MET signalling: principles and functions in development, organ regeneration and cancer View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-12

AUTHORS

Livio Trusolino, Andrea Bertotti, Paolo M. Comoglio

ABSTRACT

The MET tyrosine kinase receptor (also known as the HGF receptor) promotes tissue remodelling, which underlies developmental morphogenesis, wound repair, organ homeostasis and cancer metastasis, by integrating growth, survival and migration cues in response to environmental stimuli or cell-autonomous perturbations. The versatility of MET-mediated biological responses is sustained by qualitative and quantitative signal modulation. Qualitative mechanisms include the engagement of dedicated signal transducers and the subcellular compartmentalization of MET signalling pathways, whereas quantitative regulation involves MET partnering with adaptor amplifiers or being degraded through the shedding of its extracellular domain or through intracellular ubiquitylation. Controlled activation of MET signalling can be exploited in regenerative medicine, whereas MET inhibition might slow down tumour progression. More... »

PAGES

834

References to SciGraph publications

  • 2007-05. Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses in NATURE REVIEWS DRUG DISCOVERY
  • 2005-01. HGF/SF-Met signaling in tumor progression in CELL RESEARCH
  • 2001-05. Down-regulation of MET, the receptor for hepatocyte growth factor in ONCOGENE
  • 1989-05. Tyrosine kinase receptor indistinguishable from the c-met protein in NATURE
  • 2008-11. From cells to organs: building polarized tissue in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 1997-05. Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas in NATURE GENETICS
  • 1995-02. Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor in NATURE
  • 2004-02. Network biology: understanding the cell's functional organization in NATURE REVIEWS GENETICS
  • 2002-04. Scatter-factor and semaphorin receptors: cell signalling for invasive growth in NATURE REVIEWS CANCER
  • 1998-01. Induction of epithelial tubules by growth factor HGF depends on the STAT pathway in NATURE
  • 2002-01. Requirement of Stat3 signaling for HGF/SF-Met mediated tumorigenesis in ONCOGENE
  • 2003-12. Met, metastasis, motility and more in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2000-11. Met receptor tyrosine kinase: enhanced signaling through adapter proteins in ONCOGENE
  • 1995-08. Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud in NATURE
  • 2007-04. Amplification of apoptosis through sequential caspase cleavage of the MET tyrosine kinase receptor in CELL DEATH & DIFFERENTIATION
  • 1987-05. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility in NATURE
  • 2004-07. Interplay between scatter factor receptors and B plexins controls invasive growth in ONCOGENE
  • 2000-12. A switch from p130Cas/Crk to Gab1/Crk signaling correlates with anchorage independent growth and JNK activation in cells transformed by the Met receptor oncoprotein in ONCOGENE
  • 2009-03. Epidermal homeostasis: a balancing act of stem cells in the skin in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2010-01. The endocytic matrix in NATURE
  • 2002-04. NF-κB in cancer: from innocent bystander to major culprit in NATURE REVIEWS CANCER
  • 1996-11. Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis in NATURE
  • 2005-09. Modelling glandular epithelial cancers in three-dimensional cultures in NATURE REVIEWS CANCER
  • 2010-02. PKC and the control of localized signal dynamics in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 1999-12. Met-induced JNK activation is mediated by the adapter protein Crk and correlates with the Gab1 – Crk signaling complex formation in ONCOGENE
  • 2007-02. From Tpr-Met to Met, tumorigenesis and tubes in ONCOGENE
  • 2000-03. Sustained recruitment of phospholipase C-γ to Gab1 is required for HGF-induced branching tubulogenesis in ONCOGENE
  • 2008-08. Cancer as an overhealing wound: an old hypothesis revisited in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2005-03. Role of NF-κB signaling in hepatocyte growth factor/scatter factor-mediated cell protection in ONCOGENE
  • 1999-02. Concomitant activation of pathways downstream of Grb2 and PI 3-kinase is required for MET-mediated metastasis in ONCOGENE
  • 2004-11. Stromal fibroblasts in cancer initiation and progression in NATURE
  • 2007-04. A module of negative feedback regulators defines growth factor signaling in NATURE GENETICS
  • 2003-01. CD44: From adhesion molecules to signalling regulators in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2002-09. The Semaphorin 4D receptor controls invasive growth by coupling with Met in NATURE CELL BIOLOGY
  • 1999-02. Hepatocyte growth factor gene therapy of liver cirrhosis in rats in NATURE MEDICINE
  • 2002-03. The endophilin–CIN85–Cbl complex mediates ligand-dependent downregulation of c-Met in NATURE
  • 2006-05. New signals from the invasive front in NATURE
  • 2002-02. Hepatocyte growth factor/scatter factor activates proliferation in melanoma cells through p38 MAPK, ATF-2 and cyclin D1 in ONCOGENE
  • 2009-09. Endocytosis and signalling: intertwining molecular networks in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 1995-02. Scatter factor/hepatocyte growth factor is essential for liver development in NATURE
  • 2008-06. Drug development of MET inhibitors: targeting oncogene addiction and expedience in NATURE REVIEWS DRUG DISCOVERY
  • 2002-03. Signal transduction: Molecular ticket to enter cells in NATURE
  • 2008-05-15. Wound repair and regeneration in NATURE
  • 2007-08. Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion in BRITISH JOURNAL OF CANCER
  • 1989-11. Molecular cloning and expression of human hepatocyte growth factor in NATURE
  • 2004-07. Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis in ONCOGENE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrm3012

