Diversity and dialogue in immunity to helminths View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-06

AUTHORS

Judith E. Allen, Rick M. Maizels

ABSTRACT

The vertebrate immune system has evolved in concert with a broad range of infectious agents, including ubiquitous helminth (worm) parasites. The constant pressure of helminth infections has been a powerful force in shaping not only how immunity is initiated and maintained, but also how the body self-regulates and controls untoward immune responses to minimize overall harm. In this Review, we discuss recent advances in defining the immune cell types and molecules that are mobilized in response to helminth infection. Finally, we more broadly consider how these immunological players are blended and regulated in order to accommodate persistent infection or to mount a vigorous protective response and achieve sterile immunity. More... »

PAGES

375

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nri2992

    DOI

    http://dx.doi.org/10.1038/nri2992

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1001673301

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/21610741


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