Neuroprognostication of hypoxic-ischaemic coma in the therapeutic hypothermia era View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-04

AUTHORS

David M. Greer, Eric S. Rosenthal, Ona Wu

ABSTRACT

Neurological prognostication after cardiac arrest has always been challenging, and has become even more so since the advent of therapeutic hypothermia (TH) in the early 2000s. Studies in this field are prone to substantial biases--most importantly, the self-fulfilling prophecy of early withdrawal of life-sustaining therapies--and physicians must be aware of these limitations when evaluating individual patients. TH mandates sedation and prolongs drug metabolism, and delayed neuronal recovery is possible after cardiac arrest with or without hypothermia treatment; thus, the clinician must allow an adequate observation period to assess for delayed recovery. Exciting advances have been made in clinical evaluation, electrophysiology, chemical biomarkers and neuroimaging, providing insights into the underlying pathophysiological mechanisms of injury, as well as prognosis. Some clinical features, such as pupillary reactivity, continue to provide robust information about prognosis, and EEG patterns, such as reactivity and continuity, seem promising as prognostic indicators. Evoked potential information is likely to remain a reliable prognostic tool in TH-treated patients, whereas traditional serum biomarkers, such as neuron-specific enolase, may be less reliable. Advanced neuroimaging techniques, particularly those utilizing MRI, hold great promise for the future. Clinicians should continue to use all the available tools to provide accurate prognostic advice to patients after cardiac arrest. More... »

PAGES

190-203

References to SciGraph publications

  • 2009-09. Serum Neuron Specific Enolase and Malondialdehyde in Patients After Out-Of-Hospital Cardiac Arrest in CELLULAR AND MOLECULAR NEUROBIOLOGY
  • 2005-12. Observations on comatose survivors of cardiopulmonary resuscitation with generalized myoclonus in BMC NEUROLOGY
  • 2010-03. Oseltamivir dosing with haemofiltration in CRITICAL CARE
  • 2006-06. Amplitude-integrated EEG (aEEG) predicts outcome after cardiac arrest and induced hypothermia in INTENSIVE CARE MEDICINE
  • 2005-04. Anoxic-ischemic encephalopathy in NEUROCRITICAL CARE
  • 2009-12. Early EEG Monitoring for Detecting Postanoxic Status Epilepticus during Therapeutic Hypothermia: A Pilot Study in NEUROCRITICAL CARE
  • 2004-06. MRI in anoxic brain injury in NEUROCRITICAL CARE
  • 2013-10. A Cerebral Recovery Index (CRI) for early prognosis in patients after cardiac arrest in CRITICAL CARE
  • 2011-02. Short-Term Outcome Prediction by Electroencephalographic Features in Children Treated with Therapeutic Hypothermia After Cardiac Arrest in NEUROCRITICAL CARE
  • 2009-04. Changes in S-100 protein serum levels in survivors of out-of-hospital cardiac arrest treated with mild therapeutic hypothermia: a prospective, observational study in CRITICAL CARE
  • 2012-02. Frequency and Timing of Nonconvulsive Status Epilepticus in Comatose Post-Cardiac Arrest Subjects Treated with Hypothermia in NEUROCRITICAL CARE
  • 2009-02. The strong ion gap and outcome after cardiac arrest in patients treated with therapeutic hypothermia: a retrospective study in INTENSIVE CARE MEDICINE
  • 2012-12. Prognostic Performance of Diffusion-Weighted MRI Combined with NSE in Comatose Cardiac Arrest Survivors Treated with Mild Hypothermia in NEUROCRITICAL CARE
  • 1991-07. Prognostic significance of early intracranial and cerebral perfusion pressures in post-cardiac arrest anoxic coma in INTENSIVE CARE MEDICINE
  • 2012-12. Pain-related somatosensory evoked potentials and functional brain magnetic resonance in the evaluation of neurologic recovery after cardiac arrest: a case study of three patients in SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE
  • 2010-10. Prognostic value of continuous EEG monitoring during therapeutic hypothermia after cardiac arrest in CRITICAL CARE
  • 1978-12. Neurone-specific enolase is a molecular marker for peripheral and central neuroendocrine cells in NATURE
  • 2013-10. Prognostication of neurologic outcome in cardiac arrest patients after mild therapeutic hypothermia: a meta-analysis of the current literature in INTENSIVE CARE MEDICINE
  • 2011-02. Serial MRI Changes in Comatose Cardiac Arrest Patients in NEUROCRITICAL CARE
  • 2009-10. Changes in serum creatinine in the first 24 hours after cardiac arrest indicate prognosis: an observational cohort study in CRITICAL CARE
  • 2013-12. A structured approach to neurologic prognostication in clinical cardiac arrest trials in SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE
  • 2010-02. The bispectral index and suppression ratio are very early predictors of neurological outcome during therapeutic hypothermia after cardiac arrest in INTENSIVE CARE MEDICINE
  • 2001-08. Time-dependency of sensory evoked potentials in comatose cardiac arrest survivors in INTENSIVE CARE MEDICINE
  • 2011-12. Serum neuron-specific enolase as predictor of outcome in comatose cardiac-arrest survivors: a prospective cohort study in BMC CARDIOVASCULAR DISORDERS
  • 2012-10. Clinical MRI Interpretation for Outcome Prediction in Cardiac Arrest in NEUROCRITICAL CARE
  • 2013-12. The prognostic value of gray-white-matter ratio in cardiac arrest patients treated with hypothermia in SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE
  • 2011-08. Sedation Confounds Outcome Prediction in Cardiac Arrest Survivors Treated with Hypothermia in NEUROCRITICAL CARE
  • 2013-10. Serum Neuron-Specific Enolase Levels from the Same Patients Differ Between Laboratories: Assessment of a Prospective Post-cardiac Arrest Cohort in NEUROCRITICAL CARE
  • 2010-04. Mild therapeutic hypothermia alters neuron specific enolase as an outcome predictor after resuscitation: 97 prospective hypothermia patients compared to 133 historical non-hypothermia patients in CRITICAL CARE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrneurol.2014.36

    DOI

    http://dx.doi.org/10.1038/nrneurol.2014.36

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1015663821

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/24614515


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