Humanized mice in translational biomedical research View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-02

AUTHORS

Leonard D Shultz, Fumihiko Ishikawa, Dale L Greiner

ABSTRACT

The culmination of decades of research on humanized mice is leading to advances in our understanding of human haematopoiesis, innate and adaptive immunity, autoimmunity, infectious diseases, cancer biology and regenerative medicine. In this Review, we discuss the development of these new generations of humanized mice, how they will facilitate translational research in several biomedical disciplines and approaches to overcome the remaining limitations of these models. More... »

PAGES

118-130

References to SciGraph publications

  • 1983-02. A severe combined immunodeficiency mutation in the mouse in NATURE
  • 2006-12. HIV-1 infection and CD4 T cell depletion in the humanized Rag2-/-γc-/-(RAG-hu) mouse model in RETROVIROLOGY
  • 2003-07. Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells in NATURE MEDICINE
  • 1988-09. Transfer of a functional human immune system to mice with severe combined immunodeficiency in NATURE
  • 2006-04. From teratocarcinomas to embryonic stem cells and beyond: a history of embryonic stem cell research in NATURE REVIEWS GENETICS
  • 2005-08. Efficient engraftment of primary adult T-cell leukemia cells in newborn NOD/SCID/β2-microglobulinnull mice in LEUKEMIA
  • 1993-06. Transfer of Type 1 (insulin-dependent) diabetes mellitus associated autoimmunity to mice with severe combined immunodeficiency (SCID) in DIABETOLOGIA
  • 2005-12. Activated natural killer cells from patients with acute myeloid leukemia are cytotoxic against autologous leukemic blasts in NOD/SCID mice in LEUKEMIA
  • 1996-06. Angiostatin induces and sustains dormancy of human primary tumors in mice in NATURE MEDICINE
  • 1998-12. Xenotransplantation of human lymphoid malignancies is optimized in mice with multiple immunologic defects in LEUKEMIA
  • 2005-12. Biology of Normal and Acute Myeloid Leukemia Stem Cells in INTERNATIONAL JOURNAL OF HEMATOLOGY
  • 2005-05. Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope in NATURE
  • 2004-11. Identification of human brain tumour initiating cells in NATURE
  • 2004-12. Generation of a synthetic lymphoid tissue–like organoid in mice in NATURE BIOTECHNOLOGY
  • 1990-10. The scid mutation in mice causes a general defect in DNA repair in NATURE
  • 1997-07. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell in NATURE MEDICINE
  • 2005-03. BCR-ABL-transduced human cord blood cells produce abnormal populations in immunodeficient mice in LEUKEMIA
  • 2004-02. NOD/SCID mice engineered to express human IL-3, GM-CSF and Steel factor constitutively mobilize engrafted human progenitors and compromise human stem cell regeneration in LEUKEMIA
  • 2006-03. Rapid analysis of T-cell selection in vivo using T cell–receptor retrogenic mice in NATURE METHODS
  • 2001-11. Stem cells, cancer, and cancer stem cells in NATURE
  • 2003-07. Bone marrow–derived stem cells initiate pancreatic regeneration in NATURE BIOTECHNOLOGY
  • 2003-04. Transplanted bone marrow regenerates liver by cell fusion in NATURE
  • 2003-12. Applying the principles of stem-cell biology to cancer in NATURE REVIEWS CANCER
  • 2007-01. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice in NATURE
  • 2006-11. Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1 in NATURE MEDICINE
  • Journal

    TITLE

    Nature Reviews Immunology

    ISSUE

    2

    VOLUME

    7

    Author Affiliations

    Related Patents

  • Animal Model For The Evaluation Of The Efficacy Of An Hiv Vaccine
  • Animal Model For The Evaluation Of The Efficacy Of An Hiv Vaccine
  • Animal Models And Therapeutic Molecules
  • A New Biomarker Expressed In Pancreatic Beta Cells Useful In Imaging Or Targeting Beta Cells
  • Humanized M-Csf Mice
  • Transgenic Immunodeficient Mouse Expressing Human Sirpα
  • Animal Models And Therapeutic Molecules
  • Il-15 Mediated Nk And T Cell Maturation
  • Hairless Nod Scid Mouse
  • Immunocompetent Xenograft Model
  • Animal Models And Therapeutic Molecules
  • Genetically Modified Non-Human Animals And Methods Of Use Thereof
  • Genetically Modified Major Histocompatibility Complex Animals
  • Genetically Modified Non-Human Animals And Methods Of Use Thereof
  • Animal Model For The Human Immune System, And Method For Producing The Same
  • Genetically Modified Rat Models For Severe Combined Immunodeficiency (Scid)
  • Genetically Modified Major Histocompatibility Complex Animals
  • Human Sirpα Transgenic Mice And Their Methods Of Use
  • Genetically Modified Non-Human Animals And Methods Of Use Thereof
  • Humanized T Cell Co-Receptor Mice
  • Hairless Nod Scid Mouse
  • Genetically Modified Major Histocompatibility Complex Animals
  • Transgenic Immunodeficient Mouse Expressing Human Sirp-Alpha
  • Animal Models And Therapeutic Molecules
  • Genetically Modified Major Histocompatibility Complex Animals
  • Method Of Expanding Human Hepatocytes In Vivo
  • Genetically Modified Major Histocompatibility Complex Mice
  • Human Sirpaalpha Transgenic Animals And Their Methods Of Use
  • Humanized Mice Without Conditioning.
  • Transgenic Immunodefficient Mouse Expressing Human Sirpalpha.
  • Humam Sirpaalpha Transgenic Animals And Their Methods Of Use
  • Manipulation Of Immunoglobulin Gene Diversity And Multi-Antibody Therapeutics
  • Animal Models And Therapeutic Molecules
  • Dendritic Cell-Boosted Humanized Immune System Mice
  • Genetically Modified Major Histocompatibility Complex Mice
  • Animal Model For The Human Immune System, And Method For Producing The Same
  • Mouse Model For Engraftment Potential
  • Highly Immunodeficient Mouse Optimized For Bioimaging
  • Animal Models And Therapeutic Molecules
  • Boosting Human Dendritic Cell Development, Homeostasis And Function In Xenografted Immunodeficient Mice
  • Rodent Therapeutic Model Humanized For Liver And Bone Marrow
  • Genetically Modified Mice And Engraftment
  • Genetically Modified Major Histocompatibility Complex Mice
  • Genetically Modified Mice And Engraftment
  • Humanized M-Csf Mice
  • Mouse Model For Engraftment Potential
  • Humam Sirpaalpha Transgenic Animals And Their Methods Of Use
  • A Humanized Non-Human Mammal Model Of Malaria And Uses Thereof
  • Animal Models And Therapeutic Molecules
  • New Mouse Having Mutations E.G. Mutation In Both Alleles Of Gene Encoding For Interleukin-2 Receptor-Gamma-Chain, Useful For Biomedical Research, For Vaccine Development, Antibody Development Or The Production Of Human Cells Or Tissues
  • Hairless Nod Scid Mouse
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nri2017

