Photodynamic therapy guidelines for the management of oral leucoplakia. View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-06

AUTHORS

Qianming Chen, Hongxia Dan, Fan Tang, Jiongke Wang, Xiaoying Li, Junxin Cheng, Hang Zhao, Xin Zeng

ABSTRACT

With recent developments in photosensitizers and light delivery systems, topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) has become the fourth alternative therapeutic approach in the management of oral leucoplakia (OLK) due to its minimally invasive nature, efficacy, and low risk of systemic side effects and disfigurement. This report presents step-by-step guidelines for applying topical ALA-PDT in the management of OLK based on both the clinical experience of the authors and a systematic review of the current literature. Studies using protocols with standardized parameters and randomized clinical trials at multiple centres with adequate sample sizes and both interim and long-term follow-ups are needed before universally applicable guidelines can be produced in this field. More... »

PAGES

14

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41368-019-0047-0

DOI

http://dx.doi.org/10.1038/s41368-019-0047-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113355898

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30971683


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