Genetic variants associated with patent ductus arteriosus in extremely preterm infants View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-03

AUTHORS

John M. Dagle, Kelli K. Ryckman, Cassandra N. Spracklen, Allison M. Momany, C. Michael Cotten, Joshua Levy, Grier P. Page, Edward F. Bell, Waldemar A. Carlo, Seetha Shankaran, Ronald N. Goldberg, Richard A. Ehrenkranz, Jon E. Tyson, Barbara J. Stoll, Jeffrey C. Murray

ABSTRACT

OBJECTIVE: Patent ductus arteriosus (PDA) is a commonly observed condition in preterm infants. Prior studies have suggested a role for genetics in determining spontaneous ductal closure. Using samples from a large neonatal cohort we tested the hypothesis that common genetic variations are associated with PDA in extremely preterm infants. STUDY DESIGN: Preterm infants (n = 1013) enrolled at NICHD Neonatal Research Network sites were phenotyped for PDA. DNA was genotyped for 1634 single nucleotide polymorphisms (SNPs) from candidate genes. Analyses were adjusted for ancestral eigenvalues and significant epidemiologic variables. RESULTS: SNPs in several genes were associated with the clinical diagnosis of PDA and with surgical ligation in extremely preterm neonates diagnosed with PDA (p < 0.01). None of the associations were significant after correction for multiple comparisons. CONCLUSION: We identified several common genetic variants associated with PDA. These findings may inform further studies on genetic risk factors for PDA in preterm infants. More... »

PAGES

401-408

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41372-018-0285-6

DOI

http://dx.doi.org/10.1038/s41372-018-0285-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1110374282

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30518802


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Iowa", 
          "id": "https://www.grid.ac/institutes/grid.214572.7", 
          "name": [
            "Department of Pediatrics, University of Iowa, Iowa City, IA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dagle", 
        "givenName": "John M.", 
        "id": "sg:person.01252365556.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252365556.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Iowa", 
          "id": "https://www.grid.ac/institutes/grid.214572.7", 
          "name": [
            "Department of Pediatrics, University of Iowa, Iowa City, IA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ryckman", 
        "givenName": "Kelli K.", 
        "id": "sg:person.01243153606.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243153606.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of North Carolina at Chapel Hill", 
          "id": "https://www.grid.ac/institutes/grid.10698.36", 
          "name": [
            "Department of Genetics, University of North Carolina, Chapel Hill, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Spracklen", 
        "givenName": "Cassandra N.", 
        "id": "sg:person.01204641130.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204641130.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Iowa", 
          "id": "https://www.grid.ac/institutes/grid.214572.7", 
          "name": [
            "Department of Pediatrics, University of Iowa, Iowa City, IA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Momany", 
        "givenName": "Allison M.", 
        "id": "sg:person.01036137626.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036137626.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Duke University", 
          "id": "https://www.grid.ac/institutes/grid.26009.3d", 
          "name": [
            "Department of Pediatrics, Duke University, Durham, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cotten", 
        "givenName": "C. Michael", 
        "id": "sg:person.0645411371.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645411371.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "RTI International", 
          "id": "https://www.grid.ac/institutes/grid.62562.35", 
          "name": [
            "Social, Statistical and Environmental Sciences Unit, RTI International, Research Triangle Park, Durham, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Levy", 
        "givenName": "Joshua", 
        "id": "sg:person.01016014520.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016014520.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "RTI International", 
          "id": "https://www.grid.ac/institutes/grid.62562.35", 
          "name": [
            "Social, Statistical and Environmental Sciences Unit, RTI International, Atlanta, GA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Page", 
        "givenName": "Grier P.", 
        "id": "sg:person.01206322060.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01206322060.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Iowa", 
          "id": "https://www.grid.ac/institutes/grid.214572.7", 
          "name": [
            "Department of Pediatrics, University of Iowa, Iowa City, IA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bell", 
        "givenName": "Edward F.", 
        "id": "sg:person.01137036602.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137036602.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Alabama at Birmingham", 
          "id": "https://www.grid.ac/institutes/grid.265892.2", 
          "name": [
            "Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Carlo", 
        "givenName": "Waldemar A.", 
        "id": "sg:person.012037431137.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012037431137.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Wayne State University", 
          "id": "https://www.grid.ac/institutes/grid.254444.7", 
          "name": [
            "Department of Pediatrics, Wayne State University, Detroit, MI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shankaran", 
        "givenName": "Seetha", 
        "id": "sg:person.01012205540.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012205540.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Duke University", 
          "id": "https://www.grid.ac/institutes/grid.26009.3d", 
          "name": [
            "Department of Pediatrics, Duke University, Durham, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Goldberg", 
        "givenName": "Ronald N.", 
        "id": "sg:person.01321506103.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321506103.80"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Yale University", 
          "id": "https://www.grid.ac/institutes/grid.47100.32", 
          "name": [
            "Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ehrenkranz", 
        "givenName": "Richard A.", 
        "id": "sg:person.01340447740.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340447740.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas Health Science Center at Houston", 
          "id": "https://www.grid.ac/institutes/grid.267308.8", 
          "name": [