    DOI

    http://dx.doi.org/10.1038/nri2017

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1026380926

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/17259968


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biochemistry and Cell Biology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Chimera", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Communicable Diseases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Disease Models, Animal", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Hematopoiesis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mice", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mice, Knockout", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mice, SCID", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mice, Transgenic", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Neoplasms", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Jackson Laboratory", 
              "id": "https://www.grid.ac/institutes/grid.249880.f", 
              "name": [
                "The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA. lds@jax.org"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shultz", 
            "givenName": "Leonard D", 
            "id": "sg:person.015215456477.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015215456477.17"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Ishikawa", 
            "givenName": "Fumihiko", 
            "id": "sg:person.0662642220.52", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662642220.52"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Greiner", 
            "givenName": "Dale L", 
            "id": "sg:person.01332426414.94", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332426414.94"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1128/jvi.79.21.13797-13799.2005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000103814"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1749-6632.2001.tb03577.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001393710"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1096/fj.03-1444fje", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001505174"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.leu.2403829", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001825768", 
              "https://doi.org/10.1038/sj.leu.2403829"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.leu.2403829", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001825768", 
              "https://doi.org/10.1038/sj.leu.2403829"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1742-4690-3-76", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001889034", 
              "https://doi.org/10.1186/1742-4690-3-76"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cellimm.2005.02.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001995956"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.leu.2403985", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002153190", 
              "https://doi.org/10.1038/sj.leu.2403985"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.leu.2403985", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002153190", 
              "https://doi.org/10.1038/sj.leu.2403985"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature05372", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002972347", 
              "https://doi.org/10.1038/nature05372"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature05372", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002972347", 
              "https://doi.org/10.1038/nature05372"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ejca.2006.01.036", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003517598"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg1827", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003938339", 
              "https://doi.org/10.1038/nrg1827"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg1827", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003938339", 
              "https://doi.org/10.1038/nrg1827"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/1074-7613(95)90047-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004958298"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.177.1.191", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005347048"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-03-3764", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006433777"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/hep.21209", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006516085"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(92)90030-g", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007090770"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.smim.2005.02.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007781558"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/cimm.1996.0193", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009021073"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc1232", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009107668", 
              "https://doi.org/10.1038/nrc1232"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc1232", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009107668", 
              "https://doi.org/10.1038/nrc1232"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(92)90029-c", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009230025"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2353/ajpath.2006.060312", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009876530"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.clim.2004.04.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010135422"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.174.10.6477", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010296345"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1039", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010915317", 
              "https://doi.org/10.1038/nbt1039"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1039", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010915317", 
              "https://doi.org/10.1038/nbt1039"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-9440(10)63352-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011067624"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.coi.2006.09.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011677646"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.190.8.1059", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011827804"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0145-2126(85)90044-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011842477"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000236205", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013406625"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth858", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013508379", 
              "https://doi.org/10.1038/nmeth858"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth858", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013508379", 
              "https://doi.org/10.1038/nmeth858"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1634/stemcells.2005-0340", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014034245"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1634/stemcells.2005-0340", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014034245"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.174.4.1938", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015028558"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/jvi.78.24.13891-13900.2004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015262658"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm0696-689", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017053622", 
              "https://doi.org/10.1038/nm0696-689"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.91.19.9146", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017808655"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/347479a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017915075", 
              "https://doi.org/10.1038/347479a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0530291100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018724794"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature01539", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020262287", 
              "https://doi.org/10.1038/nature01539"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature01539", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020262287", 
              "https://doi.org/10.1038/nature01539"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.173.3.659", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020492167"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0630420100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020666983"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0604493103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020753887"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.20051547", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020761418"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/335256a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020872822", 
              "https://doi.org/10.1038/335256a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35102167", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021100179", 
              "https://doi.org/10.1038/35102167"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35102167", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021100179", 
              "https://doi.org/10.1038/35102167"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci11519", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021193950"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ijpara.2005.10.012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021637852"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm0797-730", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022333282", 
              "https://doi.org/10.1038/nm0797-730"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1462-5822.2003.00321.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022810448"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3727/000000006783982313", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024154850"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3727/000000006783982313", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024154850"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci20325", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024219345"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.0001-2815.2004.00243.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024622864"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1634/stemcells.2004-0359", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025407148"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1634/stemcells.2004-0359", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025407148"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1074-7613(02)00365-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025836630"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/500840", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026108224"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1532/ijh97.05144", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026541312", 
              "https://doi.org/10.1532/ijh97.05144"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1532/ijh97.05144", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026541312", 
              "https://doi.org/10.1532/ijh97.05144"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03128", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027226854", 
              "https://doi.org/10.1038/nature03128"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03128", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027226854", 
              "https://doi.org/10.1038/nature03128"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/301527a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028006427", 
              "https://doi.org/10.1038/301527a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1634/stemcells.21-2-217", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029749383"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2004-02-0656", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029798728"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-9440(10)64379-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031003719"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0604244103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031259370"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1634/stemcells.2005-0014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031567169"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1634/stemcells.2005-0014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031567169"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt841", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031934467", 
              "https://doi.org/10.1038/nbt841"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt841", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031934467", 
              "https://doi.org/10.1038/nbt841"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.180.5.1817", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031992877"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.transproceed.2006.01.061", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032054546"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1096/fj.05-4286lsf", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032657273"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0065-2776(08)60855-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032772863"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm1431", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033471103", 
