Developmental cell biology: The cell biology of neurogenesis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-10

AUTHORS

Magdalena Götz, Wieland B Huttner

ABSTRACT

During the development of the mammalian central nervous system, neural stem cells and their derivative progenitor cells generate neurons by asymmetric and symmetric divisions. The proliferation versus differentiation of these cells and the type of division are closely linked to their epithelial characteristics, notably, their apical-basal polarity and cell-cycle length. Here, we discuss how these features change during development from neuroepithelial to radial glial cells, and how this transition affects cell fate and neurogenesis. More... »

PAGES

777-788

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrm1739

    DOI

    http://dx.doi.org/10.1038/nrm1739

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1001699881

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/16314867


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