Molecular mechanisms of Escherichia coli pathogenicity View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-01

AUTHORS

Matthew A Croxen, B Brett Finlay

ABSTRACT

Escherichia coli is a remarkable and diverse organism. This normally harmless commensal needs only to acquire a combination of mobile genetic elements to become a highly adapted pathogen capable of causing a range of diseases, from gastroenteritis to extraintestinal infections of the urinary tract, bloodstream and central nervous system. The worldwide burden of these diseases is staggering, with hundreds of millions of people affected annually. Eight E. coli pathovars have been well characterized, and each uses a large arsenal of virulence factors to subvert host cellular functions to potentiate its virulence. In this Review, we focus on the recent advances in our understanding of the different pathogenic mechanisms that are used by various E. coli pathovars and how they cause disease in humans. More... »

PAGES

26-38

References to SciGraph publications

  • 2008-01. The versatility of Shigella effectors in NATURE REVIEWS MICROBIOLOGY
  • 2009-08. Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2007-01. Shigella IpgB1 promotes bacterial entry through the ELMO–Dock180 machinery in NATURE CELL BIOLOGY
  • 2008-02. Inter-kingdom signalling: communication between bacteria and their hosts in NATURE REVIEWS MICROBIOLOGY
  • 2008-08. The pathogen protein EspFU hijacks actin polymerization using mimicry and multivalency in NATURE
  • 2001-09. Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells in NATURE CELL BIOLOGY
  • 2009-05. Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment in NATURE
  • 2008-08. Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspFU in NATURE
  • 1999-10. Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals in NATURE CELL BIOLOGY
  • 2008-08. Mechanisms of microbial traversal of the blood–brain barrier in NATURE REVIEWS MICROBIOLOGY
  • 2004-02. Pathogenic Escherichia coli in NATURE REVIEWS MICROBIOLOGY
  • 2009-01. Enterotoxigenic Escherichia coli EtpA mediates adhesion between flagella and host cells in NATURE
  • 2007-10-18. Manipulation of host-cell pathways by bacterial pathogens in NATURE
  • 2007-01. An injected bacterial effector targets chromatin access for transcription factor NF-κB to alter transcription of host genes involved in immune responses in NATURE IMMUNOLOGY
  • 2004-07. Phosphorylation of the enteropathogenic E. coli receptor by the Src-family kinase c-Fyn triggers actin pedestal formation in NATURE CELL BIOLOGY
  • 2007-11. Shiga toxin induces tubular membrane invaginations for its uptake into cells in NATURE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrmicro2265

    DOI

    http://dx.doi.org/10.1038/nrmicro2265

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1039970366

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19966814


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