Genome-wide nucleosome positioning during embryonic stem cell development View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-11

AUTHORS

Vladimir B Teif, Yevhen Vainshtein, Maïwen Caudron-Herger, Jan-Philipp Mallm, Caroline Marth, Thomas Höfer, Karsten Rippe

ABSTRACT

We determined genome-wide nucleosome occupancies in mouse embryonic stem cells and their neural progenitor and embryonic fibroblast counterparts to assess features associated with nucleosome positioning during lineage commitment. Cell-type- and protein-specific binding preferences of transcription factors to sites with either low (Myc, Klf4 and Zfx) or high (Nanog, Oct4 and Sox2) nucleosome occupancy as well as complex patterns for CTCF were identified. Nucleosome-depleted regions around transcription start and transcription termination sites were broad and more pronounced for active genes, with distinct patterns for promoters classified according to CpG content or histone methylation marks. Throughout the genome, nucleosome occupancy was correlated with certain histone methylation or acetylation modifications. In addition, the average nucleosome repeat length increased during differentiation by 5-7 base pairs, with local variations for specific regions. Our results reveal regulatory mechanisms of cell differentiation that involve nucleosome repositioning. More... »

PAGES

1185

References to SciGraph publications

  • 2006-10. Nucleosome positions predicted through comparative genomics in NATURE GENETICS
  • 2008-11. Model-based Analysis of ChIP-Seq (MACS) in GENOME BIOLOGY
  • 2009-08. Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2012-08. Chromatin organization is a major influence on regional mutation rates in human cancer cells in NATURE
  • 2009-03. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome in GENOME BIOLOGY
  • 2006-02. Role of linker histone in chromatin structure and function: H1 stoichiometry and nucleosome repeat length in CHROMOSOME RESEARCH
  • 2011-06. Determinants of nucleosome organization in primary human cells in NATURE
  • 2009-01. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources in NATURE PROTOCOLS
  • 2011-10-30. Control of Drosophila endocycles by E2F and CRL4CDT2 in NATURE
  • 2011-07. CTCF-mediated functional chromatin interactome in pluripotent cells in NATURE GENETICS
  • 2011-06. The nucleosome map of the mammalian liver in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2007-08. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells in NATURE
  • 2012-03-01. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks in NATURE PROTOCOLS
  • 2009-03. The DNA-encoded nucleosome organization of a eukaryotic genome in NATURE
  • 2008-05-15. Nucleosome organization in the Drosophila genome in NATURE
  • 2012. Genome-Wide Approaches to Determining Nucleosome Occupancy in Metazoans Using MNase-Seq in CHROMATIN REMODELING
  • 2012-08. A map of the cis-regulatory sequences in the mouse genome in NATURE
  • 2010-10. Differential expression analysis for sequence count data in GENOME BIOLOGY
  • 2006-08. A genomic code for nucleosome positioning in NATURE
  • 2010-05. Widespread remodeling of mid-coding sequence nucleosomes by Isw1 in GENOME BIOLOGY
  • 2012-04. Metazoan promoters: emerging characteristics and insights into transcriptional regulation in NATURE REVIEWS GENETICS
  • 2011-06. Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nsmb.2419

    DOI

    http://dx.doi.org/10.1038/nsmb.2419

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1011038243

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/23085715


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