The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1997-09

AUTHORS

Giovanna Musco, Abdelhakim Kharrat, Gunter Stier, Franca Fraternali, Toby J. Gibson, Michael Nilges, Annalisa Pastore

ABSTRACT

The structure and dynamics of the first KH domain of FMR1 — the protein responsible for fragile X syndrome — reveal that an exposed loop is highly flexible despite containing a GxxG motif that is well conserved throughout the KH family. We suggest that this region provides a putative binding surface for RNA recognition. More... »

PAGES

712-716

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nsb0997-712

DOI

http://dx.doi.org/10.1038/nsb0997-712

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012365395

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9302998


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