    DOI

    http://dx.doi.org/10.1038/nrm3012

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1002993405

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/21102609


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biochemistry and Cell Biology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animal Structures", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Growth and Development", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Models, Biological", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Models, Molecular", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Proto-Oncogene Proteins c-met", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Regeneration", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Signal Transduction", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Candiolo Cancer Institute", 
              "id": "https://www.grid.ac/institutes/grid.419555.9", 
              "name": [
                "Institute for Cancer Research and Treatment (IRCC), University of Torino Medical School, 10060 Candiolo, Torino, Italy."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Trusolino", 
            "givenName": "Livio", 
            "id": "sg:person.0772247030.82", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772247030.82"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Candiolo Cancer Institute", 
              "id": "https://www.grid.ac/institutes/grid.419555.9", 
              "name": [
                "Institute for Cancer Research and Treatment (IRCC), University of Torino Medical School, 10060 Candiolo, Torino, Italy."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bertotti", 
            "givenName": "Andrea", 
            "id": "sg:person.01274134276.83", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274134276.83"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Candiolo Cancer Institute", 
              "id": "https://www.grid.ac/institutes/grid.419555.9", 
              "name": [
                "Institute for Cancer Research and Treatment (IRCC), University of Torino Medical School, 10060 Candiolo, Torino, Italy."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Comoglio", 
            "givenName": "Paolo M.", 
            "id": "sg:person.01070076557.01", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070076557.01"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/j.cell.2006.02.025", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000172640"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1038/sj.emboj.7600396", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001191060"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0006-291x(05)81187-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001445662"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1097-4652(2000)9999:9999<000::aid-jcp1033>3.0.co;2-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002040972"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1083/jcb.200901129", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002220904"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/327239a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002266258", 
              "https://doi.org/10.1038/327239a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1242/jcs.030197", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003112306"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature04872", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003500438", 
              "https://doi.org/10.1038/nature04872"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature04872", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003500438", 
              "https://doi.org/10.1038/nature04872"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature04872", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003500438", 
              "https://doi.org/10.1038/nature04872"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc1695", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003902023", 
              "https://doi.org/10.1038/nrc1695"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc1695", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003902023", 
              "https://doi.org/10.1038/nrc1695"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ncb843", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004186791", 
              "https://doi.org/10.1038/ncb843"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ncb843", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004186791", 
              "https://doi.org/10.1038/ncb843"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/carcin/bgh227", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004227312"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.02253-05", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004880527"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1072682", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005671466"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(05)78259-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005963147"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0896-6273(00)80466-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006228430"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m805916200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006610999"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrd2530", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006672418", 
              "https://doi.org/10.1038/nrd2530"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.273.50.33714", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006950258"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1083/jcb.150.6.1375", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007749916"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc779", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007964460", 
              "https://doi.org/10.1038/nrc779"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc779", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007964460", 
              "https://doi.org/10.1038/nrc779"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bj20091448", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008162532"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bj20091448", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008162532"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.devcel.2008.05.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008314667"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/emboj/16.10.2634", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009144692"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(94)90318-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009238656"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/342440a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009687593", 
              "https://doi.org/10.1038/342440a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.88.16.7001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010182145"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0702555104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010323142"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0955-0674(03)00096-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010382040"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0955-0674(03)00096-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010382040"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/path.2277", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010508721"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm2455", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012647427", 
              "https://doi.org/10.1038/nrm2455"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ijc.21766", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012791881"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ijc.21766", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012791881"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccr.2004.07.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012945779"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/376768a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013243841", 
              "https://doi.org/10.1038/376768a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m800186200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013469916"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.tibs.2003.09.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013808314"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.tibs.2003.09.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013808314"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.94.25.13868", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014411971"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.271.22.13116", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014432779"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.cr.7290264", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014667344", 
              "https://doi.org/10.1038/sj.cr.7290264"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.cr.7290264", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014667344", 
              "https://doi.org/10.1038/sj.cr.7290264"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.10358", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015355049"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm2748", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015441819", 
              "https://doi.org/10.1038/nrm2748"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm2748", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015441819", 
              "https://doi.org/10.1038/nrm2748"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m512298200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015781559"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/humu.21374", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016333807"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/humu.21374", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016333807"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0962-8924(03)00104-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016623110"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0962-8924(03)00104-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016623110"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1083/jcb.200605114", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016986122"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2009.11.007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017006433"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/416133a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017601282", 
              "https://doi.org/10.1038/416133a"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/416133a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017601282", 
              "https://doi.org/10.1038/416133a"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1203859", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017661502", 
              "https://doi.org/10.1038/sj.onc.1203859"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1203859", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017661502", 
              "https://doi.org/10.1038/sj.onc.1203859"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m410012200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018088912"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccr.2004.05.032", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018217404"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg1272", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018231980", 
              "https://doi.org/10.1038/nrg1272"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg1272", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018231980", 
              "https://doi.org/10.1038/nrg1272"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1600-0854.2005.00290.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018353378"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1600-0854.2005.00290.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018353378"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/339155a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018635692", 
              "https://doi.org/10.1038/339155a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/416187a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019096765", 
              "https://doi.org/10.1038/416187a"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/416187a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019096765", 
              "https://doi.org/10.1038/416187a"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0896-6273(03)00493-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019221689"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.devcel.2004.06.015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019410848"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ijc.1595", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019793540"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.270.46.27780", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020892755"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1083/jcb.123.1.223", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021041037"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.cdd.4402080", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021721025", 
              "https://doi.org/10.1038/sj.cdd.4402080"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.cdd.4402080", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021721025", 
              "https://doi.org/10.1038/sj.cdd.4402080"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.273.30.18793", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022148973"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m003597200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023018536"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm2636", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023434470", 
              "https://doi.org/10.1038/nrm2636"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1205004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023491583", 
              "https://doi.org/10.1038/sj.onc.1205004"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1205004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023491583", 
              "https://doi.org/10.1038/sj.onc.1205004"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc780", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024581782", 
              "https://doi.org/10.1038/nrc780"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc780", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024581782", 
              "https://doi.org/10.1038/nrc780"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m302116200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024926716"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2004-07-2885", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025396562"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m407769200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025485527"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1091/mbc.e06-09-0823", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025595648"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.11.12.5954", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025596508"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci39104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026879393"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci39104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026879393"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/1078-0432.ccr-10-0106", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026911925"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1083/jcb.200701086", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026928336"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0306068101", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026992033"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1202607", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027189119", 
              "https://doi.org/10.1038/sj.onc.1202607"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1202607", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027189119", 
              "https://doi.org/10.1038/sj.onc.1202607"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m107551200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027334376"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1083/jcb.149.7.1419", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027555981"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0006-291x(89)92316-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028656274"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccr.2009.10.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029310321"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.275.15.10772", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029368156"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0955-0674(00)00251-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030166395"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(86)90564-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030560653"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature07039", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030873761", 
