Apoptosis: IAP proteins: blocking the road to death's door View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-06

AUTHORS

Guy S. Salvesen, Colin S. Duckett

ABSTRACT

The 'inhibitor of apoptosis' (IAP) gene family, which was discovered less than a decade ago, encodes a group of structurally related proteins that, in addition to their ability to suppress apoptotic cell death, are involved in an increasing number of seemingly unrelated cellular functions. Here, we review the functional and structural properties of this fascinating group of proteins, and of several recently identified IAP-binding factors that regulate IAP function. More... »

PAGES

401-410

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    URI

    http://scigraph.springernature.com/pub.10.1038/nrm830

    DOI

    http://dx.doi.org/10.1038/nrm830

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1016013058

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/12042762


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