Molecular mechanisms of antibiotic resistance View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-01

AUTHORS

Jessica M. A. Blair, Mark A. Webber, Alison J. Baylay, David O. Ogbolu, Laura J. V. Piddock

ABSTRACT

Antibiotic-resistant bacteria that are difficult or impossible to treat are becoming increasingly common and are causing a global health crisis. Antibiotic resistance is encoded by several genes, many of which can transfer between bacteria. New resistance mechanisms are constantly being described, and new genes and vectors of transmission are identified on a regular basis. This article reviews recent advances in our understanding of the mechanisms by which bacteria are either intrinsically resistant or acquire resistance to antibiotics, including the prevention of access to drug targets, changes in the structure and protection of antibiotic targets and the direct modification or inactivation of antibiotics. More... »

PAGES

42-51

References to SciGraph publications

  • 2006-09. Crystal structures of a multidrug transporter reveal a functionally rotating mechanism in NATURE
  • 2013-12. The crystal structure of multidrug-resistance regulator RamR with multiple drugs in NATURE COMMUNICATIONS
  • 2012-12. Effects of indole on drug resistance and virulence of Salmonella enterica serovar Typhimurium revealed by genome-wide analyses in GUT PATHOGENS
  • 2012-11. Spread of an OmpK36-modified ST15 Klebsiella pneumoniae variant during an outbreak involving multiple carbapenem-resistant Enterobacteriaceae species and clones in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
  • 2011-09. Antibiotic resistance is ancient in NATURE
  • 2010-08. Integrative and conjugative elements: mosaic mobile genetic elements enabling dynamic lateral gene flow in NATURE REVIEWS MICROBIOLOGY
  • 2013-03. The Expression of ABC Efflux Pump, Rv1217c–Rv1218c, and Its Association with Multidrug Resistance of Mycobacterium tuberculosis in China in CURRENT MICROBIOLOGY
  • 2014-05. Structure of the AcrAB–TolC multidrug efflux pump in NATURE
  • 2011-12. Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket in NATURE
  • 2013-06. Crystal structure of AcrB complexed with linezolid at 3.5 Å resolution in JOURNAL OF STRUCTURAL AND FUNCTIONAL GENOMICS
  • 2011-12. Whole genome analysis of linezolid resistance in Streptococcus pneumoniae reveals resistance and compensatory mutations in BMC GENOMICS
  • 2011-02. Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli in NATURE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrmicro3380