            "Department of Pediatrics, University of Texas Medical School at Houston, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tyson", 
        "givenName": "Jon E.", 
        "id": "sg:person.015040754152.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015040754152.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pediatrics, Emory University School of Medicine, Children\u2019s Healthcare of Atlanta, Atlanta, GA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stoll", 
        "givenName": "Barbara J.", 
        "id": "sg:person.01004633061.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01004633061.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Iowa", 
          "id": "https://www.grid.ac/institutes/grid.214572.7", 
          "name": [
            "Department of Pediatrics, University of Iowa, Iowa City, IA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Murray", 
        "givenName": "Jeffrey C.", 
        "id": "sg:person.013736075012.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013736075012.20"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1161/circresaha.108.180661", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001396997"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circresaha.108.180661", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001396997"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1302/2046-3758.57.2000502", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002115294"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.99.23.3036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002508936"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.hlc.2014.01.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007554294"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1253/circj.cj-13-1029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008754754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.semperi.2015.09.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013536895"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.yexcr.2007.03.042", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014955639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jpeds.2012.12.097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015041528"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jpeds.2006.01.047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016080315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000101776", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016191469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000101776", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016191469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/519795", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019061180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa075819", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019183847"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/pr.111.004770", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020384555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.earlhumdev.2016.12.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022323073"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1167/iovs.14-14841", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024349847"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0108578", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024978349"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/pdr.0b013e3182294471", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025096592", 
          "https://doi.org/10.1203/pdr.0b013e3182294471"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/pdr.0b013e3182294471", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025096592", 
          "https://doi.org/10.1203/pdr.0b013e3182294471"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.105.541524", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025137433"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/sji.12094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026003534"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpheart.00838.2013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027191073"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jpeds.2015.03.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027602650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/01.pdr.0000088016.67117.39", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027740492", 
          "https://doi.org/10.1203/01.pdr.0000088016.67117.39"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/01.pdr.0000088016.67117.39", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027740492", 
          "https://doi.org/10.1203/01.pdr.0000088016.67117.39"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/pdr.0b013e3181ed8609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029415797", 
          "https://doi.org/10.1203/pdr.0b013e3181ed8609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/pdr.0b013e3181ed8609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029415797", 
          "https://doi.org/10.1203/pdr.0b013e3181ed8609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/jhg.2016.93", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030763140", 
          "https://doi.org/10.1038/jhg.2016.93"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0138114", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038570765"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jpeds.2014.09.052", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042932239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s2213-8587(16)00113-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042988083"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bjophthalmol-2016-308828", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043365349"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jpeds.2016.05.066", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045092187"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jpeds.2011.05.042", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045850622"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00431-016-2705-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047454960", 
          "https://doi.org/10.1007/s00431-016-2705-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00431-016-2830-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049736512", 
          "https://doi.org/10.1007/s00431-016-2830-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00431-016-2830-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049736512", 
          "https://doi.org/10.1007/s00431-016-2830-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/bjp.2008.36", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050628314"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature14177", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053003561", 
