Protein engineering 20 years on View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-12

AUTHORS

James A. Brannigan, Anthony J. Wilkinson

ABSTRACT

It is 20 years since site-directed mutagenesis was first used to modify the active site of an enzyme of known structure and mechanism. Since then, this method has contributed far-reaching insights into catalysis, specificity, stability and folding of proteins. Engineered proteins are now being used in industry and for the improved treatment of human disease. More... »

PAGES

964-970

References to SciGraph publications

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  • Journal

    TITLE

    Nature Reviews Molecular Cell Biology

    ISSUE

    12

    VOLUME

    3

    Author Affiliations

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrm975

    DOI

    http://dx.doi.org/10.1038/nrm975

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1045034030

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/12461562


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