Architecture of the RNA polymerase II preinitiation complex and mechanism of ATP-dependent promoter opening View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-07-01

AUTHORS

Sebastian Grünberg, Linda Warfield, Steven Hahn

ABSTRACT

The general transcription factors TFIIE and TFIIH subunit Ssl2/XPB function in the transition of the preinitiation complex (PIC) to the open polymerase II (Pol II) complex. Efforts to localize TFIIE and Ssl2 in the yeast PIC now reveal crucial roles for the three TFIIE winged-helix domains and for Ssl2 in promoting DNA strand separation. More... »

PAGES

788-796

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nsmb.2334

DOI

http://dx.doi.org/10.1038/nsmb.2334

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003871257

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22751016


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