          "https://doi.org/10.1038/nature14177"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0035-1544948", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057333424"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0036-1593351", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057367276"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1542/peds.2008-0313", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067826912"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1542/peds.2008-1117", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067827094"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jpeds.2017.05.024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085910834"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1542/peds.2017-2533", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100471826"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11239-018-1762-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107880758", 
          "https://doi.org/10.1007/s11239-018-1762-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11239-018-1762-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107880758", 
          "https://doi.org/10.1007/s11239-018-1762-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11239-018-1762-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107880758", 
          "https://doi.org/10.1007/s11239-018-1762-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11239-018-1762-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107880758", 
          "https://doi.org/10.1007/s11239-018-1762-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11239-018-1762-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107880758", 
          "https://doi.org/10.1007/s11239-018-1762-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/nu10111582", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107894265"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/nu10111582", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107894265"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/s41467-018-06863-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107926132", 
          "https://doi.org/10.1038/s41467-018-06863-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/s41467-018-06863-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107926132", 
          "https://doi.org/10.1038/s41467-018-06863-1"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-03", 
    "datePublishedReg": "2019-03-01", 
    "description": "OBJECTIVE: Patent ductus arteriosus (PDA) is a commonly observed condition in preterm infants. Prior studies have suggested a role for genetics in determining spontaneous ductal closure. Using samples from a large neonatal cohort we tested the hypothesis that common genetic variations are associated with PDA in extremely preterm infants.\nSTUDY DESIGN: Preterm infants (n\u2009=\u20091013) enrolled at NICHD Neonatal Research Network sites were phenotyped for PDA. DNA was genotyped for 1634 single nucleotide polymorphisms (SNPs) from candidate genes. Analyses were adjusted for ancestral eigenvalues and significant epidemiologic variables.\nRESULTS: SNPs in several genes were associated with the clinical diagnosis of PDA and with surgical ligation in extremely preterm neonates diagnosed with PDA (p\u2009<\u20090.01). None of the associations were significant after correction for multiple comparisons.\nCONCLUSION: We identified several common genetic variants associated with PDA. These findings may inform further studies on genetic risk factors for PDA in preterm infants.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41372-018-0285-6", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2424042", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.5053715", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694140", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2424052", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694215", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694139", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694163", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2424041", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694144", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694218", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.5054233", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694141", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694169", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694168", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2424015", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.5054215", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.5053741", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694162", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2424020", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694198", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2691028", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.5475983", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2424011", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2543377", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694201", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694225", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694170", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694173", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694265", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694137", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694217", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2694164", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2424039", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1095220", 
        "issn": [
          "0743-8346", 
          "1476-5543"
        ], 
        "name": "Journal of Perinatology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "39"
      }
    ], 
    "name": "Genetic variants associated with patent ductus arteriosus in extremely preterm infants", 
    "pagination": "401-408", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "69831bfe844210782065c5ebb65dbcbb73a60d3167c4cc67128661dacdff0223"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30518802"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8501884"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41372-018-0285-6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1110374282"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41372-018-0285-6", 
      "https://app.dimensions.ai/details/publication/pub.1110374282"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:18", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000368_0000000368/records_78944_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s41372-018-0285-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41372-018-0285-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41372-018-0285-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41372-018-0285-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41372-018-0285-6'


 

This table displays all metadata directly associated to this object as RDF triples.

