Accessibility of the Drosophila genome discriminates PcG repression, H4K16 acetylation and replication timing View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-06-20

AUTHORS

Oliver Bell, Michaela Schwaiger, Edward J Oakeley, Florian Lienert, Christian Beisel, Michael B Stadler, Dirk Schübeler

ABSTRACT

Accessibility may play a key regulatory role affecting factors that bind to or target DNA. Using accessibility to DNA methyltransferases, the genome-wide profile of DNA accessibility in Drosophila melanogaster is presented and analyzed, indicating correlations with PcG repression, H4K16 acetylation and replication initiation.

PAGES

894-900

References to SciGraph publications

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  • 2006-06-21. Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays in NATURE METHODS
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  • 2004-07. Chromatin regulates origin activity in Drosophila follicle cells in NATURE
  • 2008-10-19. A model for transmission of the H3K27me3 epigenetic mark in NATURE CELL BIOLOGY
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  • 2007-11-25. Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells in NATURE CELL BIOLOGY
  • 2009-03-04. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome in GENOME BIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nsmb.1825

    DOI

    http://dx.doi.org/10.1038/nsmb.1825

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1023608561

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20562853


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