              "https://doi.org/10.1038/nature07039"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1207646", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030876928", 
              "https://doi.org/10.1038/sj.onc.1207646"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1207646", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030876928", 
              "https://doi.org/10.1038/sj.onc.1207646"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-9440(10)62323-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030900957"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1097-2765(01)00378-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031065445"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1091/mbc.e06-08-0674", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031691994"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0898-6568(99)00060-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031991548"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/384173a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032028837", 
              "https://doi.org/10.1038/384173a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng1987", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032102166", 
              "https://doi.org/10.1038/ng1987"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm2523", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032396036", 
              "https://doi.org/10.1038/nrm2523"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-03-2383", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032451222"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/5593", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032649050", 
              "https://doi.org/10.1038/5593"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/5593", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032649050", 
              "https://doi.org/10.1038/5593"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m702573200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033163137"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.11.24.3341", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033218196"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0962-8924(98)01359-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033287811"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1207650", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033545030", 
              "https://doi.org/10.1038/sj.onc.1207650"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1207650", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033545030", 
              "https://doi.org/10.1038/sj.onc.1207650"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.98.1.247", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034658483"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.24.23.10328-10339.2004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034912857"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1161431", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035033278"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng0597-68", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035254306", 
              "https://doi.org/10.1038/ng0597-68"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.devcel.2004.06.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035846094"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm1261", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036162157", 
              "https://doi.org/10.1038/nrm1261"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm1261", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036162157", 
              "https://doi.org/10.1038/nrm1261"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0707498104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036732228"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.22.4.1060-1072.2002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036812375"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m110.106435", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037022518"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.25.10.3982-3996.2005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037103664"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm2847", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037228915", 
              "https://doi.org/10.1038/nrm2847"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm2847", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037228915", 
              "https://doi.org/10.1038/nrm2847"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1097-2765(01)00261-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039529656"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1161/hh0102.102756", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039844636"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-05-2827", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040314736"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/373699a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040388169", 
              "https://doi.org/10.1038/373699a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1204475", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040457827", 
              "https://doi.org/10.1038/sj.onc.1204475"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1204475", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040457827", 
              "https://doi.org/10.1038/sj.onc.1204475"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrd2289", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040589518", 
              "https://doi.org/10.1038/nrd2289"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1096/fj.04-1535fje", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040662362"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1091/mbc.e08-09-0969", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041112390"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.tcb.2009.07.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041805638"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.bjc.6603884", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041940900", 
              "https://doi.org/10.1038/sj.bjc.6603884"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m210656200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042583933"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1091/mbc.9.8.2185", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043136045"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci38075", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043159224"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci38075", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043159224"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(91)90363-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043779064"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0092-8674(01)00567-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043857082"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1083/jcb.200806076", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043877787"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm1004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044326367", 
              "https://doi.org/10.1038/nrm1004"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm1004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044326367", 
              "https://doi.org/10.1038/nrm1004"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1535-6108(03)00085-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044383357"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0006-2952(95)00219-p", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045433594"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/373702a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045696614", 
              "https://doi.org/10.1038/373702a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1203198", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046015028", 
              "https://doi.org/10.1038/sj.onc.1203198"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1203198", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046015028", 
              "https://doi.org/10.1038/sj.onc.1203198"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-08-1688", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046143763"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0403412101", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046591274"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-08-2148", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048161861"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.242602", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048510702"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1210201", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048606887", 
              "https://doi.org/10.1038/sj.onc.1210201"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0707270105", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048800685"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1205150", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048836587", 
              "https://doi.org/10.1038/sj.onc.1205150"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1205150", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048836587", 
              "https://doi.org/10.1038/sj.onc.1205150"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m800727200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049581993"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature08910", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049800104", 
              "https://doi.org/10.1038/nature08910"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature08910", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049800104", 
              "https://doi.org/10.1038/nature08910"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-9440(10)63689-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049830806"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1203977", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049903632", 
              "https://doi.org/10.1038/sj.onc.1203977"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1203977", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049903632", 
              "https://doi.org/10.1038/sj.onc.1203977"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.20.22.8513-8525.2000", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050294945"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0508776103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050433384"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1152/ajprenal.00451.2003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050500132"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-10-0145", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050520970"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1203514", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051008900", 
              "https://doi.org/10.1038/sj.onc.1203514"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1203514", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051008900", 
              "https://doi.org/10.1038/sj.onc.1203514"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1208327", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051138612", 
              "https://doi.org/10.1038/sj.onc.1208327"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1208327", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051138612", 
              "https://doi.org/10.1038/sj.onc.1208327"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03096", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051657854", 
              "https://doi.org/10.1038/nature03096"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03096", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051657854", 
              "https://doi.org/10.1038/nature03096"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m110.134031", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052151458"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.19.3.1784", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052260320"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1038/sj.emboj.7600243", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052262305"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/34657", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052561190", 
              "https://doi.org/10.1038/34657"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/34657", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052561190", 
              "https://doi.org/10.1038/34657"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0508156103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053298396"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1097-2765(02)00439-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053474783"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.asn.0000130568.53923.fd", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060319638"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.asn.0000130568.53923.fd", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060319638"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.asn.0000130568.53923.fd", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060319638"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1162783", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062458588"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1846706", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062509911"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.276.5309.60", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062556261"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/scisignal.2000643", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062682180"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4161/cc.4.3.1519", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1072298227"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074673343", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074776556", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/j.1460-2075.1991.tb07836.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077206922"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077608194", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078975891", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082483991", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082671742", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082678010", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082775305", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1083350373", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2010-12", 
        "datePublishedReg": "2010-12-01", 
        "description": "The MET tyrosine kinase receptor (also known as the HGF receptor) promotes tissue remodelling, which underlies developmental morphogenesis, wound repair, organ homeostasis and cancer metastasis, by integrating growth, survival and migration cues in response to environmental stimuli or cell-autonomous perturbations. The versatility of MET-mediated biological responses is sustained by qualitative and quantitative signal modulation. Qualitative mechanisms include the engagement of dedicated signal transducers and the subcellular compartmentalization of MET signalling pathways, whereas quantitative regulation involves MET partnering with adaptor amplifiers or being degraded through the shedding of its extracellular domain or through intracellular ubiquitylation. Controlled activation of MET signalling can be exploited in regenerative medicine, whereas MET inhibition might slow down tumour progression.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1038/nrm3012", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1023609", 
            "issn": [
              "1471-0072", 
              "1471-0080"
            ], 
            "name": "Nature Reviews Molecular Cell Biology", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "12", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "11"
          }
        ], 
        "name": "MET signalling: principles and functions in development, organ regeneration and cancer", 
        "pagination": "834", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "0e41818b4179ba8d1492b4587429eeff1ee774fc3e7a4d3c7288668dd49692d8"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "21102609"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "100962782"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/nrm3012"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1002993405"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/nrm3012", 
          "https://app.dimensions.ai/details/publication/pub.1002993405"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T11:00", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000352_0000000352/records_60339_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://www.nature.com/articles/nrm3012"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nrm3012'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nrm3012'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nrm3012'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nrm3012'