395 TRIPLES      21 PREDICATES      72 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41372-018-0285-6 schema:about anzsrc-for:06
2 anzsrc-for:0604
3 schema:author N78995096c8cc4a97babd632c477c82f4
4 schema:citation sg:pub.10.1007/s00431-016-2705-y
5 sg:pub.10.1007/s00431-016-2830-7
6 sg:pub.10.1007/s11239-018-1762-7
7 sg:pub.10.1038/jhg.2016.93
8 sg:pub.10.1038/nature14177
9 sg:pub.10.1038/s41467-018-06863-1
10 sg:pub.10.1203/01.pdr.0000088016.67117.39
11 sg:pub.10.1203/pdr.0b013e3181ed8609
12 sg:pub.10.1203/pdr.0b013e3182294471
13 https://doi.org/10.1016/j.earlhumdev.2016.12.008
14 https://doi.org/10.1016/j.hlc.2014.01.010
15 https://doi.org/10.1016/j.jpeds.2006.01.047
16 https://doi.org/10.1016/j.jpeds.2011.05.042
17 https://doi.org/10.1016/j.jpeds.2012.12.097
18 https://doi.org/10.1016/j.jpeds.2014.09.052
19 https://doi.org/10.1016/j.jpeds.2015.03.012
20 https://doi.org/10.1016/j.jpeds.2016.05.066
21 https://doi.org/10.1016/j.jpeds.2017.05.024
22 https://doi.org/10.1016/j.yexcr.2007.03.042
23 https://doi.org/10.1016/s2213-8587(16)00113-3
24 https://doi.org/10.1038/bjp.2008.36
25 https://doi.org/10.1053/j.semperi.2015.09.006
26 https://doi.org/10.1055/s-0035-1544948
27 https://doi.org/10.1055/s-0036-1593351
28 https://doi.org/10.1056/nejmoa075819
29 https://doi.org/10.1086/519795
30 https://doi.org/10.1111/sji.12094
31 https://doi.org/10.1124/pr.111.004770
32 https://doi.org/10.1136/bjophthalmol-2016-308828
33 https://doi.org/10.1152/ajpheart.00838.2013
34 https://doi.org/10.1159/000101776
35 https://doi.org/10.1161/01.cir.99.23.3036
36 https://doi.org/10.1161/circresaha.108.180661
37 https://doi.org/10.1161/circulationaha.105.541524
38 https://doi.org/10.1167/iovs.14-14841
39 https://doi.org/10.1253/circj.cj-13-1029
40 https://doi.org/10.1302/2046-3758.57.2000502
41 https://doi.org/10.1371/journal.pone.0108578
42 https://doi.org/10.1371/journal.pone.0138114
43 https://doi.org/10.1542/peds.2008-0313
44 https://doi.org/10.1542/peds.2008-1117
45 https://doi.org/10.1542/peds.2017-2533
46 https://doi.org/10.3390/nu10111582
47 schema:datePublished 2019-03
48 schema:datePublishedReg 2019-03-01
49 schema:description OBJECTIVE: Patent ductus arteriosus (PDA) is a commonly observed condition in preterm infants. Prior studies have suggested a role for genetics in determining spontaneous ductal closure. Using samples from a large neonatal cohort we tested the hypothesis that common genetic variations are associated with PDA in extremely preterm infants. STUDY DESIGN: Preterm infants (n = 1013) enrolled at NICHD Neonatal Research Network sites were phenotyped for PDA. DNA was genotyped for 1634 single nucleotide polymorphisms (SNPs) from candidate genes. Analyses were adjusted for ancestral eigenvalues and significant epidemiologic variables. RESULTS: SNPs in several genes were associated with the clinical diagnosis of PDA and with surgical ligation in extremely preterm neonates diagnosed with PDA (p < 0.01). None of the associations were significant after correction for multiple comparisons. CONCLUSION: We identified several common genetic variants associated with PDA. These findings may inform further studies on genetic risk factors for PDA in preterm infants.
