ILK, PINCH and parvin: the tIPP of integrin signalling View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2006-01

AUTHORS

Kyle R Legate, Eloi Montañez, Oliver Kudlacek, Reinhard Fässler

ABSTRACT

The ternary complex of integrin-linked kinase (ILK), PINCH and parvin functions as a signalling platform for integrins by interfacing with the actin cytoskeleton and many diverse signalling pathways. All these proteins have synergistic functions at focal adhesions, but recent work has indicated that these proteins might also have separate roles within a cell. They function as regulators of gene transcription or cell-cell adhesion. More... »

PAGES

20-31

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrm1789

    DOI

    http://dx.doi.org/10.1038/nrm1789

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1036759909

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/16493410


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