              "https://doi.org/10.1038/nm1431"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm1431", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033471103", 
              "https://doi.org/10.1038/nm1431"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2002-07-1995", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033580593"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/eji.1830200832", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033913040"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.micinf.2005.12.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033967618"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.20041888", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034267665"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.20041888", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034267665"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1161/01.cir.0000150796.18473.8e", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034372137"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.212221199", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034505129"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.leu.2401236", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034657951", 
              "https://doi.org/10.1038/sj.leu.2401236"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.leu.2401236", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034657951", 
              "https://doi.org/10.1038/sj.leu.2401236"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci20622", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034811176"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1093933", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035570116"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2001-12-0207", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035575608"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000232530", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035882555"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1634/stemcells.2005-0079", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036104595"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1634/stemcells.2005-0079", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036104595"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/diabetes.53.4.971", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036254944"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.leu.2403650", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036382312", 
              "https://doi.org/10.1038/sj.leu.2403650"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.leu.2403650", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036382312", 
              "https://doi.org/10.1038/sj.leu.2403650"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2004-07-2561", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037363769"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03625", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038060126", 
              "https://doi.org/10.1038/nature03625"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03625", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038060126", 
              "https://doi.org/10.1038/nature03625"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.tp.0000083041.44829.2c", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038604279"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.tp.0000083041.44829.2c", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038604279"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2005-02-0516", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039444744"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.immuni.2006.10.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039682414"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.92.2.377", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039826657"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0070-2153(06)74007-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041088676"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/jvi.77.9.5286-5294.2003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041959704"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf02743266", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042345869", 
              "https://doi.org/10.1007/bf02743266"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf02743266", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042345869", 
              "https://doi.org/10.1007/bf02743266"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf02743266", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042345869", 
              "https://doi.org/10.1007/bf02743266"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2141.2006.06155.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043846009"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.169.1.204", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043865090"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2141.2005.05578.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043938837"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2141.2005.05578.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043938837"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2003-11-3961", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044185628"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/stem.5530130202", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044889857"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/stem.5530130202", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044889857"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.immunol.14.1.179", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044936733"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/diabetes.54.10.2867", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045844747"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ijc.20688", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045963893"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.leu.2403222", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046952304", 
              "https://doi.org/10.1038/sj.leu.2403222"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.leu.2403222", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046952304", 
              "https://doi.org/10.1038/sj.leu.2403222"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0301-472x(03)00193-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047077600"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0301-472x(03)00193-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047077600"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/smim.1996.0032", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047369297"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2006-04-017681", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047664517"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0510613103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048047958"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1096/fj.05-4863fje", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049284199"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/smim.1996.0030", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049320735"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/smim.1996.0029", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049361401"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.iy.09.040191.002151", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049629632"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm886", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049979157", 
              "https://doi.org/10.1038/nm886"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm886", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049979157", 
              "https://doi.org/10.1038/nm886"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1096/fj.04-2396fje", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051164954"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2005-12-017319", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051288067"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2002-10-3241", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051819848"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/stem.160166", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052062698"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/stem.160166", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052062698"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/intimm/dxh226", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052136997"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci11708", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052358776"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2006-01-0190", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053311304"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1017/s0016672300010168", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053876109"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1017/s0016672300010168", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053876109"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/scd.2004.13.677", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059309430"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/scd.2006.15.254", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059309575"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/infdis/172.4.974", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059705487"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1372131", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062478159"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.283.5402.682", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062564015"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.2971269", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062578383"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.164.5.2496", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1074591665"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.165.1.518", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1074656406"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1075173478", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1075582003", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1076588047", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.173.7.4699", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1076895621"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.176.4.2053", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077184684"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.176.5.3257", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077192137"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jnci/59.1.221", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1079653369"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082600667", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082860452", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082997625", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1083063308", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1083072502", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1083103470", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2007-02", 
        "datePublishedReg": "2007-02-01", 
        "description": "The culmination of decades of research on humanized mice is leading to advances in our understanding of human haematopoiesis, innate and adaptive immunity, autoimmunity, infectious diseases, cancer biology and regenerative medicine. In this Review, we discuss the development of these new generations of humanized mice, how they will facilitate translational research in several biomedical disciplines and approaches to overcome the remaining limitations of these models.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1038/nri2017", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1029717", 
            "issn": [
              "1474-1733", 
              "1474-1741"
            ], 
            "name": "Nature Reviews Immunology", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "2", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "7"
          }
        ], 
        "name": "Humanized mice in translational biomedical research", 
        "pagination": "118-130", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "7dad8d77dd99db90d16e483a8597226e5d7fcca8f6ee3ac953c9319e3dd22a71"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "17259968"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "101124169"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/nri2017"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1026380926"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/nri2017", 
          "https://app.dimensions.ai/details/publication/pub.1026380926"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-10T12:58", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8659_00000424.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://www.nature.com/nri/journal/v7/n2/full/nri2017.html"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nri2017'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nri2017'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nri2017'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nri2017'