50 schema:genre research_article
51 schema:inLanguage en
52 schema:isAccessibleForFree false
53 schema:isPartOf N02dcc717ab81403fb35477e6b0b9b9cf
54 N27fffda32373432a9362f3db487fed82
55 sg:journal.1095220
56 schema:name Genetic variants associated with patent ductus arteriosus in extremely preterm infants
57 schema:pagination 401-408
58 schema:productId N0572ccbe211b44c49c1a6501f67e0db6
59 N06257cef831a43648d6372272e8ddc19
60 N3c6c1653aca74b8abee5b5bc62cf60fe
61 N4ce95de898604fbe91e2028cfb9da707
62 Nf087e640dd1c49b3b291ff7d03324061
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1110374282
64 https://doi.org/10.1038/s41372-018-0285-6
65 schema:sdDatePublished 2019-04-11T13:18
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher N54bd46f30086495ea54c968037cd271f
68 schema:url https://www.nature.com/articles/s41372-018-0285-6
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N02dcc717ab81403fb35477e6b0b9b9cf schema:volumeNumber 39
73 rdf:type schema:PublicationVolume
74 N0572ccbe211b44c49c1a6501f67e0db6 schema:name dimensions_id
75 schema:value pub.1110374282
76 rdf:type schema:PropertyValue
77 N06257cef831a43648d6372272e8ddc19 schema:name pubmed_id
78 schema:value 30518802
79 rdf:type schema:PropertyValue
80 N0a0562e7d2e24100aed19d063b6c10ff rdf:first sg:person.01321506103.80
81 rdf:rest Nacc2e210340d4b69ab201c9b6363fe7a
82 N110d66479e3c40f0a0f6c340c336c93c rdf:first sg:person.01012205540.29
83 rdf:rest N0a0562e7d2e24100aed19d063b6c10ff
84 N179e6d03441141a3ac68ed5b0ce503c2 rdf:first sg:person.0645411371.06
85 rdf:rest N8d0db3f43003427f801b840930b815ae
86 N27fffda32373432a9362f3db487fed82 schema:issueNumber 3
87 rdf:type schema:PublicationIssue
88 N343e135e44314956ae583a8d6bbce92e rdf:first sg:person.01204641130.94
89 rdf:rest N839252edfcb1437d87703edaa9d47e2d
90 N3c6c1653aca74b8abee5b5bc62cf60fe schema:name readcube_id
91 schema:value 69831bfe844210782065c5ebb65dbcbb73a60d3167c4cc67128661dacdff0223
92 rdf:type schema:PropertyValue
93 N44bfb5b9ae1c416a9a5d96623e2ad818 rdf:first sg:person.01243153606.30
94 rdf:rest N343e135e44314956ae583a8d6bbce92e
95 N4ce95de898604fbe91e2028cfb9da707 schema:name nlm_unique_id
96 schema:value 8501884
97 rdf:type schema:PropertyValue
98 N54bd46f30086495ea54c968037cd271f schema:name Springer Nature - SN SciGraph project
99 rdf:type schema:Organization
100 N78995096c8cc4a97babd632c477c82f4 rdf:first sg:person.01252365556.40
101 rdf:rest N44bfb5b9ae1c416a9a5d96623e2ad818
102 N839252edfcb1437d87703edaa9d47e2d rdf:first sg:person.01036137626.14
103 rdf:rest N179e6d03441141a3ac68ed5b0ce503c2
104 N8cc004bd283d4f31ba3cb0a570567654 rdf:first sg:person.013736075012.20
105 rdf:rest rdf:nil
106 N8d0db3f43003427f801b840930b815ae rdf:first sg:person.01016014520.14
107 rdf:rest Nb1d11a04072b4e90b7da1c59412c5b72
108 Nacc2e210340d4b69ab201c9b6363fe7a rdf:first sg:person.01340447740.81
109 rdf:rest Nf5ae54ec4f064ae0b0ee66043f99388b
110 Nb1d11a04072b4e90b7da1c59412c5b72 rdf:first sg:person.01206322060.94
111 rdf:rest Nf2387a534bed428ba00fc91f255b574c
112 Nca81d7d56d624eb5830b4dc6e94b083e rdf:first sg:person.01004633061.34
113 rdf:rest N8cc004bd283d4f31ba3cb0a570567654
114 Neda3d74a266744ec95e5818cc18cf85f schema:name Department of Pediatrics, Emory University School of Medicine, Children’s Healthcare of Atlanta, Atlanta, GA, USA
115 rdf:type schema:Organization
116 Nf087e640dd1c49b3b291ff7d03324061 schema:name doi
117 schema:value 10.1038/s41372-018-0285-6
118 rdf:type schema:PropertyValue
119 Nf2387a534bed428ba00fc91f255b574c rdf:first sg:person.01137036602.37
120 rdf:rest Nf7cac5aa56b74b29a0e59bcadae5de1b
121 Nf5ae54ec4f064ae0b0ee66043f99388b rdf:first sg:person.015040754152.75
122 rdf:rest Nca81d7d56d624eb5830b4dc6e94b083e
123 Nf7cac5aa56b74b29a0e59bcadae5de1b rdf:first sg:person.012037431137.35
124 rdf:rest N110d66479e3c40f0a0f6c340c336c93c
125 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
126 schema:name Biological Sciences
127 rdf:type schema:DefinedTerm
128 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
129 schema:name Genetics
130 rdf:type schema:DefinedTerm
131 sg:grant.2424011 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
132 rdf:type schema:MonetaryGrant
133 sg:grant.2424015 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
134 rdf:type schema:MonetaryGrant
135 sg:grant.2424020 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
136 rdf:type schema:MonetaryGrant
137 sg:grant.2424039 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
