Spinning molecular immunology into successful immunotherapy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-04

AUTHORS

Drew M Pardoll

ABSTRACT

Until recently, immunotherapies have been of limited success, particularly against cancer. However, recent insights into the cells, molecules and signalling pathways that regulate immune responsiveness are providing new approaches for immunotherapy. In this article, I review some of the most promising molecular and cellular targets for immunotherapy and discuss approaches that use these targets to amplify immune responses and potentially break antigen-specific tolerance. These strategies provide a blueprint for the development of successful immunotherapy over the next decade. More... »

PAGES

227-238

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nri774

DOI

http://dx.doi.org/10.1038/nri774

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1045044815

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12001994


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