     

    This table displays all metadata directly associated to this object as RDF triples.

    552 TRIPLES      21 PREDICATES      177 URIs      32 LITERALS      20 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/nri2017 schema:about N06db62f968d544cdb76e7d73af386861
    2 N09bcf944c516477a8a7e387324ddffa3
    3 N23ade32694724796902be570462660cf
    4 N57666bf8564c4f449ffd4c259a881faa
    5 N59ed9430c8e843efa8203f84f0c68661
    6 N7b85447604844f0e9940ad64bb6777cd
    7 N8a80e99e9805439c80366d7fd20264ac
    8 N8d6b7a33cdd3450391f2870fe3e4de09
    9 N9081e3baf5ae4302b4085dedaa7fa554
    10 Na52df539cfc243ba822c3dfa2814bc52
    11 Nd79729114bca40d5bb6f23f3167a85b8
    12 anzsrc-for:06
    13 anzsrc-for:0601
    14 schema:author N6dd4f1aa744143fcb084b787f77e9dd0
    15 schema:citation sg:pub.10.1007/bf02743266
    16 sg:pub.10.1038/301527a0
    17 sg:pub.10.1038/335256a0
    18 sg:pub.10.1038/347479a0
    19 sg:pub.10.1038/35102167
    20 sg:pub.10.1038/nature01539
    21 sg:pub.10.1038/nature03128
    22 sg:pub.10.1038/nature03625
    23 sg:pub.10.1038/nature05372
    24 sg:pub.10.1038/nbt1039
    25 sg:pub.10.1038/nbt841
    26 sg:pub.10.1038/nm0696-689
    27 sg:pub.10.1038/nm0797-730
    28 sg:pub.10.1038/nm1431
    29 sg:pub.10.1038/nm886
    30 sg:pub.10.1038/nmeth858
    31 sg:pub.10.1038/nrc1232
    32 sg:pub.10.1038/nrg1827
    33 sg:pub.10.1038/sj.leu.2401236
    34 sg:pub.10.1038/sj.leu.2403222
    35 sg:pub.10.1038/sj.leu.2403650
    36 sg:pub.10.1038/sj.leu.2403829
    37 sg:pub.10.1038/sj.leu.2403985
    38 sg:pub.10.1186/1742-4690-3-76
    39 sg:pub.10.1532/ijh97.05144
    40 https://app.dimensions.ai/details/publication/pub.1075173478
    41 https://app.dimensions.ai/details/publication/pub.1075582003
    42 https://app.dimensions.ai/details/publication/pub.1076588047
    43 https://app.dimensions.ai/details/publication/pub.1082600667
    44 https://app.dimensions.ai/details/publication/pub.1082860452
    45 https://app.dimensions.ai/details/publication/pub.1082997625
    46 https://app.dimensions.ai/details/publication/pub.1083063308
    47 https://app.dimensions.ai/details/publication/pub.1083072502
    48 https://app.dimensions.ai/details/publication/pub.1083103470
    49 https://doi.org/10.1002/eji.1830200832
    50 https://doi.org/10.1002/hep.21209
    51 https://doi.org/10.1002/ijc.20688
    52 https://doi.org/10.1002/stem.160166
    53 https://doi.org/10.1002/stem.5530130202
    54 https://doi.org/10.1006/cimm.1996.0193
    55 https://doi.org/10.1006/smim.1996.0029
    56 https://doi.org/10.1006/smim.1996.0030
    57 https://doi.org/10.1006/smim.1996.0032
    58 https://doi.org/10.1016/0092-8674(92)90029-c
    59 https://doi.org/10.1016/0092-8674(92)90030-g
    60 https://doi.org/10.1016/0145-2126(85)90044-x
    61 https://doi.org/10.1016/1074-7613(95)90047-0
    62 https://doi.org/10.1016/j.cellimm.2005.02.003
    63 https://doi.org/10.1016/j.clim.2004.04.006
    64 https://doi.org/10.1016/j.coi.2006.09.003
    65 https://doi.org/10.1016/j.ejca.2006.01.036
    66 https://doi.org/10.1016/j.ijpara.2005.10.012
    67 https://doi.org/10.1016/j.immuni.2006.10.011
    68 https://doi.org/10.1016/j.micinf.2005.12.004
    69 https://doi.org/10.1016/j.smim.2005.02.006
    70 https://doi.org/10.1016/j.transproceed.2006.01.061
    71 https://doi.org/10.1016/s0002-9440(10)63352-4
    72 https://doi.org/10.1016/s0002-9440(10)64379-9
    73 https://doi.org/10.1016/s0065-2776(08)60855-x
    74 https://doi.org/10.1016/s0070-2153(06)74007-8
    75 https://doi.org/10.1016/s0301-472x(03)00193-0
    76 https://doi.org/10.1016/s1074-7613(02)00365-5
    77 https://doi.org/10.1017/s0016672300010168
    78 https://doi.org/10.1046/j.1462-5822.2003.00321.x
    79 https://doi.org/10.1073/pnas.0510613103
    80 https://doi.org/10.1073/pnas.0530291100
    81 https://doi.org/10.1073/pnas.0604244103
    82 https://doi.org/10.1073/pnas.0604493103
    83 https://doi.org/10.1073/pnas.0630420100
    84 https://doi.org/10.1073/pnas.212221199
    85 https://doi.org/10.1073/pnas.91.19.9146
    86 https://doi.org/10.1073/pnas.92.2.377
    87 https://doi.org/10.1084/jem.173.3.659
    88 https://doi.org/10.1084/jem.177.1.191
    89 https://doi.org/10.1084/jem.180.5.1817
    90 https://doi.org/10.1084/jem.190.8.1059
    91 https://doi.org/10.1084/jem.20041888
    92 https://doi.org/10.1084/jem.20051547
    93 https://doi.org/10.1086/500840
    94 https://doi.org/10.1089/scd.2004.13.677
    95 https://doi.org/10.1089/scd.2006.15.254
    96 https://doi.org/10.1093/infdis/172.4.974
    97 https://doi.org/10.1093/intimm/dxh226
    98 https://doi.org/10.1093/jnci/59.1.221
    99 https://doi.org/10.1096/fj.03-1444fje
    100 https://doi.org/10.1096/fj.04-2396fje
    101 https://doi.org/10.1096/fj.05-4286lsf
    102 https://doi.org/10.1096/fj.05-4863fje
    103 https://doi.org/10.1097/01.tp.0000083041.44829.2c
    104 https://doi.org/10.1111/j.0001-2815.2004.00243.x
    105 https://doi.org/10.1111/j.1365-2141.2005.05578.x
    106 https://doi.org/10.1111/j.1365-2141.2006.06155.x
    107 https://doi.org/10.1111/j.1749-6632.2001.tb03577.x
    108 https://doi.org/10.1126/science.1093933
    109 https://doi.org/10.1126/science.1372131
    110 https://doi.org/10.1126/science.283.5402.682
    111 https://doi.org/10.1126/science.2971269
    112 https://doi.org/10.1128/jvi.77.9.5286-5294.2003
    113 https://doi.org/10.1128/jvi.78.24.13891-13900.2004
    114 https://doi.org/10.1128/jvi.79.21.13797-13799.2005
    115 https://doi.org/10.1146/annurev.immunol.14.1.179
    116 https://doi.org/10.1146/annurev.iy.09.040191.002151
    117 https://doi.org/10.1158/0008-5472.can-03-3764
    118 https://doi.org/10.1159/000232530
    119 https://doi.org/10.1159/000236205
    120 https://doi.org/10.1161/01.cir.0000150796.18473.8e
    121 https://doi.org/10.1172/jci11519
    122 https://doi.org/10.1172/jci11708
    123 https://doi.org/10.1172/jci20325
    124 https://doi.org/10.1172/jci20622
    125 https://doi.org/10.1182/blood-2001-12-0207
    126 https://doi.org/10.1182/blood-2002-07-1995
    127 https://doi.org/10.1182/blood-2002-10-3241
    128 https://doi.org/10.1182/blood-2003-11-3961
    129 https://doi.org/10.1182/blood-2004-02-0656
    130 https://doi.org/10.1182/blood-2004-07-2561
    131 https://doi.org/10.1182/blood-2005-02-0516
    132 https://doi.org/10.1182/blood-2005-12-017319
    133 https://doi.org/10.1182/blood-2006-01-0190
    134 https://doi.org/10.1182/blood-2006-04-017681
    135 https://doi.org/10.1634/stemcells.2004-0359
    136 https://doi.org/10.1634/stemcells.2005-0014
    137 https://doi.org/10.1634/stemcells.2005-0079
    138 https://doi.org/10.1634/stemcells.2005-0340
    139 https://doi.org/10.1634/stemcells.21-2-217
    140 https://doi.org/10.2337/diabetes.53.4.971
    141 https://doi.org/10.2337/diabetes.54.10.2867