138 rdf:type schema:MonetaryGrant
139 sg:grant.2424041 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
140 rdf:type schema:MonetaryGrant
141 sg:grant.2424042 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
142 rdf:type schema:MonetaryGrant
143 sg:grant.2424052 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
144 rdf:type schema:MonetaryGrant
145 sg:grant.2543377 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
146 rdf:type schema:MonetaryGrant
147 sg:grant.2691028 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
148 rdf:type schema:MonetaryGrant
149 sg:grant.2694137 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
150 rdf:type schema:MonetaryGrant
151 sg:grant.2694139 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
152 rdf:type schema:MonetaryGrant
153 sg:grant.2694140 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
154 rdf:type schema:MonetaryGrant
155 sg:grant.2694141 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
156 rdf:type schema:MonetaryGrant
157 sg:grant.2694144 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
158 rdf:type schema:MonetaryGrant
159 sg:grant.2694162 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
160 rdf:type schema:MonetaryGrant
161 sg:grant.2694163 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
162 rdf:type schema:MonetaryGrant
163 sg:grant.2694164 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
164 rdf:type schema:MonetaryGrant
165 sg:grant.2694168 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
166 rdf:type schema:MonetaryGrant
167 sg:grant.2694169 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
168 rdf:type schema:MonetaryGrant
169 sg:grant.2694170 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
170 rdf:type schema:MonetaryGrant
171 sg:grant.2694173 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
172 rdf:type schema:MonetaryGrant
173 sg:grant.2694198 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
174 rdf:type schema:MonetaryGrant
175 sg:grant.2694201 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
176 rdf:type schema:MonetaryGrant
177 sg:grant.2694215 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
178 rdf:type schema:MonetaryGrant
179 sg:grant.2694217 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
180 rdf:type schema:MonetaryGrant
181 sg:grant.2694218 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
182 rdf:type schema:MonetaryGrant
183 sg:grant.2694225 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
184 rdf:type schema:MonetaryGrant
185 sg:grant.2694265 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
186 rdf:type schema:MonetaryGrant
187 sg:grant.5053715 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
188 rdf:type schema:MonetaryGrant
189 sg:grant.5053741 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
190 rdf:type schema:MonetaryGrant
191 sg:grant.5054215 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
192 rdf:type schema:MonetaryGrant
193 sg:grant.5054233 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
194 rdf:type schema:MonetaryGrant
195 sg:grant.5475983 http://pending.schema.org/fundedItem sg:pub.10.1038/s41372-018-0285-6
196 rdf:type schema:MonetaryGrant
197 sg:journal.1095220 schema:issn 0743-8346
198 1476-5543
199 schema:name Journal of Perinatology
200 rdf:type schema:Periodical
201 sg:person.01004633061.34 schema:affiliation Neda3d74a266744ec95e5818cc18cf85f
202 schema:familyName Stoll
203 schema:givenName Barbara J.
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01004633061.34
205 rdf:type schema:Person
206 sg:person.01012205540.29 schema:affiliation https://www.grid.ac/institutes/grid.254444.7
207 schema:familyName Shankaran
208 schema:givenName Seetha
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012205540.29
210 rdf:type schema:Person
211 sg:person.01016014520.14 schema:affiliation https://www.grid.ac/institutes/grid.62562.35
212 schema:familyName Levy
213 schema:givenName Joshua
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016014520.14
215 rdf:type schema:Person
216 sg:person.01036137626.14 schema:affiliation https://www.grid.ac/institutes/grid.214572.7
217 schema:familyName Momany
218 schema:givenName Allison M.
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036137626.14
220 rdf:type schema:Person
221 sg:person.01137036602.37 schema:affiliation https://www.grid.ac/institutes/grid.214572.7
222 schema:familyName Bell
223 schema:givenName Edward F.
