Maintaining the norm: T-cell homeostasis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-08

AUTHORS

Stephen C Jameson

ABSTRACT

The persistence of naive and memory T cells has long been of interest to immunologists, but the factors that influence the survival and homeostasis of these subsets have remained obscure. In recent years, it has become evident that the homeostasis of both naive and memory T-cell pools is highly dynamic and tightly regulated by internal stimuli, including cytokines and self-peptide–MHC ligands for the T-cell receptor. These homeostatic mechanisms might have a vital influence on the capacity of the T-cell pool to respond to both foreign and self-antigens. More... »

PAGES

547-556

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nri853

    DOI

    http://dx.doi.org/10.1038/nri853

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1015746364

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/12154374


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