2005-01
AUTHORSFrancisco González-Scarano, Julio Martín-García
ABSTRACTHIV-associated dementia (HAD) is an important complication of the central nervous system in patients who are infected with HIV-1. Although the incidence of HAD has markedly decreased since it has become possible to effectively control viral replication in the blood by administering highly active antiretroviral therapy, a less severe form of HAD, comprising a milder cognitive and motor disorder, is now potentially a serious problem. Brain macrophages and microglia are the key cell types that are infected by HIV-1 in the central nervous system, and they are likely to mediate the neurodegeneration seen in patients with HAD; however, the precise pathogenesis of this neurodegeneration is still unclear. Here, we discuss the studies that are being carried out to determine the respective contributions of infection, and monocyte and macrophage activation, to disease progression. More... »
PAGES69-81
http://scigraph.springernature.com/pub.10.1038/nri1527
DOIhttp://dx.doi.org/10.1038/nri1527
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1001952502
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/15630430
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Neurosciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "AIDS Dementia Complex",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Acquired Immunodeficiency Syndrome",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Brain",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Chemokines",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Disease Progression",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "HIV-1",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Macrophage Activation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Macrophages",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Microglia",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Neurodegenerative Diseases",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Receptors, Chemokine",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Hospital of the University of Pennsylvania",
"id": "https://www.grid.ac/institutes/grid.411115.1",
"name": [
"Department of Neurology, 3 West Gates, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, Philadelphia 19104-4283, USA. scarano@mail.med.upenn.edu"
],
"type": "Organization"
},
"familyName": "Gonz\u00e1lez-Scarano",
"givenName": "Francisco",
"id": "sg:person.0102251521.31",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0102251521.31"
],
"type": "Person"
},
{
"familyName": "Mart\u00edn-Garc\u00eda",
"givenName": "Julio",
"id": "sg:person.01074736754.53",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074736754.53"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1073/pnas.95.18.10896",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000343474"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1074/jbc.m205289200",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000371755"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ana.1011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000736542"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0306-4522(96)00373-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000861059"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/(sici)1097-4547(19970901)49:5<600::aid-jnr10>3.0.co;2-z",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001817393"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/glia.1107",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001987351"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0306-4522(00)00024-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002670255"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.94.26.14742",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003125021"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1074/jbc.274.13.8531",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005400885"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1172/jci116518",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005455747"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ana.410370315",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006147509"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/89490",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006514698",
"https://doi.org/10.1038/89490"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/89490",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006514698",
"https://doi.org/10.1038/89490"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jvi.75.8.3568-3580.2001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006704406"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.96.14.8212",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006761175"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/viro.2002.1395",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006884039"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ana.410320509",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007646414"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1365-2990.1995.tb01053.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007780500"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00005072-199911000-00005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007902932"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ana.410290106",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009014620"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002030-199714000-00006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009813643"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002030-199714000-00006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009813643"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1471-4159.1999.0732348.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010195579"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jneuroim.2003.10.049",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010280227"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/1531-8249(199909)46:3<391::aid-ana15>3.0.co;2-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011117469"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1750-3639.2002.tb00461.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011133454"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.neures.2004.01.010",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011271102"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/glia.440070106",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011477326"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0165-5728(00)00371-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011769966"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jvi.78.13.6915-6926.2004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011863018"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1084/jem.181.2.735",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013062265"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1084/jem.173.4.981",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013229225"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1146/annurev.neuro.25.112701.142822",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014192044"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1080/13550280290049615",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014940872",
"https://doi.org/10.1080/13550280290049615"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/(sici)1098-1136(199801)22:1<72::aid-glia7>3.0.co;2-a",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015029368"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1365-2990.1995.tb01052.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016022966"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ana.410210513",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017093329"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0002-9440(10)65013-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018307960"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ana.410440521",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019135443"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jama.291.3.317",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019787735"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm0197-42",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020248609",
"https://doi.org/10.1038/nm0197-42"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1097/01.lab.0000107008.13321.c8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020365606",
"https://doi.org/10.1097/01.lab.0000107008.13321.c8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1080/13550280390201704",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020884329",
"https://doi.org/10.1080/13550280390201704"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0042-6822(91)90072-j",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021196560"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.95.24.14500",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021770209"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1080/135502801753248114",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021871650",
