Regulatory T cells, tumour immunity and immunotherapy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2006-04

AUTHORS

Weiping Zou

ABSTRACT

Tumours express a range of antigens, including self-antigens. Regulatory T cells are crucial for maintaining T-cell tolerance to self-antigens. Regulatory T cells are thought to dampen T-cell immunity to tumour-associated antigens and to be the main obstacle tempering successful immunotherapy and active vaccination. In this Review, I consider the nature and characteristics of regulatory T cells in the tumour microenvironment and their potential multiple suppressive mechanisms. Strategies for therapeutic targeting of regulatory T cells and the effect of regulatory T cells on current immunotherapeutic and vaccine regimens are discussed. More... »

PAGES

295-307

References to SciGraph publications

  • 2004-09. Tolerance, not immunity, crucially depends on IL-2 in NATURE REVIEWS IMMUNOLOGY
  • 2003-03. Regulatory lymphocytes: Antigen-induced regulatory T cells in autoimmunity in NATURE REVIEWS IMMUNOLOGY
  • 2002-11. Natural selection of tumor variants in the generation of “tumor escape” phenotypes in NATURE IMMUNOLOGY
  • 2004-12. Mechanisms and functional significance of tumour-induced dendritic-cell defects in NATURE REVIEWS IMMUNOLOGY
  • 2005-04. Immunosuppressive networks in the tumour environment and their therapeutic relevance in NATURE REVIEWS CANCER
  • 2002-02. Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance in NATURE IMMUNOLOGY
  • 2001-12. Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells in NATURE MEDICINE
  • 2004-09. Fatal attraction: tumors beckon regulatory T cells in NATURE MEDICINE
  • 1997-10. A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis in NATURE
  • 2003-08. Cancer vaccines: between the idea and the reality in NATURE REVIEWS IMMUNOLOGY
  • 2003-04. An essential role for Scurfin in CD4+CD25+ T regulatory cells in NATURE IMMUNOLOGY
  • 2005-04. Mechanisms of suppression by suppressor T cells in NATURE IMMUNOLOGY
  • 2003-04. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells in NATURE IMMUNOLOGY
  • 2002-06. CD4+CD25+ suppressor T cells: more questions than answers in NATURE REVIEWS IMMUNOLOGY
  • 2003-12. Modulation of tryptophan catabolism by regulatory T cells in NATURE IMMUNOLOGY
  • 2005-04. Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma in NATURE REVIEWS IMMUNOLOGY
  • 2002-08. Origin of regulatory T cells with known specificity for antigen in NATURE IMMUNOLOGY
  • 2006-09. Regulatory T cells in SEMINARS IN IMMUNOPATHOLOGY
  • 2004-10. Ido expression by dendritic cells: tolerance and tryptophan catabolism in NATURE REVIEWS IMMUNOLOGY
  • 2002-03. Tolerization of dendritic cells by TS cells: the crucial role of inhibitory receptors ILT3 and ILT4 in NATURE IMMUNOLOGY
  • 2005-04. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self in NATURE IMMUNOLOGY
  • 2005-11. Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells in NATURE MEDICINE
  • 2004-09. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival in NATURE MEDICINE
  • Journal

    TITLE

    Nature Reviews Immunology

    ISSUE

    4

    VOLUME

    6

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nri1806

    DOI

    http://dx.doi.org/10.1038/nri1806

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1004289511

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/16557261


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