Protein tyrosine phosphatases: from genes, to function, to disease View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2006-11

AUTHORS

Nicholas K Tonks

ABSTRACT

The protein tyrosine phosphatase (PTP) superfamily of enzymes functions in a coordinated manner with protein tyrosine kinases to control signalling pathways that underlie a broad spectrum of fundamental physiological processes. In this review, I describe recent breakthroughs in our understanding of the role of the PTPs in the regulation of signal transduction and the aetiology of human disease. More... »

PAGES

833-846

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrm2039

    DOI

    http://dx.doi.org/10.1038/nrm2039

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1021713482

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/17057753


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