Ontology type: schema:ScholarlyArticle Open Access: True
2010-08-29
AUTHORSKyle M Miller, Jorrit V Tjeertes, Julia Coates, Gaëlle Legube, Sophie E Polo, Sébastien Britton, Stephen P Jackson
ABSTRACTHow changes in chromatin can modulate the repair pathway of DNA double-strand breaks is now investigated. The work shows that histone deacetylases HDAC1 and HDAC2 are recruited to sites of DNA damage, where they mediate the removal of H3K56 acetyl marks, and their activity is important for repair via non-homologous end-joining. More... »
PAGES1144-1151
http://scigraph.springernature.com/pub.10.1038/nsmb.1899
DOIhttp://dx.doi.org/10.1038/nsmb.1899
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/20802485
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