    DOI

    http://dx.doi.org/10.1038/nrmicro3380

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1047623025

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/25435309


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical Microbiology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Anti-Bacterial Agents", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Bacteria", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Drug Resistance, Bacterial", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Signal Transduction", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "University of Birmingham", 
              "id": "https://www.grid.ac/institutes/grid.6572.6", 
              "name": [
                "Antimicrobials Research Group, School of Immunity and Infection, Institute for Microbiology and Infection, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Blair", 
            "givenName": "Jessica M. A.", 
            "id": "sg:person.0670513324.70", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0670513324.70"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Birmingham", 
              "id": "https://www.grid.ac/institutes/grid.6572.6", 
              "name": [
                "Antimicrobials Research Group, School of Immunity and Infection, Institute for Microbiology and Infection, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Webber", 
            "givenName": "Mark A.", 
            "id": "sg:person.01220046325.39", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220046325.39"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Birmingham", 
              "id": "https://www.grid.ac/institutes/grid.6572.6", 
              "name": [
                "Antimicrobials Research Group, School of Immunity and Infection, Institute for Microbiology and Infection, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Baylay", 
            "givenName": "Alison J.", 
            "id": "sg:person.01040166173.37", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01040166173.37"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Birmingham", 
              "id": "https://www.grid.ac/institutes/grid.6572.6", 
              "name": [
                "Antimicrobials Research Group, School of Immunity and Infection, Institute for Microbiology and Infection, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ogbolu", 
            "givenName": "David O.", 
            "id": "sg:person.0665070460.43", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665070460.43"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Birmingham", 
              "id": "https://www.grid.ac/institutes/grid.6572.6", 
              "name": [
                "Antimicrobials Research Group, School of Immunity and Infection, Institute for Microbiology and Infection, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Piddock", 
            "givenName": "Laura J. V.", 
            "id": "sg:person.0626621343.92", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626621343.92"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1128/jb.01517-09", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000865038"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dks373", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000986896"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1757-4749-4-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001041264", 
              "https://doi.org/10.1186/1757-4749-4-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ijmm.2013.02.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001131148"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1473-3099(11)70059-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002265687"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dkt540", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002287073"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1469-0691.2011.03715.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002839353"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.44.10.2861-2864.2000", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002851532"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.01477-07", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003017407"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature10388", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004674718", 
              "https://doi.org/10.1038/nature10388"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/324626", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004706151"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1473-3099(12)70317-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005577038"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1179/joc.2011.23.5.263", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005876828"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jmb.2009.02.048", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006412150"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1473-3099(11)70126-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008242137"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.44.6.1549-1555.2000", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008670270"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/cmr.00001-07", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008817892"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m111.246595", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008829637"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/jb.06582-11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009293241"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.02005-12", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009840115"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1310333110", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009909042"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.01743-12", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010529944"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.00284-09", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011082453"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/jb.183.13.3890-3902.2001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011170777"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev-micro-092412-155718", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011255487"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c0cc05111j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011607095"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ijantimicag.2012.08.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011738165"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pro.2273", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012120238"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2217/fmb.12.130", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013438110"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/jb.00565-13", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014496387"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/jcm.01773-10", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015385487"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1220761", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015606282"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/cmr.00043-12", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016255794"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.00809-12", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017567560"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.03110-14", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017573025"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1067/mic.2003.11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017983536"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1067/mic.2003.11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017983536"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature13205", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018733330", 
              "https://doi.org/10.1038/nature13205"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1574-6976.2011.00268.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018812640"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.tim.2011.09.005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018883000"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.48.6.2292-2294.2004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018911010"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1114944109", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018953235"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3389/fmicb.2013.00138", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019231953"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1179/1973947813y.0000000075", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020231250"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0051053", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020495072"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2958.2004.04449.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020880594"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.00131-06", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021473563"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/jcm.00847-13", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021539863"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/jcm.01244-13", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022196805"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.49.10.4390-4392.2005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022393691"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrmicro2382", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022443334", 
              "https://doi.org/10.1038/nrmicro2382"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrmicro2382", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022443334", 
              "https://doi.org/10.1038/nrmicro2382"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3201/eid1704.101009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022816510"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.gene.2012.02.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022832264"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ncomms3078", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022876536", 
              "https://doi.org/10.1038/ncomms3078"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10096-012-1665-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022890580", 
              "https://doi.org/10.1007/s10096-012-1665-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.00175-10", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022997111"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.01473-13", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023429384"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dkq463", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023510883"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m111.226936", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023532527"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00284-012-0215-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023842442", 
              "https://doi.org/10.1007/s00284-012-0215-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pro.2424", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023903314"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.01480-13", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024206929"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/1040841x.2012.691460", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024653201"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.05760-11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024760487"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/cmr.19.2.382-402.2006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025712748"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10969-013-9154-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026172598", 
              "https://doi.org/10.1007/s10969-013-9154-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10969-013-9154-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026172598", 
              "https://doi.org/10.1007/s10969-013-9154-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1218348109", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026749184"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1099/jmm.0.052555-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027023216"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.05870-11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027594543"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.01152-09", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027900306"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1469-0691.2007.01857.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028814910"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2958.2008.06424.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029023953"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dkt044", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029058116"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0900693106", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029780465"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.00906-09", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030340035"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.48.5.1630-1639.2004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030557673"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1574-6968.2004.tb09766.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030714777"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1574-6968.2004.tb09766.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030714777"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.06142-11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031265626"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dkt341", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031576615"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.00580-10", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031577358"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.05441-11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031937922"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.meegid.2012.02.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031962958"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1517/14656566.2013.763030", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032333627"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mbio.00446-12", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032807575"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.46.9.3045-3049.2002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033656859"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.00242-10", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033746892"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1592/phco.30.12.1279", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033967985"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.45.5.1550-1552.2001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034108055"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.49.1.161-169.2005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035149545"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/mmi.12211", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035627979"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.2013.280695", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036120723"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.00079-11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036714486"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0071151", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037163085"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.45.12.3595-3598.2001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037807721"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3389/fmicb.2013.00212", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038173588"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2164-12-512", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038210304", 
              "https://doi.org/10.1186/1471-2164-12-512"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.00084-08", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039014870"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.addr.2005.04.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039058702"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/prot.24185", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039215910"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bmcl.2007.07.072", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039289854"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dku140", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040161296"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.02686-14", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040409189"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/cmr.05035-11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040580528"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature05076", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040864737", 
              "https://doi.org/10.1038/nature05076"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature05076", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040864737", 
              "https://doi.org/10.1038/nature05076"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature05076", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040864737", 
              "https://doi.org/10.1038/nature05076"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.01004-09", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041085747"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.00848-12", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041149291"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.00313-12", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041455740"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.06112-11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042444311"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.05391-11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042485925"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0034953", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042503168"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0082814", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042587583"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature09743", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042954496", 
              "https://doi.org/10.1038/nature09743"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dkq431", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043063047"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1099/mic.0.045757-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043422263"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mbio.00281-13", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043557265"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.ppat.1000944", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043789254"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ijantimicag.2012.04.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044369175"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.45.4.1151-1161.2001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044793518"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dkr431", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044944688"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature10641", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045294582", 
              "https://doi.org/10.1038/nature10641"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/prot.24163", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045563939"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dkt355", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045723454"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.00187-11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046649668"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1473-3099(10)70143-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047068088"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aem.07320-11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047509330"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dks084", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047590849"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dkt078", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047800478"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1469-0691.2007.01867.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048048999"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3389/fmicb.2013.00213", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048052896"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1402358111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048554368"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.biochem.78.082907.145923", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049536673"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dks357", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049960340"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ijantimicag.2012.10.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050160622"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.32.11.1680", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050717946"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.48.12.4793-4799.2004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050882193"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dkn396", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052167149"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jac/dkt092", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053190655"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/bi060320g", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055201819"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/bi060320g", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055201819"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/mdr.2006.12.223", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059297514"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/mdr.2012.0250", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059297943"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1099/jmm.0.045799-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060391744"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/15680266113136660220", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069194717"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2741/1075", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1070913383"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2807/1560-7917.es2013.18.31.20547", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1070926095"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1079528589", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.40.10.2380", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1082989036"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aac.41.10.2067", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083159784"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2015-01", 
        "datePublishedReg": "2015-01-01", 
        "description": "Antibiotic-resistant bacteria that are difficult or impossible to treat are becoming increasingly common and are causing a global health crisis. Antibiotic resistance is encoded by several genes, many of which can transfer between bacteria. New resistance mechanisms are constantly being described, and new genes and vectors of transmission are identified on a regular basis. This article reviews recent advances in our understanding of the mechanisms by which bacteria are either intrinsically resistant or acquire resistance to antibiotics, including the prevention of access to drug targets, changes in the structure and protection of antibiotic targets and the direct modification or inactivation of antibiotics. ", 
        "genre": "research_article", 
        "id": "sg:pub.10.1038/nrmicro3380", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2760163", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1032854", 
            "issn": [
              "1740-1526", 
              "1740-1534"
            ], 
            "name": "Nature Reviews Microbiology", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "13"
          }
        ], 
        "name": "Molecular mechanisms of antibiotic resistance", 
        "pagination": "42-51", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "e2dd0db81b54817353ea5e68a53d0e6b6cb11d90df0ba2d17ca05f4369452e37"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "25435309"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "101190261"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/nrmicro3380"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1047623025"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/nrmicro3380", 
          "https://app.dimensions.ai/details/publication/pub.1047623025"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T01:47", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8700_00000426.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://www.nature.com/articles/nrmicro3380"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nrmicro3380'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nrmicro3380'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nrmicro3380'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nrmicro3380'


     

    This table displays all metadata directly associated to this object as RDF triples.