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137036602.37
225 rdf:type schema:Person
226 sg:person.012037431137.35 schema:affiliation https://www.grid.ac/institutes/grid.265892.2
227 schema:familyName Carlo
228 schema:givenName Waldemar A.
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012037431137.35
230 rdf:type schema:Person
231 sg:person.01204641130.94 schema:affiliation https://www.grid.ac/institutes/grid.10698.36
232 schema:familyName Spracklen
233 schema:givenName Cassandra N.
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204641130.94
235 rdf:type schema:Person
236 sg:person.01206322060.94 schema:affiliation https://www.grid.ac/institutes/grid.62562.35
237 schema:familyName Page
238 schema:givenName Grier P.
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01206322060.94
240 rdf:type schema:Person
241 sg:person.01243153606.30 schema:affiliation https://www.grid.ac/institutes/grid.214572.7
242 schema:familyName Ryckman
243 schema:givenName Kelli K.
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243153606.30
245 rdf:type schema:Person
246 sg:person.01252365556.40 schema:affiliation https://www.grid.ac/institutes/grid.214572.7
247 schema:familyName Dagle
248 schema:givenName John M.
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252365556.40
250 rdf:type schema:Person
251 sg:person.01321506103.80 schema:affiliation https://www.grid.ac/institutes/grid.26009.3d
252 schema:familyName Goldberg
253 schema:givenName Ronald N.
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321506103.80
255 rdf:type schema:Person
256 sg:person.01340447740.81 schema:affiliation https://www.grid.ac/institutes/grid.47100.32
257 schema:familyName Ehrenkranz
258 schema:givenName Richard A.
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340447740.81
260 rdf:type schema:Person
261 sg:person.013736075012.20 schema:affiliation https://www.grid.ac/institutes/grid.214572.7
262 schema:familyName Murray
263 schema:givenName Jeffrey C.
264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013736075012.20
265 rdf:type schema:Person
266 sg:person.015040754152.75 schema:affiliation https://www.grid.ac/institutes/grid.267308.8
267 schema:familyName Tyson
268 schema:givenName Jon E.
269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015040754152.75
270 rdf:type schema:Person
271 sg:person.0645411371.06 schema:affiliation https://www.grid.ac/institutes/grid.26009.3d
272 schema:familyName Cotten
273 schema:givenName C. Michael
274 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645411371.06
275 rdf:type schema:Person
276 sg:pub.10.1007/s00431-016-2705-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1047454960
277 https://doi.org/10.1007/s00431-016-2705-y
278 rdf:type schema:CreativeWork
279 sg:pub.10.1007/s00431-016-2830-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049736512
280 https://doi.org/10.1007/s00431-016-2830-7
281 rdf:type schema:CreativeWork
282 sg:pub.10.1007/s11239-018-1762-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107880758
283 https://doi.org/10.1007/s11239-018-1762-7
284 rdf:type schema:CreativeWork
285 sg:pub.10.1038/jhg.2016.93 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030763140
286 https://doi.org/10.1038/jhg.2016.93
287 rdf:type schema:CreativeWork
288 sg:pub.10.1038/nature14177 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053003561
289 https://doi.org/10.1038/nature14177
290 rdf:type schema:CreativeWork
291 sg:pub.10.1038/s41467-018-06863-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107926132
292 https://doi.org/10.1038/s41467-018-06863-1
293 rdf:type schema:CreativeWork
294 sg:pub.10.1203/01.pdr.0000088016.67117.39 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027740492
295 https://doi.org/10.1203/01.pdr.0000088016.67117.39
296 rdf:type schema:CreativeWork
297 sg:pub.10.1203/pdr.0b013e3181ed8609 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029415797
298 https://doi.org/10.1203/pdr.0b013e3181ed8609
299 rdf:type schema:CreativeWork
300 sg:pub.10.1203/pdr.0b013e3182294471 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025096592
301 https://doi.org/10.1203/pdr.0b013e3182294471
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1016/j.earlhumdev.2016.12.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022323073
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1016/j.hlc.2014.01.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007554294
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1016/j.jpeds.2006.01.047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016080315
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1016/j.jpeds.2011.05.042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045850622
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1016/j.jpeds.2012.12.097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015041528
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1016/j.jpeds.2014.09.052 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042932239
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1016/j.jpeds.2015.03.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027602650
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1016/j.jpeds.2016.05.066 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045092187
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1016/j.jpeds.2017.05.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085910834