     

    This table displays all metadata directly associated to this object as RDF triples.

    664 TRIPLES      21 PREDICATES      207 URIs      31 LITERALS      19 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/nrm3012 schema:about N1150787ffcb846d387e9ca58d911e133
    2 N3664ab74e18b43ecbb555161f7b34062
    3 N44cddc01dcd34eb8bce6be32b9cf2a0f
    4 N4ae85f6d787f47fbb2ce6a5b4b0e8bae
    5 N6371faa688ea447d828f8963cb13a9a6
    6 N7e1279352646466ea369d06221798efa
    7 Na58a3291aba7463a9cbdf07377c8652a
    8 Nd522dca38ef64085a93084d10628aacc
    9 Ndbb7c91169e049b5aa14de7885acf98c
    10 Nf781647fb5fe45aab224d424b302c40d
    11 anzsrc-for:06
    12 anzsrc-for:0601
    13 schema:author N5529c87593cf42f2ab2932e39094d50a
    14 schema:citation sg:pub.10.1038/327239a0
    15 sg:pub.10.1038/339155a0
    16 sg:pub.10.1038/342440a0
    17 sg:pub.10.1038/34657
    18 sg:pub.10.1038/373699a0
    19 sg:pub.10.1038/373702a0
    20 sg:pub.10.1038/376768a0
    21 sg:pub.10.1038/384173a0
    22 sg:pub.10.1038/416133a
    23 sg:pub.10.1038/416187a
    24 sg:pub.10.1038/5593
    25 sg:pub.10.1038/nature03096
    26 sg:pub.10.1038/nature04872
    27 sg:pub.10.1038/nature07039
    28 sg:pub.10.1038/nature08910
    29 sg:pub.10.1038/ncb843
    30 sg:pub.10.1038/ng0597-68
    31 sg:pub.10.1038/ng1987
    32 sg:pub.10.1038/nrc1695
    33 sg:pub.10.1038/nrc779
    34 sg:pub.10.1038/nrc780
    35 sg:pub.10.1038/nrd2289
    36 sg:pub.10.1038/nrd2530
    37 sg:pub.10.1038/nrg1272
    38 sg:pub.10.1038/nrm1004
    39 sg:pub.10.1038/nrm1261
    40 sg:pub.10.1038/nrm2455
    41 sg:pub.10.1038/nrm2523
    42 sg:pub.10.1038/nrm2636
    43 sg:pub.10.1038/nrm2748
    44 sg:pub.10.1038/nrm2847
    45 sg:pub.10.1038/sj.bjc.6603884
    46 sg:pub.10.1038/sj.cdd.4402080
    47 sg:pub.10.1038/sj.cr.7290264
    48 sg:pub.10.1038/sj.onc.1202607
    49 sg:pub.10.1038/sj.onc.1203198
    50 sg:pub.10.1038/sj.onc.1203514
    51 sg:pub.10.1038/sj.onc.1203859
    52 sg:pub.10.1038/sj.onc.1203977
    53 sg:pub.10.1038/sj.onc.1204475
    54 sg:pub.10.1038/sj.onc.1205004
    55 sg:pub.10.1038/sj.onc.1205150
    56 sg:pub.10.1038/sj.onc.1207646
    57 sg:pub.10.1038/sj.onc.1207650
    58 sg:pub.10.1038/sj.onc.1208327
    59 sg:pub.10.1038/sj.onc.1210201
    60 https://app.dimensions.ai/details/publication/pub.1074673343
    61 https://app.dimensions.ai/details/publication/pub.1074776556
    62 https://app.dimensions.ai/details/publication/pub.1077608194
    63 https://app.dimensions.ai/details/publication/pub.1078975891
    64 https://app.dimensions.ai/details/publication/pub.1082483991
    65 https://app.dimensions.ai/details/publication/pub.1082671742
    66 https://app.dimensions.ai/details/publication/pub.1082678010
    67 https://app.dimensions.ai/details/publication/pub.1082775305
    68 https://app.dimensions.ai/details/publication/pub.1083350373
    69 https://doi.org/10.1002/1097-4652(2000)9999:9999<000::aid-jcp1033>3.0.co;2-8
    70 https://doi.org/10.1002/humu.21374
    71 https://doi.org/10.1002/ijc.1595
    72 https://doi.org/10.1002/ijc.21766
    73 https://doi.org/10.1002/j.1460-2075.1991.tb07836.x
    74 https://doi.org/10.1002/jcb.10358
    75 https://doi.org/10.1002/path.2277
    76 https://doi.org/10.1016/0006-291x(89)92316-4
    77 https://doi.org/10.1016/0006-2952(95)00219-p
    78 https://doi.org/10.1016/0092-8674(86)90564-7
    79 https://doi.org/10.1016/0092-8674(91)90363-4
    80 https://doi.org/10.1016/0092-8674(94)90318-2
    81 https://doi.org/10.1016/j.ccr.2004.05.032
    82 https://doi.org/10.1016/j.ccr.2004.07.003
    83 https://doi.org/10.1016/j.ccr.2009.10.014
    84 https://doi.org/10.1016/j.cell.2006.02.025
    85 https://doi.org/10.1016/j.cell.2009.11.007
    86 https://doi.org/10.1016/j.devcel.2004.06.001
    87 https://doi.org/10.1016/j.devcel.2004.06.015
    88 https://doi.org/10.1016/j.devcel.2008.05.009
    89 https://doi.org/10.1016/j.tcb.2009.07.002
    90 https://doi.org/10.1016/j.tibs.2003.09.001
    91 https://doi.org/10.1016/s0002-9440(10)62323-1
    92 https://doi.org/10.1016/s0002-9440(10)63689-9
    93 https://doi.org/10.1016/s0006-291x(05)81187-8
    94 https://doi.org/10.1016/s0092-8674(01)00567-0
    95 https://doi.org/10.1016/s0140-6736(05)78259-3
    96 https://doi.org/10.1016/s0896-6273(00)80466-3
    97 https://doi.org/10.1016/s0896-6273(03)00493-8
    98 https://doi.org/10.1016/s0898-6568(99)00060-1
    99 https://doi.org/10.1016/s0955-0674(00)00251-9
    100 https://doi.org/10.1016/s0955-0674(03)00096-6
    101 https://doi.org/10.1016/s0962-8924(03)00104-1
    102 https://doi.org/10.1016/s0962-8924(98)01359-2
    103 https://doi.org/10.1016/s1097-2765(01)00261-1
    104 https://doi.org/10.1016/s1097-2765(01)00378-1
    105 https://doi.org/10.1016/s1097-2765(02)00439-2
    106 https://doi.org/10.1016/s1535-6108(03)00085-0
    107 https://doi.org/10.1038/sj.emboj.7600243
    108 https://doi.org/10.1038/sj.emboj.7600396
    109 https://doi.org/10.1042/bj20091448
    110 https://doi.org/10.1073/pnas.0306068101
    111 https://doi.org/10.1073/pnas.0403412101
    112 https://doi.org/10.1073/pnas.0508156103
    113 https://doi.org/10.1073/pnas.0508776103
    114 https://doi.org/10.1073/pnas.0702555104
    115 https://doi.org/10.1073/pnas.0707270105
    116 https://doi.org/10.1073/pnas.0707498104
    117 https://doi.org/10.1073/pnas.88.16.7001
    118 https://doi.org/10.1073/pnas.94.25.13868
    119 https://doi.org/10.1073/pnas.98.1.247
    120 https://doi.org/10.1074/jbc.270.46.27780
    121 https://doi.org/10.1074/jbc.271.22.13116
    122 https://doi.org/10.1074/jbc.273.30.18793
    123 https://doi.org/10.1074/jbc.273.50.33714
    124 https://doi.org/10.1074/jbc.275.15.10772
    125 https://doi.org/10.1074/jbc.m003597200
    126 https://doi.org/10.1074/jbc.m107551200
    127 https://doi.org/10.1074/jbc.m110.106435
    128 https://doi.org/10.1074/jbc.m110.134031
    129 https://doi.org/10.1074/jbc.m210656200
    130 https://doi.org/10.1074/jbc.m302116200
    131 https://doi.org/10.1074/jbc.m407769200
    132 https://doi.org/10.1074/jbc.m410012200
    133 https://doi.org/10.1074/jbc.m512298200
    134 https://doi.org/10.1074/jbc.m702573200
    135 https://doi.org/10.1074/jbc.m800186200
    136 https://doi.org/10.1074/jbc.m800727200
    137 https://doi.org/10.1074/jbc.m805916200
    138 https://doi.org/10.1083/jcb.123.1.223
    139 https://doi.org/10.1083/jcb.149.7.1419
    140 https://doi.org/10.1083/jcb.150.6.1375
    141 https://doi.org/10.1083/jcb.200605114
    142 https://doi.org/10.1083/jcb.200701086
    143 https://doi.org/10.1083/jcb.200806076
    144 https://doi.org/10.1083/jcb.200901129
    145 https://doi.org/10.1091/mbc.9.8.2185
    146 https://doi.org/10.1091/mbc.e06-08-0674
    147 https://doi.org/10.1091/mbc.e06-09-0823
    148 https://doi.org/10.1091/mbc.e08-09-0969
    149 https://doi.org/10.1093/carcin/bgh227
    150 https://doi.org/10.1093/emboj/16.10.2634
    151 https://doi.org/10.1096/fj.04-1535fje
    152 https://doi.org/10.1097/01.asn.0000130568.53923.fd
    153 https://doi.org/10.1101/gad.11.24.3341
    154 https://doi.org/10.1101/gad.242602
    155 https://doi.org/10.1111/j.1600-0854.2005.00290.x
    156 https://doi.org/10.1126/science.1072682
    157 https://doi.org/10.1126/science.1161431
    158 https://doi.org/10.1126/science.1162783
    159 https://doi.org/10.1126/science.1846706
    160 https://doi.org/10.1126/science.276.5309.60
    161 https://doi.org/10.1126/scisignal.2000643
    162 https://doi.org/10.1128/mcb.02253-05
    163 https://doi.org/10.1128/mcb.11.12.5954
    164 https://doi.org/10.1128/mcb.19.3.1784
    165 https://doi.org/10.1128/mcb.20.22.8513-8525.2000
    166 https://doi.org/10.1128/mcb.22.4.1060-1072.2002
    167 https://doi.org/10.1128/mcb.24.23.10328-10339.2004
    168 https://doi.org/10.1128/mcb.25.10.3982-3996.2005
    169 https://doi.org/10.1152/ajprenal.00451.2003
    170 https://doi.org/10.1158/0008-5472.can-03-2383
    171 https://doi.org/10.1158/0008-5472.can-05-2827
    172 https://doi.org/10.1158/0008-5472.can-08-1688
    173 https://doi.org/10.1158/0008-5472.can-08-2148
    174 https://doi.org/10.1158/0008-5472.can-10-0145
    175 https://doi.org/10.1158/1078-0432.ccr-10-0106