    564 TRIPLES      21 PREDICATES      179 URIs      25 LITERALS      13 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/nrmicro3380 schema:about N2a43c2d0e66d4789b39f5f6731731d49
    2 Na15832dbb99e4a7b82ba1d3502c9300a
    3 Ncb057b83e97741d9bf0f39ee3812be93
    4 Ne2ea35b77aa54752a81c7e84a852ee3c
    5 anzsrc-for:11
    6 anzsrc-for:1108
    7 schema:author N4eb5b84ca907497d8137c46a3febfb50
    8 schema:citation sg:pub.10.1007/s00284-012-0215-3
    9 sg:pub.10.1007/s10096-012-1665-z
    10 sg:pub.10.1007/s10969-013-9154-x
    11 sg:pub.10.1038/nature05076
    12 sg:pub.10.1038/nature09743
    13 sg:pub.10.1038/nature10388
    14 sg:pub.10.1038/nature10641
    15 sg:pub.10.1038/nature13205
    16 sg:pub.10.1038/ncomms3078
    17 sg:pub.10.1038/nrmicro2382
    18 sg:pub.10.1186/1471-2164-12-512
    19 sg:pub.10.1186/1757-4749-4-5
    20 https://app.dimensions.ai/details/publication/pub.1079528589
    21 https://doi.org/10.1001/jama.2013.280695
    22 https://doi.org/10.1002/pro.2273
    23 https://doi.org/10.1002/pro.2424
    24 https://doi.org/10.1002/prot.24163
    25 https://doi.org/10.1002/prot.24185
    26 https://doi.org/10.1016/j.addr.2005.04.002
    27 https://doi.org/10.1016/j.bmcl.2007.07.072
    28 https://doi.org/10.1016/j.gene.2012.02.008
    29 https://doi.org/10.1016/j.ijantimicag.2012.04.014
    30 https://doi.org/10.1016/j.ijantimicag.2012.08.010
    31 https://doi.org/10.1016/j.ijantimicag.2012.10.010
    32 https://doi.org/10.1016/j.ijmm.2013.02.002
    33 https://doi.org/10.1016/j.jmb.2009.02.048
    34 https://doi.org/10.1016/j.meegid.2012.02.008
    35 https://doi.org/10.1016/j.tim.2011.09.005
    36 https://doi.org/10.1016/s1473-3099(10)70143-2
    37 https://doi.org/10.1016/s1473-3099(11)70059-7
    38 https://doi.org/10.1016/s1473-3099(11)70126-8
    39 https://doi.org/10.1016/s1473-3099(12)70317-1
    40 https://doi.org/10.1021/bi060320g
    41 https://doi.org/10.1039/c0cc05111j
    42 https://doi.org/10.1067/mic.2003.11
    43 https://doi.org/10.1073/pnas.0900693106
    44 https://doi.org/10.1073/pnas.1114944109
    45 https://doi.org/10.1073/pnas.1218348109
    46 https://doi.org/10.1073/pnas.1310333110
    47 https://doi.org/10.1073/pnas.1402358111
    48 https://doi.org/10.1074/jbc.m111.226936
    49 https://doi.org/10.1074/jbc.m111.246595
    50 https://doi.org/10.1086/324626
    51 https://doi.org/10.1089/mdr.2006.12.223
    52 https://doi.org/10.1089/mdr.2012.0250
    53 https://doi.org/10.1093/jac/dkn396
    54 https://doi.org/10.1093/jac/dkq431
    55 https://doi.org/10.1093/jac/dkq463
    56 https://doi.org/10.1093/jac/dkr431
    57 https://doi.org/10.1093/jac/dks084
    58 https://doi.org/10.1093/jac/dks357
    59 https://doi.org/10.1093/jac/dks373
    60 https://doi.org/10.1093/jac/dkt044
    61 https://doi.org/10.1093/jac/dkt078
    62 https://doi.org/10.1093/jac/dkt092
    63 https://doi.org/10.1093/jac/dkt341
    64 https://doi.org/10.1093/jac/dkt355
    65 https://doi.org/10.1093/jac/dkt540
    66 https://doi.org/10.1093/jac/dku140
    67 https://doi.org/10.1099/jmm.0.045799-0
    68 https://doi.org/10.1099/jmm.0.052555-0
    69 https://doi.org/10.1099/mic.0.045757-0
    70 https://doi.org/10.1111/j.1365-2958.2004.04449.x
    71 https://doi.org/10.1111/j.1365-2958.2008.06424.x
    72 https://doi.org/10.1111/j.1469-0691.2007.01857.x
    73 https://doi.org/10.1111/j.1469-0691.2007.01867.x
    74 https://doi.org/10.1111/j.1469-0691.2011.03715.x
    75 https://doi.org/10.1111/j.1574-6968.2004.tb09766.x
    76 https://doi.org/10.1111/j.1574-6976.2011.00268.x
    77 https://doi.org/10.1111/mmi.12211
    78 https://doi.org/10.1126/science.1220761
    79 https://doi.org/10.1128/aac.00079-11
    80 https://doi.org/10.1128/aac.00084-08
    81 https://doi.org/10.1128/aac.00131-06
    82 https://doi.org/10.1128/aac.00175-10
    83 https://doi.org/10.1128/aac.00187-11
    84 https://doi.org/10.1128/aac.00242-10
    85 https://doi.org/10.1128/aac.00284-09
    86 https://doi.org/10.1128/aac.00313-12
    87 https://doi.org/10.1128/aac.00580-10
    88 https://doi.org/10.1128/aac.00809-12
    89 https://doi.org/10.1128/aac.00848-12
    90 https://doi.org/10.1128/aac.00906-09
    91 https://doi.org/10.1128/aac.01004-09
    92 https://doi.org/10.1128/aac.01152-09
    93 https://doi.org/10.1128/aac.01473-13
    94 https://doi.org/10.1128/aac.01477-07
    95 https://doi.org/10.1128/aac.01480-13
    96 https://doi.org/10.1128/aac.01743-12
    97 https://doi.org/10.1128/aac.02005-12
    98 https://doi.org/10.1128/aac.02686-14
    99 https://doi.org/10.1128/aac.03110-14
    100 https://doi.org/10.1128/aac.05391-11
    101 https://doi.org/10.1128/aac.05441-11
    102 https://doi.org/10.1128/aac.05760-11
    103 https://doi.org/10.1128/aac.05870-11
    104 https://doi.org/10.1128/aac.06112-11
    105 https://doi.org/10.1128/aac.06142-11
    106 https://doi.org/10.1128/aac.32.11.1680
    107 https://doi.org/10.1128/aac.40.10.2380
    108 https://doi.org/10.1128/aac.41.10.2067
    109 https://doi.org/10.1128/aac.44.10.2861-2864.2000
    110 https://doi.org/10.1128/aac.44.6.1549-1555.2000
    111 https://doi.org/10.1128/aac.45.12.3595-3598.2001
    112 https://doi.org/10.1128/aac.45.4.1151-1161.2001
    113 https://doi.org/10.1128/aac.45.5.1550-1552.2001
    114 https://doi.org/10.1128/aac.46.9.3045-3049.2002
    115 https://doi.org/10.1128/aac.48.12.4793-4799.2004
    116 https://doi.org/10.1128/aac.48.5.1630-1639.2004
    117 https://doi.org/10.1128/aac.48.6.2292-2294.2004
    118 https://doi.org/10.1128/aac.49.1.161-169.2005
    119 https://doi.org/10.1128/aac.49.10.4390-4392.2005
    120 https://doi.org/10.1128/aem.07320-11
    121 https://doi.org/10.1128/cmr.00001-07
    122 https://doi.org/10.1128/cmr.00043-12
    123 https://doi.org/10.1128/cmr.05035-11
    124 https://doi.org/10.1128/cmr.19.2.382-402.2006
    125 https://doi.org/10.1128/jb.00565-13
    126 https://doi.org/10.1128/jb.01517-09
