RNase III enzymes and the initiation of gene silencing View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-03

AUTHORS

Michelle A Carmell, Gregory J Hannon

ABSTRACT

Our understanding of RNA interference has been enhanced by new data concerning RNase III molecules. The role of Dicer has previously been established in RNAi as the originator of 22-mers characteristic of silencing phenomena. Recently, a related RNAse III enzyme, Drosha, has surfaced as another component of the RNAi pathway. In addition to biochemistry, protein structures have proven to be helpful in deciphering the enzymology of RNase III molecules. More... »

PAGES

214-218

Journal

TITLE

Nature Structural & Molecular Biology

ISSUE

3

VOLUME

11

From Grant

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nsmb729

    DOI

    http://dx.doi.org/10.1038/nsmb729

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1015922363

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/14983173


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