://dx.doi.org/10.1038/s41372-019-0332-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111913676

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30723282


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