    127 https://doi.org/10.1128/jb.06582-11
    128 https://doi.org/10.1128/jb.183.13.3890-3902.2001
    129 https://doi.org/10.1128/jcm.00847-13
    130 https://doi.org/10.1128/jcm.01244-13
    131 https://doi.org/10.1128/jcm.01773-10
    132 https://doi.org/10.1128/mbio.00281-13
    133 https://doi.org/10.1128/mbio.00446-12
    134 https://doi.org/10.1146/annurev-micro-092412-155718
    135 https://doi.org/10.1146/annurev.biochem.78.082907.145923
    136 https://doi.org/10.1179/1973947813y.0000000075
    137 https://doi.org/10.1179/joc.2011.23.5.263
    138 https://doi.org/10.1371/journal.pone.0034953
    139 https://doi.org/10.1371/journal.pone.0051053
    140 https://doi.org/10.1371/journal.pone.0071151
    141 https://doi.org/10.1371/journal.pone.0082814
    142 https://doi.org/10.1371/journal.ppat.1000944
    143 https://doi.org/10.1517/14656566.2013.763030
    144 https://doi.org/10.1592/phco.30.12.1279
    145 https://doi.org/10.2174/15680266113136660220
    146 https://doi.org/10.2217/fmb.12.130
    147 https://doi.org/10.2741/1075
    148 https://doi.org/10.2807/1560-7917.es2013.18.31.20547
    149 https://doi.org/10.3109/1040841x.2012.691460
    150 https://doi.org/10.3201/eid1704.101009
    151 https://doi.org/10.3389/fmicb.2013.00138
    152 https://doi.org/10.3389/fmicb.2013.00212
    153 https://doi.org/10.3389/fmicb.2013.00213
    154 schema:datePublished 2015-01
    155 schema:datePublishedReg 2015-01-01
    156 schema:description Antibiotic-resistant bacteria that are difficult or impossible to treat are becoming increasingly common and are causing a global health crisis. Antibiotic resistance is encoded by several genes, many of which can transfer between bacteria. New resistance mechanisms are constantly being described, and new genes and vectors of transmission are identified on a regular basis. This article reviews recent advances in our understanding of the mechanisms by which bacteria are either intrinsically resistant or acquire resistance to antibiotics, including the prevention of access to drug targets, changes in the structure and protection of antibiotic targets and the direct modification or inactivation of antibiotics.
    157 schema:genre research_article
    158 schema:inLanguage en
    159 schema:isAccessibleForFree false
    160 schema:isPartOf N0ad027a0fcba471db5e87889d0892453
    161 N46530784e1944d93b54e301d13fbf60f
    162 sg:journal.1032854
    163 schema:name Molecular mechanisms of antibiotic resistance
    164 schema:pagination 42-51
    165 schema:productId N0aae76e3a10c4677bd87fb84c7ccbf6d
    166 N0d5b2d2f6c264adf95c648564c83f178
    167 N4dad54f51857478e8ff23de414973a43
    168 N5aa2ccec2c1d477d8e265dc844b2b55b
    169 Nc197dc5a236c4053a31a71bd8d7301e1
    170 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047623025
    171 https://doi.org/10.1038/nrmicro3380
    172 schema:sdDatePublished 2019-04-11T01:47
    173 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    174 schema:sdPublisher N3709a70978fe4a4787a196004ff50ef7
    175 schema:url http://www.nature.com/articles/nrmicro3380
    176 sgo:license sg:explorer/license/
    177 sgo:sdDataset articles
    178 rdf:type schema:ScholarlyArticle
    179 N0aae76e3a10c4677bd87fb84c7ccbf6d schema:name dimensions_id
    180 schema:value pub.1047623025
    181 rdf:type schema:PropertyValue
    182 N0ad027a0fcba471db5e87889d0892453 schema:issueNumber 1
    183 rdf:type schema:PublicationIssue
    184 N0d5b2d2f6c264adf95c648564c83f178 schema:name pubmed_id
    185 schema:value 25435309
    186 rdf:type schema:PropertyValue
    187 N2a43c2d0e66d4789b39f5f6731731d49 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    188 schema:name Anti-Bacterial Agents
    189 rdf:type schema:DefinedTerm
    190 N2c26cf58d22144e2869669ea63f073d6 rdf:first sg:person.01220046325.39
    191 rdf:rest N3cdce817977044659f2896f64d30a793
    192 N3709a70978fe4a4787a196004ff50ef7 schema:name Springer Nature - SN SciGraph project
    193 rdf:type schema:Organization
    194 N3cdce817977044659f2896f64d30a793 rdf:first sg:person.01040166173.37
    195 rdf:rest N5c71d376973c41f2aa97394d4e62a2f1
    196 N46530784e1944d93b54e301d13fbf60f schema:volumeNumber 13
    197 rdf:type schema:PublicationVolume
    198 N4dad54f51857478e8ff23de414973a43 schema:name readcube_id
    199 schema:value e2dd0db81b54817353ea5e68a53d0e6b6cb11d90df0ba2d17ca05f4369452e37
    200 rdf:type schema:PropertyValue
    201 N4eb5b84ca907497d8137c46a3febfb50 rdf:first sg:person.0670513324.70
    202 rdf:rest N2c26cf58d22144e2869669ea63f073d6
    203 N5aa2ccec2c1d477d8e265dc844b2b55b schema:name nlm_unique_id
    204 schema:value 101190261
    205 rdf:type schema:PropertyValue
    206 N5c71d376973c41f2aa97394d4e62a2f1 rdf:first sg:person.0665070460.43
    207 rdf:rest Nb46ea55c0a5a4ff089cebc74c0c7da20
    208 Na15832dbb99e4a7b82ba1d3502c9300a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    209 schema:name Signal Transduction
    210 rdf:type schema:DefinedTerm
    211 Nb46ea55c0a5a4ff089cebc74c0c7da20 rdf:first sg:person.0626621343.92
    212 rdf:rest rdf:nil
    213 Nc197dc5a236c4053a31a71bd8d7301e1 schema:name doi
    214 schema:value 10.1038/nrmicro3380
    215 rdf:type schema:PropertyValue
    216 Ncb057b83e97741d9bf0f39ee3812be93 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    217 schema:name Drug Resistance, Bacterial
    218 rdf:type schema:DefinedTerm
    219 Ne2ea35b77aa54752a81c7e84a852ee3c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    220 schema:name Bacteria
    221 rdf:type schema:DefinedTerm
    222 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    223 schema:name Medical and Health Sciences
    224 rdf:type schema:DefinedTerm
    225 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
    226 schema:name Medical Microbiology
    227 rdf:type schema:DefinedTerm
    228 sg:grant.2760163 http://pending.schema.org/fundedItem sg:pub.10.1038/nrmicro3380