    176 https://doi.org/10.1161/hh0102.102756
    177 https://doi.org/10.1172/jci38075
    178 https://doi.org/10.1172/jci39104
    179 https://doi.org/10.1182/blood-2004-07-2885
    180 https://doi.org/10.1242/jcs.030197
    181 https://doi.org/10.4161/cc.4.3.1519
    182 schema:datePublished 2010-12
    183 schema:datePublishedReg 2010-12-01
    184 schema:description The MET tyrosine kinase receptor (also known as the HGF receptor) promotes tissue remodelling, which underlies developmental morphogenesis, wound repair, organ homeostasis and cancer metastasis, by integrating growth, survival and migration cues in response to environmental stimuli or cell-autonomous perturbations. The versatility of MET-mediated biological responses is sustained by qualitative and quantitative signal modulation. Qualitative mechanisms include the engagement of dedicated signal transducers and the subcellular compartmentalization of MET signalling pathways, whereas quantitative regulation involves MET partnering with adaptor amplifiers or being degraded through the shedding of its extracellular domain or through intracellular ubiquitylation. Controlled activation of MET signalling can be exploited in regenerative medicine, whereas MET inhibition might slow down tumour progression.
    185 schema:genre research_article
    186 schema:inLanguage en
    187 schema:isAccessibleForFree true
    188 schema:isPartOf N1e4e5a81187a4806aebff0bef4af48c5
    189 N85d5b0393b794837bcfee2d07e2b31fc
    190 sg:journal.1023609
    191 schema:name MET signalling: principles and functions in development, organ regeneration and cancer
    192 schema:pagination 834
    193 schema:productId N3846c5f7c6774b598e6710156bf8b031
    194 N5167c0937c9b4be882e91f4d297601c6
    195 N55d6b68ae07a4be880c2f51e0e08470b
    196 N80597b7e2d9b499ca2a8b7ab2a49b2b6
    197 Naa6a72101c6046299ecb4b66983a530a
    198 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002993405
    199 https://doi.org/10.1038/nrm3012
    200 schema:sdDatePublished 2019-04-11T11:00
    201 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    202 schema:sdPublisher N3513d8db08d84d1c9654acca4f85257b
    203 schema:url https://www.nature.com/articles/nrm3012
    204 sgo:license sg:explorer/license/
    205 sgo:sdDataset articles
    206 rdf:type schema:ScholarlyArticle
    207 N1150787ffcb846d387e9ca58d911e133 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    208 schema:name Humans
    209 rdf:type schema:DefinedTerm
    210 N1e4e5a81187a4806aebff0bef4af48c5 schema:volumeNumber 11
    211 rdf:type schema:PublicationVolume
    212 N3513d8db08d84d1c9654acca4f85257b schema:name Springer Nature - SN SciGraph project
    213 rdf:type schema:Organization
    214 N3664ab74e18b43ecbb555161f7b34062 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    215 schema:name Neoplasms
    216 rdf:type schema:DefinedTerm
    217 N3846c5f7c6774b598e6710156bf8b031 schema:name readcube_id
    218 schema:value 0e41818b4179ba8d1492b4587429eeff1ee774fc3e7a4d3c7288668dd49692d8
    219 rdf:type schema:PropertyValue
    220 N44cddc01dcd34eb8bce6be32b9cf2a0f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    221 schema:name Animal Structures
    222 rdf:type schema:DefinedTerm
    223 N4ae85f6d787f47fbb2ce6a5b4b0e8bae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    224 schema:name Regeneration
    225 rdf:type schema:DefinedTerm
    226 N5167c0937c9b4be882e91f4d297601c6 schema:name dimensions_id
    227 schema:value pub.1002993405
    228 rdf:type schema:PropertyValue
    229 N5529c87593cf42f2ab2932e39094d50a rdf:first sg:person.0772247030.82
    230 rdf:rest Nc0e6d0865f3545b798ab3364bf38aa20
    231 N55d6b68ae07a4be880c2f51e0e08470b schema:name pubmed_id
    232 schema:value 21102609
    233 rdf:type schema:PropertyValue
    234 N6371faa688ea447d828f8963cb13a9a6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    235 schema:name Models, Biological
    236 rdf:type schema:DefinedTerm
    237 N7e1279352646466ea369d06221798efa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    238 schema:name Growth and Development
    239 rdf:type schema:DefinedTerm
    240 N80597b7e2d9b499ca2a8b7ab2a49b2b6 schema:name doi
    241 schema:value 10.1038/nrm3012
    242 rdf:type schema:PropertyValue
    243 N85d5b0393b794837bcfee2d07e2b31fc schema:issueNumber 12
    244 rdf:type schema:PublicationIssue
    245 Na58a3291aba7463a9cbdf07377c8652a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    246 schema:name Animals
    247 rdf:type schema:DefinedTerm
    248 Naa6a72101c6046299ecb4b66983a530a schema:name nlm_unique_id
    249 schema:value 100962782
    250 rdf:type schema:PropertyValue
    251 Naeb67a64a4b7497aa14091c4e9939ff9 rdf:first sg:person.01070076557.01
    252 rdf:rest rdf:nil
    253 Nc0e6d0865f3545b798ab3364bf38aa20 rdf:first sg:person.01274134276.83
    254 rdf:rest Naeb67a64a4b7497aa14091c4e9939ff9
    255 Nd522dca38ef64085a93084d10628aacc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    256 schema:name Proto-Oncogene Proteins c-met
    257 rdf:type schema:DefinedTerm
    258 Ndbb7c91169e049b5aa14de7885acf98c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    259 schema:name Signal Transduction
    260 rdf:type schema:DefinedTerm
    261 Nf781647fb5fe45aab224d424b302c40d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    262 schema:name Models, Molecular
    263 rdf:type schema:DefinedTerm
    264 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    265 schema:name Biological Sciences
    266 rdf:type schema:DefinedTerm
    267 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    268 schema:name Biochemistry and Cell Biology
    269 rdf:type schema:DefinedTerm
    270 sg:journal.1023609 schema:issn 1471-0072
    271 1471-0080
    272 schema:name Nature Reviews Molecular Cell Biology
    273 rdf:type schema:Periodical
    274 sg:person.01070076557.01 schema:affiliation https://www.grid.ac/institutes/grid.419555.9
    275 schema:familyName Comoglio
    276 schema:givenName Paolo M.
    277 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070076557.01
    278 rdf:type schema:Person
    279 sg:person.01274134276.83 schema:affiliation https://www.grid.ac/institutes/grid.419555.9
    280 schema:familyName Bertotti
    281 schema:givenName Andrea
    282 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274134276.83
    283 rdf:type schema:Person
    284 sg:person.0772247030.82 schema:affiliation https://www.grid.ac/institutes/grid.419555.9
    285 schema:familyName Trusolino
    286 schema:givenName Livio
    287 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772247030.82
    288 rdf:type schema:Person
    289 sg:pub.10.1038/327239a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002266258
    290 https://doi.org/10.1038/327239a0
    291 rdf:type schema:CreativeWork
    292 sg:pub.10.1038/339155a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018635692
    293 https://doi.org/10.1038/339155a0
    294 rdf:type schema:CreativeWork
    295 sg:pub.10.1038/342440a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009687593
    296 https://doi.org/10.1038/342440a0
    297 rdf:type schema:CreativeWork
    298 sg:pub.10.1038/34657 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052561190
    299 https://doi.org/10.1038/34657
    300 rdf:type schema:CreativeWork
    301 sg:pub.10.1038/373699a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040388169
    302 https://doi.org/10.1038/373699a0
    303 rdf:type schema:CreativeWork
    304 sg:pub.10.1038/373702a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045696614
    305 https://doi.org/10.1038/373702a0
    306 rdf:type schema:CreativeWork
    307 sg:pub.10.1038/376768a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013243841
    308 https://doi.org/10.1038/376768a0
    309 rdf:type schema:CreativeWork
    310 sg:pub.10.1038/384173a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032028837
    311 https://doi.org/10.1038/384173a0
    312 rdf:type schema:CreativeWork
    313 sg:pub.10.1038/416133a schema:sameAs https://app.dimensions.ai/details/publication/pub.1017601282