    142 https://doi.org/10.2353/ajpath.2006.060312
    143 https://doi.org/10.3727/000000006783982313
    144 https://doi.org/10.4049/jimmunol.164.5.2496
    145 https://doi.org/10.4049/jimmunol.165.1.518
    146 https://doi.org/10.4049/jimmunol.169.1.204
    147 https://doi.org/10.4049/jimmunol.173.7.4699
    148 https://doi.org/10.4049/jimmunol.174.10.6477
    149 https://doi.org/10.4049/jimmunol.174.4.1938
    150 https://doi.org/10.4049/jimmunol.176.4.2053
    151 https://doi.org/10.4049/jimmunol.176.5.3257
    152 schema:datePublished 2007-02
    153 schema:datePublishedReg 2007-02-01
    154 schema:description The culmination of decades of research on humanized mice is leading to advances in our understanding of human haematopoiesis, innate and adaptive immunity, autoimmunity, infectious diseases, cancer biology and regenerative medicine. In this Review, we discuss the development of these new generations of humanized mice, how they will facilitate translational research in several biomedical disciplines and approaches to overcome the remaining limitations of these models.
    155 schema:genre research_article
    156 schema:inLanguage en
    157 schema:isAccessibleForFree false
    158 schema:isPartOf N98f22bf7acd44df99c0d0353a35e32df
    159 Nc09f618814c74a2482e5830d35c01dbb
    160 sg:journal.1029717
    161 schema:name Humanized mice in translational biomedical research
    162 schema:pagination 118-130
    163 schema:productId N9ae48bf19a6542d59777462b76cbfe4d
    164 Nac4f91565f874b3ea2188cf3f6734c28
    165 Nc32eb2c915844364b1f05c3f89abcc9e
    166 Nd9fc37a295e94bf09fb05995594fb25c
    167 Ne8ec9bd867844479b6dab7bc8ebd606b
    168 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026380926
    169 https://doi.org/10.1038/nri2017
    170 schema:sdDatePublished 2019-04-10T12:58
    171 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    172 schema:sdPublisher Nc9c8dd9c9c3f4c1aaee85e5613e6d200
    173 schema:url http://www.nature.com/nri/journal/v7/n2/full/nri2017.html
    174 sgo:license sg:explorer/license/
    175 sgo:sdDataset articles
    176 rdf:type schema:ScholarlyArticle
    177 N06db62f968d544cdb76e7d73af386861 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    178 schema:name Communicable Diseases
    179 rdf:type schema:DefinedTerm
    180 N09bcf944c516477a8a7e387324ddffa3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    181 schema:name Hematopoiesis
    182 rdf:type schema:DefinedTerm
    183 N23ade32694724796902be570462660cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    184 schema:name Humans
    185 rdf:type schema:DefinedTerm
    186 N57666bf8564c4f449ffd4c259a881faa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    187 schema:name Mice, Transgenic
    188 rdf:type schema:DefinedTerm
    189 N59ed9430c8e843efa8203f84f0c68661 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    190 schema:name Chimera
    191 rdf:type schema:DefinedTerm
    192 N6dd4f1aa744143fcb084b787f77e9dd0 rdf:first sg:person.015215456477.17
    193 rdf:rest N9e47e8dd0beb4ed486b3d2fdb8666353
    194 N7b85447604844f0e9940ad64bb6777cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    195 schema:name Mice, SCID
    196 rdf:type schema:DefinedTerm
    197 N8a80e99e9805439c80366d7fd20264ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    198 schema:name Neoplasms
    199 rdf:type schema:DefinedTerm
    200 N8d6b7a33cdd3450391f2870fe3e4de09 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    201 schema:name Disease Models, Animal
    202 rdf:type schema:DefinedTerm
    203 N9081e3baf5ae4302b4085dedaa7fa554 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    204 schema:name Mice, Knockout
    205 rdf:type schema:DefinedTerm
    206 N98f22bf7acd44df99c0d0353a35e32df schema:volumeNumber 7
    207 rdf:type schema:PublicationVolume
    208 N9ae48bf19a6542d59777462b76cbfe4d schema:name readcube_id
    209 schema:value 7dad8d77dd99db90d16e483a8597226e5d7fcca8f6ee3ac953c9319e3dd22a71
    210 rdf:type schema:PropertyValue
    211 N9e47e8dd0beb4ed486b3d2fdb8666353 rdf:first sg:person.0662642220.52
    212 rdf:rest Nd2694c31f81f4b1ea635e0dd7859d9bb
    213 Na52df539cfc243ba822c3dfa2814bc52 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    214 schema:name Animals
    215 rdf:type schema:DefinedTerm
    216 Nac4f91565f874b3ea2188cf3f6734c28 schema:name pubmed_id
    217 schema:value 17259968
    218 rdf:type schema:PropertyValue
    219 Nc09f618814c74a2482e5830d35c01dbb schema:issueNumber 2
    220 rdf:type schema:PublicationIssue
    221 Nc32eb2c915844364b1f05c3f89abcc9e schema:name doi
    222 schema:value 10.1038/nri2017
    223 rdf:type schema:PropertyValue
    224 Nc9c8dd9c9c3f4c1aaee85e5613e6d200 schema:name Springer Nature - SN SciGraph project
    225 rdf:type schema:Organization
    226 Nd2694c31f81f4b1ea635e0dd7859d9bb rdf:first sg:person.01332426414.94
    227 rdf:rest rdf:nil
    228 Nd79729114bca40d5bb6f23f3167a85b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    229 schema:name Mice
    230 rdf:type schema:DefinedTerm
    231 Nd9fc37a295e94bf09fb05995594fb25c schema:name dimensions_id
    232 schema:value pub.1026380926
    233 rdf:type schema:PropertyValue
    234 Ne8ec9bd867844479b6dab7bc8ebd606b schema:name nlm_unique_id
    235 schema:value 101124169
    236 rdf:type schema:PropertyValue
    237 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    238 schema:name Biological Sciences
    239 rdf:type schema:DefinedTerm
    240 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    241 schema:name Biochemistry and Cell Biology
    242 rdf:type schema:DefinedTerm
    243 sg:journal.1029717 schema:issn 1474-1733
    244 1474-1741
    245 schema:name Nature Reviews Immunology
    246 rdf:type schema:Periodical
    247 sg:person.01332426414.94 schema:familyName Greiner
    248 schema:givenName Dale L
    249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332426414.94
    250 rdf:type schema:Person
    251 sg:person.015215456477.17 schema:affiliation https://www.grid.ac/institutes/grid.249880.f
    252 schema:familyName Shultz
    253 schema:givenName Leonard D
    254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015215456477.17
    255 rdf:type schema:Person
    256 sg:person.0662642220.52 schema:familyName Ishikawa
    257 schema:givenName Fumihiko
    258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662642220.52
    259 rdf:type schema:Person
    260 sg:pub.10.1007/bf02743266 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042345869
    261 https://doi.org/10.1007/bf02743266
    262 rdf:type schema:CreativeWork
    263 sg:pub.10.1038/301527a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028006427
    264 https://doi.org/10.1038/301527a0
    265 rdf:type schema:CreativeWork
    266 sg:pub.10.1038/335256a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020872822
