TGFβ signalling in context View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-10

AUTHORS

Joan Massagué

ABSTRACT

The basic elements of the transforming growth factor-β (TGFβ) pathway were revealed more than a decade ago. Since then, the concept of how the TGFβ signal travels from the membrane to the nucleus has been enriched with additional findings, and its multifunctional nature and medical relevance have relentlessly come to light. However, an old mystery has endured: how does the context determine the cellular response to TGFβ? Solving this question is key to understanding TGFβ biology and its many malfunctions. Recent progress is pointing at answers. More... »

PAGES

616

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrm3434

    DOI

    http://dx.doi.org/10.1038/nrm3434

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1052520145

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22992590


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