    314 https://doi.org/10.1038/416133a
    315 rdf:type schema:CreativeWork
    316 sg:pub.10.1038/416187a schema:sameAs https://app.dimensions.ai/details/publication/pub.1019096765
    317 https://doi.org/10.1038/416187a
    318 rdf:type schema:CreativeWork
    319 sg:pub.10.1038/5593 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032649050
    320 https://doi.org/10.1038/5593
    321 rdf:type schema:CreativeWork
    322 sg:pub.10.1038/nature03096 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051657854
    323 https://doi.org/10.1038/nature03096
    324 rdf:type schema:CreativeWork
    325 sg:pub.10.1038/nature04872 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003500438
    326 https://doi.org/10.1038/nature04872
    327 rdf:type schema:CreativeWork
    328 sg:pub.10.1038/nature07039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030873761
    329 https://doi.org/10.1038/nature07039
    330 rdf:type schema:CreativeWork
    331 sg:pub.10.1038/nature08910 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049800104
    332 https://doi.org/10.1038/nature08910
    333 rdf:type schema:CreativeWork
    334 sg:pub.10.1038/ncb843 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004186791
    335 https://doi.org/10.1038/ncb843
    336 rdf:type schema:CreativeWork
    337 sg:pub.10.1038/ng0597-68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035254306
    338 https://doi.org/10.1038/ng0597-68
    339 rdf:type schema:CreativeWork
    340 sg:pub.10.1038/ng1987 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032102166
    341 https://doi.org/10.1038/ng1987
    342 rdf:type schema:CreativeWork
    343 sg:pub.10.1038/nrc1695 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003902023
    344 https://doi.org/10.1038/nrc1695
    345 rdf:type schema:CreativeWork
    346 sg:pub.10.1038/nrc779 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007964460
    347 https://doi.org/10.1038/nrc779
    348 rdf:type schema:CreativeWork
    349 sg:pub.10.1038/nrc780 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024581782
    350 https://doi.org/10.1038/nrc780
    351 rdf:type schema:CreativeWork
    352 sg:pub.10.1038/nrd2289 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040589518
    353 https://doi.org/10.1038/nrd2289
    354 rdf:type schema:CreativeWork
    355 sg:pub.10.1038/nrd2530 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006672418
    356 https://doi.org/10.1038/nrd2530
    357 rdf:type schema:CreativeWork
    358 sg:pub.10.1038/nrg1272 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018231980
    359 https://doi.org/10.1038/nrg1272
    360 rdf:type schema:CreativeWork
    361 sg:pub.10.1038/nrm1004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044326367
    362 https://doi.org/10.1038/nrm1004
    363 rdf:type schema:CreativeWork
    364 sg:pub.10.1038/nrm1261 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036162157
    365 https://doi.org/10.1038/nrm1261
    366 rdf:type schema:CreativeWork
    367 sg:pub.10.1038/nrm2455 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012647427
    368 https://doi.org/10.1038/nrm2455
    369 rdf:type schema:CreativeWork
    370 sg:pub.10.1038/nrm2523 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032396036
    371 https://doi.org/10.1038/nrm2523
    372 rdf:type schema:CreativeWork
    373 sg:pub.10.1038/nrm2636 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023434470
    374 https://doi.org/10.1038/nrm2636
    375 rdf:type schema:CreativeWork
    376 sg:pub.10.1038/nrm2748 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015441819
    377 https://doi.org/10.1038/nrm2748
    378 rdf:type schema:CreativeWork
    379 sg:pub.10.1038/nrm2847 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037228915
    380 https://doi.org/10.1038/nrm2847
    381 rdf:type schema:CreativeWork
    382 sg:pub.10.1038/sj.bjc.6603884 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041940900
    383 https://doi.org/10.1038/sj.bjc.6603884
    384 rdf:type schema:CreativeWork
    385 sg:pub.10.1038/sj.cdd.4402080 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021721025
    386 https://doi.org/10.1038/sj.cdd.4402080
    387 rdf:type schema:CreativeWork
    388 sg:pub.10.1038/sj.cr.7290264 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014667344
    389 https://doi.org/10.1038/sj.cr.7290264
    390 rdf:type schema:CreativeWork
    391 sg:pub.10.1038/sj.onc.1202607 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027189119
    392 https://doi.org/10.1038/sj.onc.1202607
    393 rdf:type schema:CreativeWork
    394 sg:pub.10.1038/sj.onc.1203198 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046015028
    395 https://doi.org/10.1038/sj.onc.1203198
    396 rdf:type schema:CreativeWork
    397 sg:pub.10.1038/sj.onc.1203514 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051008900
    398 https://doi.org/10.1038/sj.onc.1203514
    399 rdf:type schema:CreativeWork
    400 sg:pub.10.1038/sj.onc.1203859 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017661502
    401 https://doi.org/10.1038/sj.onc.1203859
    402 rdf:type schema:CreativeWork
    403 sg:pub.10.1038/sj.onc.1203977 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049903632
    404 https://doi.org/10.1038/sj.onc.1203977
    405 rdf:type schema:CreativeWork
    406 sg:pub.10.1038/sj.onc.1204475 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040457827
    407 https://doi.org/10.1038/sj.onc.1204475
    408 rdf:type schema:CreativeWork
    409 sg:pub.10.1038/sj.onc.1205004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023491583
    410 https://doi.org/10.1038/sj.onc.1205004
    411 rdf:type schema:CreativeWork
    412 sg:pub.10.1038/sj.onc.1205150 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048836587
    413 https://doi.org/10.1038/sj.onc.1205150
    414 rdf:type schema:CreativeWork
    415 sg:pub.10.1038/sj.onc.1207646 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030876928
    416 https://doi.org/10.1038/sj.onc.1207646
    417 rdf:type schema:CreativeWork
    418 sg:pub.10.1038/sj.onc.1207650 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033545030
    419 https://doi.org/10.1038/sj.onc.1207650
    420 rdf:type schema:CreativeWork
    421 sg:pub.10.1038/sj.onc.1208327 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051138612
    422 https://doi.org/10.1038/sj.onc.1208327
    423 rdf:type schema:CreativeWork
    424 sg:pub.10.1038/sj.onc.1210201 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048606887
    425 https://doi.org/10.1038/sj.onc.1210201
    426 rdf:type schema:CreativeWork
    427 https://app.dimensions.ai/details/publication/pub.1074673343 schema:CreativeWork
    428 https://app.dimensions.ai/details/publication/pub.1074776556 schema:CreativeWork
    429 https://app.dimensions.ai/details/publication/pub.1077608194 schema:CreativeWork
    430 https://app.dimensions.ai/details/publication/pub.1078975891 schema:CreativeWork
    431 https://app.dimensions.ai/details/publication/pub.1082483991 schema:CreativeWork
    432 https://app.dimensions.ai/details/publication/pub.1082671742 schema:CreativeWork
    433 https://app.dimensions.ai/details/publication/pub.1082678010 schema:CreativeWork
    434 https://app.dimensions.ai/details/publication/pub.1082775305 schema:CreativeWork
    435 https://app.dimensions.ai/details/publication/pub.1083350373 schema:CreativeWork
    436 https://doi.org/10.1002/1097-4652(2000)9999:9999<000::aid-jcp1033>3.0.co;2-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002040972
    437 rdf:type schema:CreativeWork
    438 https://doi.org/10.1002/humu.21374 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016333807
    439 rdf:type schema:CreativeWork
    440 https://doi.org/10.1002/ijc.1595 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019793540
    441 rdf:type schema:CreativeWork
    442 https://doi.org/10.1002/ijc.21766 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012791881
    443 rdf:type schema:CreativeWork
    444 https://doi.org/10.1002/j.1460-2075.1991.tb07836.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1077206922
    445 rdf:type schema:CreativeWork