"https://doi.org/10.1080/135502801753248114"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/jnr.10762",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023029736"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.252469399",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023305950"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.0404842101",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023719219"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002030-200209060-00003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023957229"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002030-200209060-00003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023957229"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002030-200209060-00003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023957229"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ana.20198",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024291722"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1460-9568.1995.tb01124.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024587480"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1460-9568.1995.tb01124.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024587480"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0923-2516(98)80083-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024761926"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0165-5728(99)00049-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024773427"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jvi.76.18.9407-9419.2002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025528525"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1080/13550280490505382",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027110755",
"https://doi.org/10.1080/13550280490505382"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/bbrc.2000.3160",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027582589"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0006-8993(02)03731-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027805014"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jvi.78.12.6567-6584.2004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028193984"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/jnr.490280213",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028421563"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/978-3-7091-6781-6_11",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028828647",
"https://doi.org/10.1007/978-3-7091-6781-6_11"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/978-3-7091-6781-6_11",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028828647",
"https://doi.org/10.1007/978-3-7091-6781-6_11"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jvi.77.22.12140-12151.2003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028846247"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002030-199509000-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028960621"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002030-199509000-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028960621"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jvi.76.13.6689-6700.2002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030617578"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ana.410390606",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030997709"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nn1127",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032204781",
"https://doi.org/10.1038/nn1127"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nn1127",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032204781",
"https://doi.org/10.1038/nn1127"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1189/jlb.0303114",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032345153"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.cdd.4401344",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032653772",
"https://doi.org/10.1038/sj.cdd.4401344"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.cdd.4401344",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032653772",
"https://doi.org/10.1038/sj.cdd.4401344"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0002-9440(10)63767-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032725770"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1365-3083.1998.00422.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032901176"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1460-9568.2000.00894.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033437281"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0165-5728(93)90214-j",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033663776"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0165-5728(93)90214-j",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033663776"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00005072-199409000-00008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033749710"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0960-9822(98)70230-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034093618"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00705-003-0252-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034275556",
"https://doi.org/10.1007/s00705-003-0252-0"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/bbrc.2000.3113",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034687338"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1086/323478",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035018870"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.92.20.9328",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035181116"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0006-8993(95)01197-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035351849"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jvi.74.16.7211-7220.2000",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035627640"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0304-3940(01)01699-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035896175"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0165-5728(00)00454-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036387257"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ana.410290207",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036436288"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.virol.2004.03.003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036768906"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002030-199712000-00006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037096984"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002030-199712000-00006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037096984"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0923-2516(91)90051-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037735855"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0923-2516(91)90051-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037735855"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/viro.1999.9998",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037934936"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/(sici)1097-4547(20000301)59:5<671::aid-jnr10>3.0.co;2-b",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037985218"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ana.410310402",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038858368"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/322130a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038985416",
"https://doi.org/10.1038/322130a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1023/a:1014890219513",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039212034",
"https://doi.org/10.1023/a:1014890219513"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jvi.74.19.8904-8912.2000",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039728786"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0002-9440(10)65542-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040601831"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1084/jem.193.8.905",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041224337"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1080/13550280290049552",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041486946",
"https://doi.org/10.1080/13550280290049552"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1074/jbc.m311766200",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041565287"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.qai.0000030047.72209.d3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041671589"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.qai.0000030047.72209.d3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041671589"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.95.6.3117",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042138569"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1172/jci11916",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042477799"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0014-5793(98)01384-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043266588"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1182/blood.v97.2.352",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043404218"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/exmp.2000.2336",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044192664"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0042-6822(85)90246-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044421010"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.93.2.700",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044528471"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ana.410330604",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045141768"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00005072-199309000-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045544699"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0165-5728(00)00285-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045628615"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/smim.1999.0168",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045904700"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0896-6273(94)90159-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046243498"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0046-8177(85)80245-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046494453"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ana.410380510",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046544323"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jvi.74.20.9717-9726.2000",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047580397"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.83.18.7089",