    267 https://doi.org/10.1038/335256a0
    268 rdf:type schema:CreativeWork
    269 sg:pub.10.1038/347479a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017915075
    270 https://doi.org/10.1038/347479a0
    271 rdf:type schema:CreativeWork
    272 sg:pub.10.1038/35102167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021100179
    273 https://doi.org/10.1038/35102167
    274 rdf:type schema:CreativeWork
    275 sg:pub.10.1038/nature01539 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020262287
    276 https://doi.org/10.1038/nature01539
    277 rdf:type schema:CreativeWork
    278 sg:pub.10.1038/nature03128 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027226854
    279 https://doi.org/10.1038/nature03128
    280 rdf:type schema:CreativeWork
    281 sg:pub.10.1038/nature03625 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038060126
    282 https://doi.org/10.1038/nature03625
    283 rdf:type schema:CreativeWork
    284 sg:pub.10.1038/nature05372 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002972347
    285 https://doi.org/10.1038/nature05372
    286 rdf:type schema:CreativeWork
    287 sg:pub.10.1038/nbt1039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010915317
    288 https://doi.org/10.1038/nbt1039
    289 rdf:type schema:CreativeWork
    290 sg:pub.10.1038/nbt841 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031934467
    291 https://doi.org/10.1038/nbt841
    292 rdf:type schema:CreativeWork
    293 sg:pub.10.1038/nm0696-689 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017053622
    294 https://doi.org/10.1038/nm0696-689
    295 rdf:type schema:CreativeWork
    296 sg:pub.10.1038/nm0797-730 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022333282
    297 https://doi.org/10.1038/nm0797-730
    298 rdf:type schema:CreativeWork
    299 sg:pub.10.1038/nm1431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033471103
    300 https://doi.org/10.1038/nm1431
    301 rdf:type schema:CreativeWork
    302 sg:pub.10.1038/nm886 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049979157
    303 https://doi.org/10.1038/nm886
    304 rdf:type schema:CreativeWork
    305 sg:pub.10.1038/nmeth858 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013508379
    306 https://doi.org/10.1038/nmeth858
    307 rdf:type schema:CreativeWork
    308 sg:pub.10.1038/nrc1232 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009107668
    309 https://doi.org/10.1038/nrc1232
    310 rdf:type schema:CreativeWork
    311 sg:pub.10.1038/nrg1827 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003938339
    312 https://doi.org/10.1038/nrg1827
    313 rdf:type schema:CreativeWork
    314 sg:pub.10.1038/sj.leu.2401236 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034657951
    315 https://doi.org/10.1038/sj.leu.2401236
    316 rdf:type schema:CreativeWork
    317 sg:pub.10.1038/sj.leu.2403222 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046952304
    318 https://doi.org/10.1038/sj.leu.2403222
    319 rdf:type schema:CreativeWork
    320 sg:pub.10.1038/sj.leu.2403650 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036382312
    321 https://doi.org/10.1038/sj.leu.2403650
    322 rdf:type schema:CreativeWork
    323 sg:pub.10.1038/sj.leu.2403829 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001825768
    324 https://doi.org/10.1038/sj.leu.2403829
    325 rdf:type schema:CreativeWork
    326 sg:pub.10.1038/sj.leu.2403985 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002153190
    327 https://doi.org/10.1038/sj.leu.2403985
    328 rdf:type schema:CreativeWork
    329 sg:pub.10.1186/1742-4690-3-76 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001889034
    330 https://doi.org/10.1186/1742-4690-3-76
    331 rdf:type schema:CreativeWork
    332 sg:pub.10.1532/ijh97.05144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026541312
    333 https://doi.org/10.1532/ijh97.05144
    334 rdf:type schema:CreativeWork
    335 https://app.dimensions.ai/details/publication/pub.1075173478 schema:CreativeWork
    336 https://app.dimensions.ai/details/publication/pub.1075582003 schema:CreativeWork
    337 https://app.dimensions.ai/details/publication/pub.1076588047 schema:CreativeWork
    338 https://app.dimensions.ai/details/publication/pub.1082600667 schema:CreativeWork
    339 https://app.dimensions.ai/details/publication/pub.1082860452 schema:CreativeWork
    340 https://app.dimensions.ai/details/publication/pub.1082997625 schema:CreativeWork
    341 https://app.dimensions.ai/details/publication/pub.1083063308 schema:CreativeWork
    342 https://app.dimensions.ai/details/publication/pub.1083072502 schema:CreativeWork
    343 https://app.dimensions.ai/details/publication/pub.1083103470 schema:CreativeWork
    344 https://doi.org/10.1002/eji.1830200832 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033913040
    345 rdf:type schema:CreativeWork
    346 https://doi.org/10.1002/hep.21209 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006516085
    347 rdf:type schema:CreativeWork
    348 https://doi.org/10.1002/ijc.20688 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045963893
    349 rdf:type schema:CreativeWork
    350 https://doi.org/10.1002/stem.160166 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052062698
    351 rdf:type schema:CreativeWork
    352 https://doi.org/10.1002/stem.5530130202 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044889857
    353 rdf:type schema:CreativeWork
    354 https://doi.org/10.1006/cimm.1996.0193 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009021073
    355 rdf:type schema:CreativeWork
    356 https://doi.org/10.1006/smim.1996.0029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049361401
    357 rdf:type schema:CreativeWork
    358 https://doi.org/10.1006/smim.1996.0030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049320735
    359 rdf:type schema:CreativeWork
    360 https://doi.org/10.1006/smim.1996.0032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047369297
    361 rdf:type schema:CreativeWork
    362 https://doi.org/10.1016/0092-8674(92)90029-c schema:sameAs https://app.dimensions.ai/details/publication/pub.1009230025
    363 rdf:type schema:CreativeWork
    364 https://doi.org/10.1016/0092-8674(92)90030-g schema:sameAs https://app.dimensions.ai/details/publication/pub.1007090770
    365 rdf:type schema:CreativeWork
    366 https://doi.org/10.1016/0145-2126(85)90044-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1011842477
    367 rdf:type schema:CreativeWork
    368 https://doi.org/10.1016/1074-7613(95)90047-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004958298
    369 rdf:type schema:CreativeWork
    370 https://doi.org/10.1016/j.cellimm.2005.02.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001995956
