Immunological aspects of cancer chemotherapy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-01

AUTHORS

Laurence Zitvogel, Lionel Apetoh, François Ghiringhelli, Guido Kroemer

ABSTRACT

Accumulating evidence indicates that the innate and adaptive immune systems make a crucial contribution to the antitumour effects of conventional chemotherapy-based and radiotherapy-based cancer treatments. Moreover, the molecular and cellular bases of the immunogenicity of cell death that is induced by cytotoxic agents are being progressively unravelled, challenging the guidelines that currently govern the development of anticancer drugs. Here, we review the immunological aspects of conventional cancer treatments and propose that future successes in the fight against cancer will rely on the development and clinical application of combined chemo- and immunotherapies. More... »

PAGES

59

References to SciGraph publications

Journal

TITLE

Nature Reviews Immunology

ISSUE

1

VOLUME

8

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nri2216

    DOI

    http://dx.doi.org/10.1038/nri2216

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1044452926

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/18097448


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