NF-κB regulation in the immune system View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-10

AUTHORS

Qiutang Li, Inder M Verma

ABSTRACT

The nuclear factor-kappaB (NF-kappaB)/REL family of transcription factors has a central role in coordinating the expression of a wide variety of genes that control immune responses. There has been intense scientific activity in the NF-kappaB field owing to the involvement of these factors in the activation and regulation of key molecules that are associated with diseases ranging from inflammation to cancer. In this review, we focus on our current understanding of NF-kappaB regulation and its role in the immune system and inflammatory diseases. We also discuss the role of NF-kappaB proteins as potential therapeutic targets in clinical applications. More... »

PAGES

725-734

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nri910

    DOI

    http://dx.doi.org/10.1038/nri910

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1027911236

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/12360211


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