    371 rdf:type schema:CreativeWork
    372 https://doi.org/10.1016/j.clim.2004.04.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010135422
    373 rdf:type schema:CreativeWork
    374 https://doi.org/10.1016/j.coi.2006.09.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011677646
    375 rdf:type schema:CreativeWork
    376 https://doi.org/10.1016/j.ejca.2006.01.036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003517598
    377 rdf:type schema:CreativeWork
    378 https://doi.org/10.1016/j.ijpara.2005.10.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021637852
    379 rdf:type schema:CreativeWork
    380 https://doi.org/10.1016/j.immuni.2006.10.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039682414
    381 rdf:type schema:CreativeWork
    382 https://doi.org/10.1016/j.micinf.2005.12.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033967618
    383 rdf:type schema:CreativeWork
    384 https://doi.org/10.1016/j.smim.2005.02.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007781558
    385 rdf:type schema:CreativeWork
    386 https://doi.org/10.1016/j.transproceed.2006.01.061 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032054546
    387 rdf:type schema:CreativeWork
    388 https://doi.org/10.1016/s0002-9440(10)63352-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011067624
    389 rdf:type schema:CreativeWork
    390 https://doi.org/10.1016/s0002-9440(10)64379-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031003719
    391 rdf:type schema:CreativeWork
    392 https://doi.org/10.1016/s0065-2776(08)60855-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032772863
    393 rdf:type schema:CreativeWork
    394 https://doi.org/10.1016/s0070-2153(06)74007-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041088676
    395 rdf:type schema:CreativeWork
    396 https://doi.org/10.1016/s0301-472x(03)00193-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047077600
    397 rdf:type schema:CreativeWork
    398 https://doi.org/10.1016/s1074-7613(02)00365-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025836630
    399 rdf:type schema:CreativeWork
    400 https://doi.org/10.1017/s0016672300010168 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053876109
    401 rdf:type schema:CreativeWork
    402 https://doi.org/10.1046/j.1462-5822.2003.00321.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1022810448
    403 rdf:type schema:CreativeWork
    404 https://doi.org/10.1073/pnas.0510613103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048047958
    405 rdf:type schema:CreativeWork
    406 https://doi.org/10.1073/pnas.0530291100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018724794
    407 rdf:type schema:CreativeWork
    408 https://doi.org/10.1073/pnas.0604244103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031259370
    409 rdf:type schema:CreativeWork
    410 https://doi.org/10.1073/pnas.0604493103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020753887
    411 rdf:type schema:CreativeWork
    412 https://doi.org/10.1073/pnas.0630420100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020666983
    413 rdf:type schema:CreativeWork
    414 https://doi.org/10.1073/pnas.212221199 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034505129
    415 rdf:type schema:CreativeWork
    416 https://doi.org/10.1073/pnas.91.19.9146 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017808655
    417 rdf:type schema:CreativeWork
    418 https://doi.org/10.1073/pnas.92.2.377 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039826657
    419 rdf:type schema:CreativeWork
    420 https://doi.org/10.1084/jem.173.3.659 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020492167
    421 rdf:type schema:CreativeWork
    422 https://doi.org/10.1084/jem.177.1.191 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005347048
    423 rdf:type schema:CreativeWork
    424 https://doi.org/10.1084/jem.180.5.1817 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031992877
    425 rdf:type schema:CreativeWork
    426 https://doi.org/10.1084/jem.190.8.1059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011827804
    427 rdf:type schema:CreativeWork
    428 https://doi.org/10.1084/jem.20041888 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034267665
    429 rdf:type schema:CreativeWork
    430 https://doi.org/10.1084/jem.20051547 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020761418
    431 rdf:type schema:CreativeWork
    432 https://doi.org/10.1086/500840 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026108224
    433 rdf:type schema:CreativeWork
    434 https://doi.org/10.1089/scd.2004.13.677 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059309430
    435 rdf:type schema:CreativeWork
    436 https://doi.org/10.1089/scd.2006.15.254 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059309575
    437 rdf:type schema:CreativeWork
    438 https://doi.org/10.1093/infdis/172.4.974 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059705487
    439 rdf:type schema:CreativeWork
    440 https://doi.org/10.1093/intimm/dxh226 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052136997
    441 rdf:type schema:CreativeWork
    442 https://doi.org/10.1093/jnci/59.1.221 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079653369
    443 rdf:type schema:CreativeWork
    444 https://doi.org/10.1096/fj.03-1444fje schema:sameAs https://app.dimensions.ai/details/publication/pub.1001505174
    445 rdf:type schema:CreativeWork
    446 https://doi.org/10.1096/fj.04-2396fje schema:sameAs https://app.dimensions.ai/details/publication/pub.1051164954
    447 rdf:type schema:CreativeWork
    448 https://doi.org/10.1096/fj.05-4286lsf schema:sameAs https://app.dimensions.ai/details/publication/pub.1032657273
    449 rdf:type schema:CreativeWork
    450 https://doi.org/10.1096/fj.05-4863fje schema:sameAs https://app.dimensions.ai/details/publication/pub.1049284199
    451 rdf:type schema:CreativeWork
    452 https://doi.org/10.1097/01.tp.0000083041.44829.2c schema:sameAs https://app.dimensions.ai/details/publication/pub.1038604279
    453 rdf:type schema:CreativeWork
    454 https://doi.org/10.1111/j.0001-2815.2004.00243.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024622864
    455 rdf:type schema:CreativeWork
    456 https://doi.org/10.1111/j.1365-2141.2005.05578.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1043938837
    457 rdf:type schema:CreativeWork
    458 https://doi.org/10.1111/j.1365-2141.2006.06155.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1043846009
    459 rdf:type schema:CreativeWork
    460 https://doi.org/10.1111/j.1749-6632.2001.tb03577.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001393710
    461 rdf:type schema:CreativeWork