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1016/j.yexcr.2007.03.042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014955639
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1016/s2213-8587(16)00113-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042988083
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1038/bjp.2008.36 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050628314
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1053/j.semperi.2015.09.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013536895
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1055/s-0035-1544948 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057333424
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1055/s-0036-1593351 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057367276
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1056/nejmoa075819 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019183847
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1086/519795 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019061180
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1111/sji.12094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026003534
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1124/pr.111.004770 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020384555
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1136/bjophthalmol-2016-308828 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043365349
342 rdf:type schema:CreativeWork
343 https://doi.org/10.1152/ajpheart.00838.2013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027191073
344 rdf:type schema:CreativeWork
345 https://doi.org/10.1159/000101776 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016191469
346 rdf:type schema:CreativeWork
347 https://doi.org/10.1161/01.cir.99.23.3036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002508936
348 rdf:type schema:CreativeWork
349 https://doi.org/10.1161/circresaha.108.180661 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001396997
350 rdf:type schema:CreativeWork
351 https://doi.org/10.1161/circulationaha.105.541524 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025137433
352 rdf:type schema:CreativeWork
353 https://doi.org/10.1167/iovs.14-14841 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024349847
354 rdf:type schema:CreativeWork
355 https://doi.org/10.1253/circj.cj-13-1029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008754754
356 rdf:type schema:CreativeWork
357 https://doi.org/10.1302/2046-3758.57.2000502 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002115294
358 rdf:type schema:CreativeWork
359 https://doi.org/10.1371/journal.pone.0108578 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024978349
360 rdf:type schema:CreativeWork
361 https://doi.org/10.1371/journal.pone.0138114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038570765
362 rdf:type schema:CreativeWork
363 https://doi.org/10.1542/peds.2008-0313 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067826912
364 rdf:type schema:CreativeWork
365 https://doi.org/10.1542/peds.2008-1117 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067827094
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1542/peds.2017-2533 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100471826
368 rdf:type schema:CreativeWork
369 https://doi.org/10.3390/nu10111582 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107894265
370 rdf:type schema:CreativeWork
371 https://www.grid.ac/institutes/grid.10698.36 schema:alternateName University of North Carolina at Chapel Hill
372 schema:name Department of Genetics, University of North Carolina, Chapel Hill, NC, USA
373 rdf:type schema:Organization
374 https://www.grid.ac/institutes/grid.214572.7 schema:alternateName University of Iowa
375 schema:name Department of Pediatrics, University of Iowa, Iowa City, IA, USA
376 rdf:type schema:Organization
377 https://www.grid.ac/institutes/grid.254444.7 schema:alternateName Wayne State University
378 schema:name Department of Pediatrics, Wayne State University, Detroit, MI, USA
379 rdf:type schema:Organization
380 https://www.grid.ac/institutes/grid.26009.3d schema:alternateName Duke University
381 schema:name Department of Pediatrics, Duke University, Durham, NC, USA
382 rdf:type schema:Organization
383 https://www.grid.ac/institutes/grid.265892.2 schema:alternateName University of Alabama at Birmingham
384 schema:name Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA
385 rdf:type schema:Organization
386 https://www.grid.ac/institutes/grid.267308.8 schema:alternateName The University of Texas Health Science Center at Houston
387 schema:name Department of Pediatrics, University of Texas Medical School at Houston, Houston, TX, USA
388 rdf:type schema:Organization
389 https://www.grid.ac/institutes/grid.47100.32 schema:alternateName Yale University
390 schema:name Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA
391 rdf:type schema:Organization
392 https://www.grid.ac/institutes/grid.62562.35 schema:alternateName RTI International
393 schema:name Social, Statistical and Environmental Sciences Unit, RTI International, Atlanta, GA, USA
394 Social, Statistical and Environmental Sciences Unit, RTI International, Research Triangle Park, Durham, NC, USA
395 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...