Connective tissue diseases: Mitochondria drive NETosis and inflammation in SLE View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-04

AUTHORS

Eric Boilard, Paul R. Fortin

ABSTRACT

Mitochondria are the powerhouses of the cell, providing energy through oxidative respiration. Possibly owing to their similarities with bacteria, however, mitochondria extruded from cells promote inflammation. New research demonstrates that in systemic lupus erythematosus, mitochondrial respiration is critical in neutrophil extracellular trap formation, and that mitochondria released by neutrophils induce inflammatory cytokine production. More... »

PAGES

195-196

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nrrheum.2016.24

DOI

http://dx.doi.org/10.1038/nrrheum.2016.24

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011224214

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26935279


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