    229 rdf:type schema:MonetaryGrant
    230 sg:journal.1032854 schema:issn 1740-1526
    231 1740-1534
    232 schema:name Nature Reviews Microbiology
    233 rdf:type schema:Periodical
    234 sg:person.01040166173.37 schema:affiliation https://www.grid.ac/institutes/grid.6572.6
    235 schema:familyName Baylay
    236 schema:givenName Alison J.
    237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01040166173.37
    238 rdf:type schema:Person
    239 sg:person.01220046325.39 schema:affiliation https://www.grid.ac/institutes/grid.6572.6
    240 schema:familyName Webber
    241 schema:givenName Mark A.
    242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220046325.39
    243 rdf:type schema:Person
    244 sg:person.0626621343.92 schema:affiliation https://www.grid.ac/institutes/grid.6572.6
    245 schema:familyName Piddock
    246 schema:givenName Laura J. V.
    247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626621343.92
    248 rdf:type schema:Person
    249 sg:person.0665070460.43 schema:affiliation https://www.grid.ac/institutes/grid.6572.6
    250 schema:familyName Ogbolu
    251 schema:givenName David O.
    252 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665070460.43
    253 rdf:type schema:Person
    254 sg:person.0670513324.70 schema:affiliation https://www.grid.ac/institutes/grid.6572.6
    255 schema:familyName Blair
    256 schema:givenName Jessica M. A.
    257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0670513324.70
    258 rdf:type schema:Person
    259 sg:pub.10.1007/s00284-012-0215-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023842442
    260 https://doi.org/10.1007/s00284-012-0215-3
    261 rdf:type schema:CreativeWork
    262 sg:pub.10.1007/s10096-012-1665-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1022890580
    263 https://doi.org/10.1007/s10096-012-1665-z
    264 rdf:type schema:CreativeWork
    265 sg:pub.10.1007/s10969-013-9154-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026172598
    266 https://doi.org/10.1007/s10969-013-9154-x
    267 rdf:type schema:CreativeWork
    268 sg:pub.10.1038/nature05076 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040864737
    269 https://doi.org/10.1038/nature05076
    270 rdf:type schema:CreativeWork
    271 sg:pub.10.1038/nature09743 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042954496
    272 https://doi.org/10.1038/nature09743
    273 rdf:type schema:CreativeWork
    274 sg:pub.10.1038/nature10388 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004674718
    275 https://doi.org/10.1038/nature10388
    276 rdf:type schema:CreativeWork
    277 sg:pub.10.1038/nature10641 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045294582
    278 https://doi.org/10.1038/nature10641
    279 rdf:type schema:CreativeWork
    280 sg:pub.10.1038/nature13205 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018733330
    281 https://doi.org/10.1038/nature13205
    282 rdf:type schema:CreativeWork
    283 sg:pub.10.1038/ncomms3078 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022876536
    284 https://doi.org/10.1038/ncomms3078
    285 rdf:type schema:CreativeWork
    286 sg:pub.10.1038/nrmicro2382 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022443334
    287 https://doi.org/10.1038/nrmicro2382
    288 rdf:type schema:CreativeWork
    289 sg:pub.10.1186/1471-2164-12-512 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038210304
    290 https://doi.org/10.1186/1471-2164-12-512
    291 rdf:type schema:CreativeWork
    292 sg:pub.10.1186/1757-4749-4-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001041264
    293 https://doi.org/10.1186/1757-4749-4-5
    294 rdf:type schema:CreativeWork
    295 https://app.dimensions.ai/details/publication/pub.1079528589 schema:CreativeWork
    296 https://doi.org/10.1001/jama.2013.280695 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036120723
    297 rdf:type schema:CreativeWork
    298 https://doi.org/10.1002/pro.2273 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012120238
    299 rdf:type schema:CreativeWork
    300 https://doi.org/10.1002/pro.2424 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023903314
    301 rdf:type schema:CreativeWork
    302 https://doi.org/10.1002/prot.24163 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045563939
    303 rdf:type schema:CreativeWork
    304 https://doi.org/10.1002/prot.24185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039215910
    305 rdf:type schema:CreativeWork
    306 https://doi.org/10.1016/j.addr.2005.04.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039058702
    307 rdf:type schema:CreativeWork
    308 https://doi.org/10.1016/j.bmcl.2007.07.072 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039289854
    309 rdf:type schema:CreativeWork
    310 https://doi.org/10.1016/j.gene.2012.02.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022832264
    311 rdf:type schema:CreativeWork
    312 https://doi.org/10.1016/j.ijantimicag.2012.04.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044369175
    313 rdf:type schema:CreativeWork
    314 https://doi.org/10.1016/j.ijantimicag.2012.08.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011738165
    315 rdf:type schema:CreativeWork
    316 https://doi.org/10.1016/j.ijantimicag.2012.10.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050160622
    317 rdf:type schema:CreativeWork
    318 https://doi.org/10.1016/j.ijmm.2013.02.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001131148
    319 rdf:type schema:CreativeWork
    320 https://doi.org/10.1016/j.jmb.2009.02.048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006412150
    321 rdf:type schema:CreativeWork
    322 https://doi.org/10.1016/j.meegid.2012.02.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031962958
    323 rdf:type schema:CreativeWork
    324 https://doi.org/10.1016/j.tim.2011.09.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018883000
