The role of systemic inflammation linking maternal BMI to neurodevelopment in children View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-01

AUTHORS

Jelske W. van der Burg, Sarbattama Sen, Virginia R. Chomitz, Jaap C. Seidell, Alan Leviton, Olaf Dammann

ABSTRACT

Children of obese mothers are at increased risk of developmental adversities. Maternal obesity is linked to an inflammatory in utero environment, which, in turn, is associated with neurodevelopmental impairments in the offspring. This is an integrated mechanism review of animal and human literature related to the hypothesis that maternal obesity causes maternal and fetal inflammation, and that this inflammation adversely affects the neurodevelopment of children. We propose integrative models in which several aspects of inflammation are considered along the causative pathway linking maternal obesity with neurodevelopmental limitations. More... »

PAGES

3-12

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/pr.2015.179

    DOI

    http://dx.doi.org/10.1038/pr.2015.179

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1053511673

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/26375474


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