    462 https://doi.org/10.1126/science.1093933 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035570116
    463 rdf:type schema:CreativeWork
    464 https://doi.org/10.1126/science.1372131 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062478159
    465 rdf:type schema:CreativeWork
    466 https://doi.org/10.1126/science.283.5402.682 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062564015
    467 rdf:type schema:CreativeWork
    468 https://doi.org/10.1126/science.2971269 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062578383
    469 rdf:type schema:CreativeWork
    470 https://doi.org/10.1128/jvi.77.9.5286-5294.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041959704
    471 rdf:type schema:CreativeWork
    472 https://doi.org/10.1128/jvi.78.24.13891-13900.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015262658
    473 rdf:type schema:CreativeWork
    474 https://doi.org/10.1128/jvi.79.21.13797-13799.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000103814
    475 rdf:type schema:CreativeWork
    476 https://doi.org/10.1146/annurev.immunol.14.1.179 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044936733
    477 rdf:type schema:CreativeWork
    478 https://doi.org/10.1146/annurev.iy.09.040191.002151 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049629632
    479 rdf:type schema:CreativeWork
    480 https://doi.org/10.1158/0008-5472.can-03-3764 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006433777
    481 rdf:type schema:CreativeWork
    482 https://doi.org/10.1159/000232530 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035882555
    483 rdf:type schema:CreativeWork
    484 https://doi.org/10.1159/000236205 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013406625
    485 rdf:type schema:CreativeWork
    486 https://doi.org/10.1161/01.cir.0000150796.18473.8e schema:sameAs https://app.dimensions.ai/details/publication/pub.1034372137
    487 rdf:type schema:CreativeWork
    488 https://doi.org/10.1172/jci11519 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021193950
    489 rdf:type schema:CreativeWork
    490 https://doi.org/10.1172/jci11708 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052358776
    491 rdf:type schema:CreativeWork
    492 https://doi.org/10.1172/jci20325 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024219345
    493 rdf:type schema:CreativeWork
    494 https://doi.org/10.1172/jci20622 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034811176
    495 rdf:type schema:CreativeWork
    496 https://doi.org/10.1182/blood-2001-12-0207 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035575608
    497 rdf:type schema:CreativeWork
    498 https://doi.org/10.1182/blood-2002-07-1995 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033580593
    499 rdf:type schema:CreativeWork
    500 https://doi.org/10.1182/blood-2002-10-3241 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051819848
    501 rdf:type schema:CreativeWork
    502 https://doi.org/10.1182/blood-2003-11-3961 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044185628
    503 rdf:type schema:CreativeWork
    504 https://doi.org/10.1182/blood-2004-02-0656 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029798728
    505 rdf:type schema:CreativeWork
    506 https://doi.org/10.1182/blood-2004-07-2561 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037363769
    507 rdf:type schema:CreativeWork
    508 https://doi.org/10.1182/blood-2005-02-0516 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039444744
    509 rdf:type schema:CreativeWork
    510 https://doi.org/10.1182/blood-2005-12-017319 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051288067
    511 rdf:type schema:CreativeWork
    512 https://doi.org/10.1182/blood-2006-01-0190 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053311304
    513 rdf:type schema:CreativeWork
    514 https://doi.org/10.1182/blood-2006-04-017681 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047664517
    515 rdf:type schema:CreativeWork
    516 https://doi.org/10.1634/stemcells.2004-0359 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025407148
    517 rdf:type schema:CreativeWork
    518 https://doi.org/10.1634/stemcells.2005-0014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031567169
    519 rdf:type schema:CreativeWork
    520 https://doi.org/10.1634/stemcells.2005-0079 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036104595
    521 rdf:type schema:CreativeWork
    522 https://doi.org/10.1634/stemcells.2005-0340 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014034245
    523 rdf:type schema:CreativeWork
    524 https://doi.org/10.1634/stemcells.21-2-217 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029749383
    525 rdf:type schema:CreativeWork
    526 https://doi.org/10.2337/diabetes.53.4.971 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036254944
    527 rdf:type schema:CreativeWork
    528 https://doi.org/10.2337/diabetes.54.10.2867 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045844747
    529 rdf:type schema:CreativeWork
    530 https://doi.org/10.2353/ajpath.2006.060312 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009876530
    531 rdf:type schema:CreativeWork
    532 https://doi.org/10.3727/000000006783982313 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024154850
    533 rdf:type schema:CreativeWork
    534 https://doi.org/10.4049/jimmunol.164.5.2496 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074591665
    535 rdf:type schema:CreativeWork
    536 https://doi.org/10.4049/jimmunol.165.1.518 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074656406
    537 rdf:type schema:CreativeWork
    538 https://doi.org/10.4049/jimmunol.169.1.204 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043865090
    539 rdf:type schema:CreativeWork
    540 https://doi.org/10.4049/jimmunol.173.7.4699 schema:sameAs https://app.dimensions.ai/details/publication/pub.1076895621
    541 rdf:type schema:CreativeWork
    542 https://doi.org/10.4049/jimmunol.174.10.6477 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010296345
    543 rdf:type schema:CreativeWork
    544 https://doi.org/10.4049/jimmunol.174.4.1938 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015028558
    545 rdf:type schema:CreativeWork
    546 https://doi.org/10.4049/jimmunol.176.4.2053 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077184684
    547 rdf:type schema:CreativeWork
    548 https://doi.org/10.4049/jimmunol.176.5.3257 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077192137
    549 rdf:type schema:CreativeWork
    550 https://www.grid.ac/institutes/grid.249880.f schema:alternateName Jackson Laboratory
    551 schema:name The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA. lds@jax.org
    552 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...