    446 https://doi.org/10.1002/jcb.10358 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015355049
    447 rdf:type schema:CreativeWork
    448 https://doi.org/10.1002/path.2277 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010508721
    449 rdf:type schema:CreativeWork
    450 https://doi.org/10.1016/0006-291x(89)92316-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028656274
    451 rdf:type schema:CreativeWork
    452 https://doi.org/10.1016/0006-2952(95)00219-p schema:sameAs https://app.dimensions.ai/details/publication/pub.1045433594
    453 rdf:type schema:CreativeWork
    454 https://doi.org/10.1016/0092-8674(86)90564-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030560653
    455 rdf:type schema:CreativeWork
    456 https://doi.org/10.1016/0092-8674(91)90363-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043779064
    457 rdf:type schema:CreativeWork
    458 https://doi.org/10.1016/0092-8674(94)90318-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009238656
    459 rdf:type schema:CreativeWork
    460 https://doi.org/10.1016/j.ccr.2004.05.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018217404
    461 rdf:type schema:CreativeWork
    462 https://doi.org/10.1016/j.ccr.2004.07.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012945779
    463 rdf:type schema:CreativeWork
    464 https://doi.org/10.1016/j.ccr.2009.10.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029310321
    465 rdf:type schema:CreativeWork
    466 https://doi.org/10.1016/j.cell.2006.02.025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000172640
    467 rdf:type schema:CreativeWork
    468 https://doi.org/10.1016/j.cell.2009.11.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017006433
    469 rdf:type schema:CreativeWork
    470 https://doi.org/10.1016/j.devcel.2004.06.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035846094
    471 rdf:type schema:CreativeWork
    472 https://doi.org/10.1016/j.devcel.2004.06.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019410848
    473 rdf:type schema:CreativeWork
    474 https://doi.org/10.1016/j.devcel.2008.05.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008314667
    475 rdf:type schema:CreativeWork
    476 https://doi.org/10.1016/j.tcb.2009.07.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041805638
    477 rdf:type schema:CreativeWork
    478 https://doi.org/10.1016/j.tibs.2003.09.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013808314
    479 rdf:type schema:CreativeWork
    480 https://doi.org/10.1016/s0002-9440(10)62323-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030900957
    481 rdf:type schema:CreativeWork
    482 https://doi.org/10.1016/s0002-9440(10)63689-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049830806
    483 rdf:type schema:CreativeWork
    484 https://doi.org/10.1016/s0006-291x(05)81187-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001445662
    485 rdf:type schema:CreativeWork
    486 https://doi.org/10.1016/s0092-8674(01)00567-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043857082
    487 rdf:type schema:CreativeWork
    488 https://doi.org/10.1016/s0140-6736(05)78259-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005963147
    489 rdf:type schema:CreativeWork
    490 https://doi.org/10.1016/s0896-6273(00)80466-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006228430
    491 rdf:type schema:CreativeWork
    492 https://doi.org/10.1016/s0896-6273(03)00493-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019221689
    493 rdf:type schema:CreativeWork
    494 https://doi.org/10.1016/s0898-6568(99)00060-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031991548
    495 rdf:type schema:CreativeWork
    496 https://doi.org/10.1016/s0955-0674(00)00251-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030166395
    497 rdf:type schema:CreativeWork
    498 https://doi.org/10.1016/s0955-0674(03)00096-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010382040
    499 rdf:type schema:CreativeWork
    500 https://doi.org/10.1016/s0962-8924(03)00104-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016623110
    501 rdf:type schema:CreativeWork
    502 https://doi.org/10.1016/s0962-8924(98)01359-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033287811
    503 rdf:type schema:CreativeWork
    504 https://doi.org/10.1016/s1097-2765(01)00261-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039529656
    505 rdf:type schema:CreativeWork
    506 https://doi.org/10.1016/s1097-2765(01)00378-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031065445
    507 rdf:type schema:CreativeWork
    508 https://doi.org/10.1016/s1097-2765(02)00439-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053474783
    509 rdf:type schema:CreativeWork
    510 https://doi.org/10.1016/s1535-6108(03)00085-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044383357
    511 rdf:type schema:CreativeWork
    512 https://doi.org/10.1038/sj.emboj.7600243 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052262305
    513 rdf:type schema:CreativeWork
    514 https://doi.org/10.1038/sj.emboj.7600396 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001191060
    515 rdf:type schema:CreativeWork
    516 https://doi.org/10.1042/bj20091448 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008162532
    517 rdf:type schema:CreativeWork
    518 https://doi.org/10.1073/pnas.0306068101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026992033
    519 rdf:type schema:CreativeWork
    520 https://doi.org/10.1073/pnas.0403412101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046591274
    521 rdf:type schema:CreativeWork
    522 https://doi.org/10.1073/pnas.0508156103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053298396
    523 rdf:type schema:CreativeWork
    524 https://doi.org/10.1073/pnas.0508776103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050433384
    525 rdf:type schema:CreativeWork
    526 https://doi.org/10.1073/pnas.0702555104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010323142
    527 rdf:type schema:CreativeWork
    528 https://doi.org/10.1073/pnas.0707270105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048800685
    529 rdf:type schema:CreativeWork
    530 https://doi.org/10.1073/pnas.0707498104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036732228
    531 rdf:type schema:CreativeWork
    532 https://doi.org/10.1073/pnas.88.16.7001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010182145
    533 rdf:type schema:CreativeWork
    534 https://doi.org/10.1073/pnas.94.25.13868 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014411971
    535 rdf:type schema:CreativeWork
    536 https://doi.org/10.1073/pnas.98.1.247 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034658483
    537 rdf:type schema:CreativeWork
    538 https://doi.org/10.1074/jbc.270.46.27780 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020892755
    539 rdf:type schema:CreativeWork
    540 https://doi.org/10.1074/jbc.271.22.13116 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014432779
    541 rdf:type schema:CreativeWork
    542 https://doi.org/10.1074/jbc.273.30.18793 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022148973
    543 rdf:type schema:CreativeWork
    544 https://doi.org/10.1074/jbc.273.50.33714 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006950258
    545 rdf:type schema:CreativeWork
    546 https://doi.org/10.1074/jbc.275.15.10772 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029368156
    547 rdf:type schema:CreativeWork
    548 https://doi.org/10.1074/jbc.m003597200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023018536
    549 rdf:type schema:CreativeWork
    550 https://doi.org/10.1074/jbc.m107551200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027334376
    551 rdf:type schema:CreativeWork
    552 https://doi.org/10.1074/jbc.m110.106435 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037022518
    553 rdf:type schema:CreativeWork
    554 https://doi.org/10.1074/jbc.m110.134031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052151458
    555 rdf:type schema:CreativeWork