    325 rdf:type schema:CreativeWork
    326 https://doi.org/10.1016/s1473-3099(10)70143-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047068088
    327 rdf:type schema:CreativeWork
    328 https://doi.org/10.1016/s1473-3099(11)70059-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002265687
    329 rdf:type schema:CreativeWork
    330 https://doi.org/10.1016/s1473-3099(11)70126-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008242137
    331 rdf:type schema:CreativeWork
    332 https://doi.org/10.1016/s1473-3099(12)70317-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005577038
    333 rdf:type schema:CreativeWork
    334 https://doi.org/10.1021/bi060320g schema:sameAs https://app.dimensions.ai/details/publication/pub.1055201819
    335 rdf:type schema:CreativeWork
    336 https://doi.org/10.1039/c0cc05111j schema:sameAs https://app.dimensions.ai/details/publication/pub.1011607095
    337 rdf:type schema:CreativeWork
    338 https://doi.org/10.1067/mic.2003.11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017983536
    339 rdf:type schema:CreativeWork
    340 https://doi.org/10.1073/pnas.0900693106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029780465
    341 rdf:type schema:CreativeWork
    342 https://doi.org/10.1073/pnas.1114944109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018953235
    343 rdf:type schema:CreativeWork
    344 https://doi.org/10.1073/pnas.1218348109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026749184
    345 rdf:type schema:CreativeWork
    346 https://doi.org/10.1073/pnas.1310333110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009909042
    347 rdf:type schema:CreativeWork
    348 https://doi.org/10.1073/pnas.1402358111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048554368
    349 rdf:type schema:CreativeWork
    350 https://doi.org/10.1074/jbc.m111.226936 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023532527
    351 rdf:type schema:CreativeWork
    352 https://doi.org/10.1074/jbc.m111.246595 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008829637
    353 rdf:type schema:CreativeWork
    354 https://doi.org/10.1086/324626 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004706151
    355 rdf:type schema:CreativeWork
    356 https://doi.org/10.1089/mdr.2006.12.223 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059297514
    357 rdf:type schema:CreativeWork
    358 https://doi.org/10.1089/mdr.2012.0250 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059297943
    359 rdf:type schema:CreativeWork
    360 https://doi.org/10.1093/jac/dkn396 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052167149
    361 rdf:type schema:CreativeWork
    362 https://doi.org/10.1093/jac/dkq431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043063047
    363 rdf:type schema:CreativeWork
    364 https://doi.org/10.1093/jac/dkq463 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023510883
    365 rdf:type schema:CreativeWork
    366 https://doi.org/10.1093/jac/dkr431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044944688
    367 rdf:type schema:CreativeWork
    368 https://doi.org/10.1093/jac/dks084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047590849
    369 rdf:type schema:CreativeWork
    370 https://doi.org/10.1093/jac/dks357 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049960340
    371 rdf:type schema:CreativeWork
    372 https://doi.org/10.1093/jac/dks373 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000986896
    373 rdf:type schema:CreativeWork
    374 https://doi.org/10.1093/jac/dkt044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029058116
    375 rdf:type schema:CreativeWork
    376 https://doi.org/10.1093/jac/dkt078 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047800478
    377 rdf:type schema:CreativeWork
    378 https://doi.org/10.1093/jac/dkt092 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053190655
    379 rdf:type schema:CreativeWork
    380 https://doi.org/10.1093/jac/dkt341 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031576615
    381 rdf:type schema:CreativeWork
    382 https://doi.org/10.1093/jac/dkt355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045723454
    383 rdf:type schema:CreativeWork
    384 https://doi.org/10.1093/jac/dkt540 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002287073
    385 rdf:type schema:CreativeWork
    386 https://doi.org/10.1093/jac/dku140 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040161296
    387 rdf:type schema:CreativeWork
    388 https://doi.org/10.1099/jmm.0.045799-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060391744
    389 rdf:type schema:CreativeWork
    390 https://doi.org/10.1099/jmm.0.052555-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027023216
    391 rdf:type schema:CreativeWork
    392 https://doi.org/10.1099/mic.0.045757-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043422263
    393 rdf:type schema:CreativeWork
    394 https://doi.org/10.1111/j.1365-2958.2004.04449.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020880594
    395 rdf:type schema:CreativeWork
    396 https://doi.org/10.1111/j.1365-2958.2008.06424.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1029023953
    397 rdf:type schema:CreativeWork
    398 https://doi.org/10.1111/j.1469-0691.2007.01857.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1028814910
    399 rdf:type schema:CreativeWork
    400 https://doi.org/10.1111/j.1469-0691.2007.01867.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048048999
    401 rdf:type schema:CreativeWork
    402 https://doi.org/10.1111/j.1469-0691.2011.03715.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1002839353
    403 rdf:type schema:CreativeWork
    404 https://doi.org/10.1111/j.1574-6968.2004.tb09766.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1030714777
