Antibodies, viruses and vaccines View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-09

AUTHORS

Dennis R Burton

ABSTRACT

Neutralizing antibodies are crucial for vaccine-mediated protection against viral diseases. They probably act, in most cases, by blunting the infection, which is then resolved by cellular immunity. The protective effects of neutralizing antibodies can be achieved not only by neutralization of free virus particles, but also by several activities directed against infected cells. In certain instances, non-neutralizing antibodies contribute to protection. Several viruses, such as HIV, have evolved mechanisms to evade neutralizing-antibody responses, and these viruses present special challenges for vaccine design that are now being tackled. More... »

PAGES

706-713

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nri891

    DOI

    http://dx.doi.org/10.1038/nri891

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1018512919

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/12209139


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