    556 https://doi.org/10.1074/jbc.m210656200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042583933
    557 rdf:type schema:CreativeWork
    558 https://doi.org/10.1074/jbc.m302116200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024926716
    559 rdf:type schema:CreativeWork
    560 https://doi.org/10.1074/jbc.m407769200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025485527
    561 rdf:type schema:CreativeWork
    562 https://doi.org/10.1074/jbc.m410012200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018088912
    563 rdf:type schema:CreativeWork
    564 https://doi.org/10.1074/jbc.m512298200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015781559
    565 rdf:type schema:CreativeWork
    566 https://doi.org/10.1074/jbc.m702573200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033163137
    567 rdf:type schema:CreativeWork
    568 https://doi.org/10.1074/jbc.m800186200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013469916
    569 rdf:type schema:CreativeWork
    570 https://doi.org/10.1074/jbc.m800727200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049581993
    571 rdf:type schema:CreativeWork
    572 https://doi.org/10.1074/jbc.m805916200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006610999
    573 rdf:type schema:CreativeWork
    574 https://doi.org/10.1083/jcb.123.1.223 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021041037
    575 rdf:type schema:CreativeWork
    576 https://doi.org/10.1083/jcb.149.7.1419 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027555981
    577 rdf:type schema:CreativeWork
    578 https://doi.org/10.1083/jcb.150.6.1375 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007749916
    579 rdf:type schema:CreativeWork
    580 https://doi.org/10.1083/jcb.200605114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016986122
    581 rdf:type schema:CreativeWork
    582 https://doi.org/10.1083/jcb.200701086 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026928336
    583 rdf:type schema:CreativeWork
    584 https://doi.org/10.1083/jcb.200806076 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043877787
    585 rdf:type schema:CreativeWork
    586 https://doi.org/10.1083/jcb.200901129 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002220904
    587 rdf:type schema:CreativeWork
    588 https://doi.org/10.1091/mbc.9.8.2185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043136045
    589 rdf:type schema:CreativeWork
    590 https://doi.org/10.1091/mbc.e06-08-0674 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031691994
    591 rdf:type schema:CreativeWork
    592 https://doi.org/10.1091/mbc.e06-09-0823 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025595648
    593 rdf:type schema:CreativeWork
    594 https://doi.org/10.1091/mbc.e08-09-0969 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041112390
    595 rdf:type schema:CreativeWork
    596 https://doi.org/10.1093/carcin/bgh227 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004227312
    597 rdf:type schema:CreativeWork
    598 https://doi.org/10.1093/emboj/16.10.2634 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009144692
    599 rdf:type schema:CreativeWork
    600 https://doi.org/10.1096/fj.04-1535fje schema:sameAs https://app.dimensions.ai/details/publication/pub.1040662362
    601 rdf:type schema:CreativeWork
    602 https://doi.org/10.1097/01.asn.0000130568.53923.fd schema:sameAs https://app.dimensions.ai/details/publication/pub.1060319638
    603 rdf:type schema:CreativeWork
    604 https://doi.org/10.1101/gad.11.24.3341 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033218196
    605 rdf:type schema:CreativeWork
    606 https://doi.org/10.1101/gad.242602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048510702
    607 rdf:type schema:CreativeWork
    608 https://doi.org/10.1111/j.1600-0854.2005.00290.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1018353378
    609 rdf:type schema:CreativeWork
    610 https://doi.org/10.1126/science.1072682 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005671466
    611 rdf:type schema:CreativeWork
    612 https://doi.org/10.1126/science.1161431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035033278
    613 rdf:type schema:CreativeWork
    614 https://doi.org/10.1126/science.1162783 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062458588
    615 rdf:type schema:CreativeWork
    616 https://doi.org/10.1126/science.1846706 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062509911
    617 rdf:type schema:CreativeWork
    618 https://doi.org/10.1126/science.276.5309.60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062556261
    619 rdf:type schema:CreativeWork
    620 https://doi.org/10.1126/scisignal.2000643 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062682180
    621 rdf:type schema:CreativeWork
    622 https://doi.org/10.1128/mcb.02253-05 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004880527
    623 rdf:type schema:CreativeWork
    624 https://doi.org/10.1128/mcb.11.12.5954 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025596508
    625 rdf:type schema:CreativeWork
    626 https://doi.org/10.1128/mcb.19.3.1784 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052260320
    627 rdf:type schema:CreativeWork
    628 https://doi.org/10.1128/mcb.20.22.8513-8525.2000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050294945
    629 rdf:type schema:CreativeWork
    630 https://doi.org/10.1128/mcb.22.4.1060-1072.2002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036812375
    631 rdf:type schema:CreativeWork
    632 https://doi.org/10.1128/mcb.24.23.10328-10339.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034912857
    633 rdf:type schema:CreativeWork
    634 https://doi.org/10.1128/mcb.25.10.3982-3996.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037103664
    635 rdf:type schema:CreativeWork
    636 https://doi.org/10.1152/ajprenal.00451.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050500132
    637 rdf:type schema:CreativeWork
    638 https://doi.org/10.1158/0008-5472.can-03-2383 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032451222
    639 rdf:type schema:CreativeWork
    640 https://doi.org/10.1158/0008-5472.can-05-2827 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040314736
    641 rdf:type schema:CreativeWork
    642 https://doi.org/10.1158/0008-5472.can-08-1688 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046143763
    643 rdf:type schema:CreativeWork
    644 https://doi.org/10.1158/0008-5472.can-08-2148 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048161861
    645 rdf:type schema:CreativeWork
    646 https://doi.org/10.1158/0008-5472.can-10-0145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050520970
    647 rdf:type schema:CreativeWork
    648 https://doi.org/10.1158/1078-0432.ccr-10-0106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026911925
    649 rdf:type schema:CreativeWork
    650 https://doi.org/10.1161/hh0102.102756 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039844636
    651 rdf:type schema:CreativeWork
    652 https://doi.org/10.1172/jci38075 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043159224
    653 rdf:type schema:CreativeWork
    654 https://doi.org/10.1172/jci39104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026879393
    655 rdf:type schema:CreativeWork
    656 https://doi.org/10.1182/blood-2004-07-2885 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025396562
    657 rdf:type schema:CreativeWork
    658 https://doi.org/10.1242/jcs.030197 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003112306
    659 rdf:type schema:CreativeWork
    660 https://doi.org/10.4161/cc.4.3.1519 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072298227
    661 rdf:type schema:CreativeWork
    662 https://www.grid.ac/institutes/grid.419555.9 schema:alternateName Candiolo Cancer Institute
    663 schema:name Institute for Cancer Research and Treatment (IRCC), University of Torino Medical School, 10060 Candiolo, Torino, Italy.
    664 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...