    405 rdf:type schema:CreativeWork
    406 https://doi.org/10.1111/j.1574-6976.2011.00268.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1018812640
    407 rdf:type schema:CreativeWork
    408 https://doi.org/10.1111/mmi.12211 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035627979
    409 rdf:type schema:CreativeWork
    410 https://doi.org/10.1126/science.1220761 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015606282
    411 rdf:type schema:CreativeWork
    412 https://doi.org/10.1128/aac.00079-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036714486
    413 rdf:type schema:CreativeWork
    414 https://doi.org/10.1128/aac.00084-08 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039014870
    415 rdf:type schema:CreativeWork
    416 https://doi.org/10.1128/aac.00131-06 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021473563
    417 rdf:type schema:CreativeWork
    418 https://doi.org/10.1128/aac.00175-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022997111
    419 rdf:type schema:CreativeWork
    420 https://doi.org/10.1128/aac.00187-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046649668
    421 rdf:type schema:CreativeWork
    422 https://doi.org/10.1128/aac.00242-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033746892
    423 rdf:type schema:CreativeWork
    424 https://doi.org/10.1128/aac.00284-09 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011082453
    425 rdf:type schema:CreativeWork
    426 https://doi.org/10.1128/aac.00313-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041455740
    427 rdf:type schema:CreativeWork
    428 https://doi.org/10.1128/aac.00580-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031577358
    429 rdf:type schema:CreativeWork
    430 https://doi.org/10.1128/aac.00809-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017567560
    431 rdf:type schema:CreativeWork
    432 https://doi.org/10.1128/aac.00848-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041149291
    433 rdf:type schema:CreativeWork
    434 https://doi.org/10.1128/aac.00906-09 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030340035
    435 rdf:type schema:CreativeWork
    436 https://doi.org/10.1128/aac.01004-09 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041085747
    437 rdf:type schema:CreativeWork
    438 https://doi.org/10.1128/aac.01152-09 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027900306
    439 rdf:type schema:CreativeWork
    440 https://doi.org/10.1128/aac.01473-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023429384
    441 rdf:type schema:CreativeWork
    442 https://doi.org/10.1128/aac.01477-07 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003017407
    443 rdf:type schema:CreativeWork
    444 https://doi.org/10.1128/aac.01480-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024206929
    445 rdf:type schema:CreativeWork
    446 https://doi.org/10.1128/aac.01743-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010529944
    447 rdf:type schema:CreativeWork
    448 https://doi.org/10.1128/aac.02005-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009840115
    449 rdf:type schema:CreativeWork
    450 https://doi.org/10.1128/aac.02686-14 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040409189
    451 rdf:type schema:CreativeWork
    452 https://doi.org/10.1128/aac.03110-14 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017573025
    453 rdf:type schema:CreativeWork
    454 https://doi.org/10.1128/aac.05391-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042485925
    455 rdf:type schema:CreativeWork
    456 https://doi.org/10.1128/aac.05441-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031937922
    457 rdf:type schema:CreativeWork
    458 https://doi.org/10.1128/aac.05760-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024760487
    459 rdf:type schema:CreativeWork
    460 https://doi.org/10.1128/aac.05870-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027594543
    461 rdf:type schema:CreativeWork
    462 https://doi.org/10.1128/aac.06112-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042444311
    463 rdf:type schema:CreativeWork
    464 https://doi.org/10.1128/aac.06142-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031265626
    465 rdf:type schema:CreativeWork
    466 https://doi.org/10.1128/aac.32.11.1680 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050717946
    467 rdf:type schema:CreativeWork
    468 https://doi.org/10.1128/aac.40.10.2380 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082989036
    469 rdf:type schema:CreativeWork
    470 https://doi.org/10.1128/aac.41.10.2067 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083159784
    471 rdf:type schema:CreativeWork
    472 https://doi.org/10.1128/aac.44.10.2861-2864.2000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002851532
    473 rdf:type schema:CreativeWork
    474 https://doi.org/10.1128/aac.44.6.1549-1555.2000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008670270
    475 rdf:type schema:CreativeWork
    476 https://doi.org/10.1128/aac.45.12.3595-3598.2001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037807721
    477 rdf:type schema:CreativeWork
    478 https://doi.org/10.1128/aac.45.4.1151-1161.2001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044793518
    479 rdf:type schema:CreativeWork
    480 https://doi.org/10.1128/aac.45.5.1550-1552.2001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034108055
    481 rdf:type schema:CreativeWork
    482 https://doi.org/10.1128/aac.46.9.3045-3049.2002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033656859
    483 rdf:type schema:CreativeWork
    484 https://doi.org/10.1128/aac.48.12.4793-4799.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050882193
    485 rdf:type schema:CreativeWork
    486 https://doi.org/10.1128/aac.48.5.1630-1639.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030557673
