Progress and obstacles in the development of an AIDS vaccine View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2006-12

AUTHORS

Norman L Letvin

ABSTRACT

Recent experimental observations suggest approaches to immunization that might finally result in at least a partially effective vaccine against infection with HIV-1. In particular, advances in our understanding of the contribution of vaccine-elicited cellular immunity to protecting memory CD4(+) T cells from virus-mediated destruction provide rational strategies for the development of this vaccine. This is therefore an ideal time to review our current understanding of HIV-1 and its control by the immune system, as well as the remaining problems that must be solved to facilitate the development of an effective vaccine against AIDS. More... »

PAGES

930-939

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nri1959

DOI

http://dx.doi.org/10.1038/nri1959

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013015745

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17124514


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