Mechanisms of Polycomb gene silencing: knowns and unknowns View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-10

AUTHORS

Jeffrey A Simon, Robert E Kingston

ABSTRACT

Polycomb proteins form chromatin-modifying complexes that implement transcriptional silencing in higher eukaryotes. Hundreds of genes are silenced by Polycomb proteins, including dozens of genes that encode crucial developmental regulators in organisms ranging from plants to humans. Two main families of complexes, called Polycomb repressive complex 1 (PRC1) and PRC2, are targeted to repressed regions. Recent studies have advanced our understanding of these complexes, including their potential mechanisms of gene silencing, the roles of chromatin modifications, their means of delivery to target genes and the functional distinctions among variant complexes. Emerging concepts include the existence of a Polycomb barrier to transcription elongation and the involvement of non-coding RNAs in the targeting of Polycomb complexes. These findings have an impact on the epigenetic programming of gene expression in many biological systems. More... »

PAGES

697-708

References to SciGraph publications

  • 2008-09. Epigenetic transcriptional repression of cellular genes by a viral SET protein in NATURE CELL BIOLOGY
  • 2006-06. Genome-wide analysis of Polycomb targets in Drosophila melanogaster in NATURE GENETICS
  • 2006-08. Probing long-distance regulatory interactions in the Drosophila melanogaster bithorax complex using Dam identification in NATURE GENETICS
  • 2007-08. Genomic biology: The epigenomic era opens in NATURE
  • 1985-07. A group of genes controlling the spatial expression of the bithorax complex in Drosophila in NATURE
  • 2006-06. Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster in NATURE GENETICS
  • 2006-11. Polycomb silencers control cell fate, development and cancer in NATURE REVIEWS CANCER
  • 2005-03. Recruitment of Drosophila Polycomb group proteins to chromatin by DSP1 in NATURE
  • 2004-10. Role of histone H2A ubiquitination in Polycomb silencing in NATURE
  • 2006-05. Polycomb complexes repress developmental regulators in murine embryonic stem cells in NATURE
  • 2004-02. Modulation of heat shock gene expression by the TAC1 chromatin-modifying complex in NATURE CELL BIOLOGY
  • 2001-06. Mechanisms of transcriptional memory in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2008-06. Replacement of a Drosophila Polycomb response element core, and in situ analysis of its DNA motifs in MOLECULAR GENETICS AND GENOMICS
  • 2008-06. The nuclear organization of Polycomb/Trithorax group response elements in larval tissues of Drosophila melanogaster in CHROMOSOME RESEARCH
  • 2007-12. Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells in NATURE CELL BIOLOGY
  • 2002-02. Chromosomal silencing and localization are mediated by different domains of Xist RNA in NATURE GENETICS
  • 1978-12. A gene complex controlling segmentation in Drosophila in NATURE
  • 2006-09. Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2008-11. A model for transmission of the H3K27me3 epigenetic mark in NATURE CELL BIOLOGY
  • 1981-09. A gene product required for correct initiation of segmental determination in Drosophila in NATURE
  • 2001-08. General transcription factors bind promoters repressed by Polycomb group proteins in NATURE
  • 2001-08. A Drosophila Polycomb group complex includes Zeste and dTAFII proteins in NATURE
  • 1999-07. The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins in NATURE
  • 2004-05. Epigenetics in human disease and prospects for epigenetic therapy in NATURE
  • 2006-08. A genomic code for nucleosome positioning in NATURE
  • 2006-01. Epigenetic therapy of cancer: past, present and future in NATURE REVIEWS DRUG DISCOVERY
  • 2007-10. Polycomb response elements mediate the formation of chromosome higher-order structures in the bithorax complex in NATURE CELL BIOLOGY
  • 1989-02. In vivo binding pattern of a trans-regulator of homoeotic genes in Drosophila melanogaster in NATURE
  • 2008-05. An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors in NATURE GENETICS
  • 2007-01. Polycomb silencing mechanisms and the management of genomic programmes in NATURE REVIEWS GENETICS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrm2763

    DOI

    http://dx.doi.org/10.1038/nrm2763

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1004980736

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19738629


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