    487 rdf:type schema:CreativeWork
    488 https://doi.org/10.1128/aac.48.6.2292-2294.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018911010
    489 rdf:type schema:CreativeWork
    490 https://doi.org/10.1128/aac.49.1.161-169.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035149545
    491 rdf:type schema:CreativeWork
    492 https://doi.org/10.1128/aac.49.10.4390-4392.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022393691
    493 rdf:type schema:CreativeWork
    494 https://doi.org/10.1128/aem.07320-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047509330
    495 rdf:type schema:CreativeWork
    496 https://doi.org/10.1128/cmr.00001-07 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008817892
    497 rdf:type schema:CreativeWork
    498 https://doi.org/10.1128/cmr.00043-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016255794
    499 rdf:type schema:CreativeWork
    500 https://doi.org/10.1128/cmr.05035-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040580528
    501 rdf:type schema:CreativeWork
    502 https://doi.org/10.1128/cmr.19.2.382-402.2006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025712748
    503 rdf:type schema:CreativeWork
    504 https://doi.org/10.1128/jb.00565-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014496387
    505 rdf:type schema:CreativeWork
    506 https://doi.org/10.1128/jb.01517-09 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000865038
    507 rdf:type schema:CreativeWork
    508 https://doi.org/10.1128/jb.06582-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009293241
    509 rdf:type schema:CreativeWork
    510 https://doi.org/10.1128/jb.183.13.3890-3902.2001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011170777
    511 rdf:type schema:CreativeWork
    512 https://doi.org/10.1128/jcm.00847-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021539863
    513 rdf:type schema:CreativeWork
    514 https://doi.org/10.1128/jcm.01244-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022196805
    515 rdf:type schema:CreativeWork
    516 https://doi.org/10.1128/jcm.01773-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015385487
    517 rdf:type schema:CreativeWork
    518 https://doi.org/10.1128/mbio.00281-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043557265
    519 rdf:type schema:CreativeWork
    520 https://doi.org/10.1128/mbio.00446-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032807575
    521 rdf:type schema:CreativeWork
    522 https://doi.org/10.1146/annurev-micro-092412-155718 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011255487
    523 rdf:type schema:CreativeWork
    524 https://doi.org/10.1146/annurev.biochem.78.082907.145923 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049536673
    525 rdf:type schema:CreativeWork
    526 https://doi.org/10.1179/1973947813y.0000000075 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020231250
    527 rdf:type schema:CreativeWork
    528 https://doi.org/10.1179/joc.2011.23.5.263 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005876828
    529 rdf:type schema:CreativeWork
    530 https://doi.org/10.1371/journal.pone.0034953 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042503168
    531 rdf:type schema:CreativeWork
    532 https://doi.org/10.1371/journal.pone.0051053 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020495072
    533 rdf:type schema:CreativeWork
    534 https://doi.org/10.1371/journal.pone.0071151 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037163085
    535 rdf:type schema:CreativeWork
    536 https://doi.org/10.1371/journal.pone.0082814 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042587583
    537 rdf:type schema:CreativeWork
    538 https://doi.org/10.1371/journal.ppat.1000944 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043789254
    539 rdf:type schema:CreativeWork
    540 https://doi.org/10.1517/14656566.2013.763030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032333627
    541 rdf:type schema:CreativeWork
    542 https://doi.org/10.1592/phco.30.12.1279 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033967985
    543 rdf:type schema:CreativeWork
    544 https://doi.org/10.2174/15680266113136660220 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069194717
    545 rdf:type schema:CreativeWork
    546 https://doi.org/10.2217/fmb.12.130 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013438110
    547 rdf:type schema:CreativeWork
    548 https://doi.org/10.2741/1075 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070913383
    549 rdf:type schema:CreativeWork
    550 https://doi.org/10.2807/1560-7917.es2013.18.31.20547 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070926095
    551 rdf:type schema:CreativeWork
    552 https://doi.org/10.3109/1040841x.2012.691460 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024653201
    553 rdf:type schema:CreativeWork
    554 https://doi.org/10.3201/eid1704.101009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022816510
    555 rdf:type schema:CreativeWork
    556 https://doi.org/10.3389/fmicb.2013.00138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019231953
    557 rdf:type schema:CreativeWork
    558 https://doi.org/10.3389/fmicb.2013.00212 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038173588
    559 rdf:type schema:CreativeWork
    560 https://doi.org/10.3389/fmicb.2013.00213 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048052896
    561 rdf:type schema:CreativeWork
    562 https://www.grid.ac/institutes/grid.6572.6 schema:alternateName University of Birmingham
    563 schema:name Antimicrobials Research Group, School of Immunity and Infection, Institute for Microbiology and Infection, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
    564 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...