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047875933"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jvi.75.10.4681-4691.2001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047937801"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0306-4522(98)00163-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048438510"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jvi.76.12.6277-6292.2002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048544012"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0046-8177(83)80220-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048641793"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1182/blood.v98.3.541",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049364445"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1084/jem.20022156",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049442305"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0301-0082(02)00010-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049456115"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1074/jbc.273.36.23169",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049571006"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0165-0173(94)00015-h",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049576312"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00005072-199205000-00002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049913895"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.090017497",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050095348"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1074/jbc.271.16.9778",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051165131"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1080/13550280390194109",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052280988",
"https://doi.org/10.1080/13550280390194109"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.090576697",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053107295"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1074/jbc.m311164200",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053176771"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1089/088922299309973",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1059200253"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1089/088922299310719",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1059200327"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1089/104454902760330228",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1059203777"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1089/aid.1996.12.477",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1059224356"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002030-199901140-00003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1060144191"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002030-199901140-00003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1060144191"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002030-199901140-00003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1060144191"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.1098632",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062449686"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.2200125",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062527217"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.287.5453.602",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062568160"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000034175.11956.79",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064344741"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000034175.11956.79",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064344741"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000034175.11956.79",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064344741"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/wnl.42.9.1736",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064371018"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/wnl.52.3.607",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064377197"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/wnl.52.3.607",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064377197"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/wnl.52.3.607",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064377197"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.3109/13550289809114531",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1070986068",
"https://doi.org/10.3109/13550289809114531"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf03402144",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1074358632",
"https://doi.org/10.1007/bf03402144"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1074494571",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1074494572",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1074519440",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1074690739",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1523/jneurosci.21-06-02058.2001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1074782274"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.4049/jimmunol.167.9.5429",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1074944341"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1523/jneurosci.22-07-j0001.2002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1075021312"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1523/jneurosci.22-10-04015.2002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1075055428"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1075299309",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1077306572",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082478050",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082490945",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082520380",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082555606",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082571181",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/jlb.56.6.732",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1082600735"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082682847",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082795355",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082858419",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/cmr.9.1.100",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1082899603"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1523/jneurosci.16-13-04080.1996",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1082938446"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082989513",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082995544",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1083045568",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1083056590",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1083115719",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1523/jneurosci.17-17-06522.1997",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083129025"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1083169014",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1083194194",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1523/jneurosci.18-05-01633.1998",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083211640"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1083227079",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1083249132",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1083359361",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1083371765",
"type": "CreativeWork"
}
],
"datePublished": "2005-01",
"datePublishedReg": "2005-01-01",
"description": "HIV-associated dementia (HAD) is an important complication of the central nervous system in patients who are infected with HIV-1. Although the incidence of HAD has markedly decreased since it has become possible to effectively control viral replication in the blood by administering highly active antiretroviral therapy, a less severe form of HAD, comprising a milder cognitive and motor disorder, is now potentially a serious problem. Brain macrophages and microglia are the key cell types that are infected by HIV-1 in the central nervous system, and they are likely to mediate the neurodegeneration seen in patients with HAD; however, the precise pathogenesis of this neurodegeneration is still unclear. Here, we discuss the studies that are being carried out to determine the respective contributions of infection, and monocyte and macrophage activation, to disease progression.",
"genre": "research_article",
"id": "sg:pub.10.1038/nri1527",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1029717",
"issn": [
"1474-1733",
"1474-1741"
],
"name": "Nature Reviews Immunology",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "5"
}
],
"name": "The neuropathogenesis of AIDS",
"pagination": "69-81",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"094cbcdaa031f6d4591c836d6115c3dcf5b18cc9cc5833d09c973895b8c10ae0"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"15630430"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101124169"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/nri1527"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1001952502"
]
}
],
"sameAs": [
"https://doi.org/10.1038/nri1527",
"https://app.dimensions.ai/details/publication/pub.1001952502"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T12:12",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000361_0000000361/records_53990_00000000.jsonl",
"type": "ScholarlyArticle",
"url": "http://www.nature.com/nri/journal/v5/n1/full/nri1527.html"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nri1527'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nri1527'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nri1527'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nri1527'
This table displays all metadata directly associated to this object as RDF triples.
634 TRIPLES
21 PREDICATES
214 URIs
33 LITERALS
21 BLANK NODES