Epidemiological interpretation of antibiotic resistance studies – what are we missing? View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-12

AUTHORS

Mitchell J. Schwaber, Tali De-Medina, Yehuda Carmeli

ABSTRACT

Antimicrobial resistance is an emerging public-health threat. Studies of the relationship between antibiotic use and resistance, as well as surveillance programmes, examine changes in the proportion of isolates that are resistant. Although proportions are helpful to the clinician prescribing empirical therapy, proportion-based analyses can be misleading to the public-health professional as they can yield biased estimates. Proportions do not adequately reflect the burden of resistance, a measure often of interest in public health. A more appropriate measure of this burden is the rate of isolation of resistant organisms, that is, the absolute number of resistant isolates in a population over time. More... »

PAGES

979-983

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nrmicro1047

DOI

http://dx.doi.org/10.1038/nrmicro1047

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1020160327

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15550943


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