Immunoregulation in the tissues by γδ T cells View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2003-03

AUTHORS

Adrian Hayday, Robert Tigelaar

ABSTRACT

For a T-cell subset to be classified as immunoregulatory, it might reasonably be predicted that in its absence, animals would experience pathological immune dysregulation. Moreover, reconstitution of the subset should restore normal immune regulation. So far, these criteria have been satisfied by only a few of the candidate regulatory T-cell subsets, but among them is the intraepithelial gammadelta T-cell receptor (TCR)+ subset of mouse skin. In this article, we look at immunoregulatory gammadelta T cells, and the growing evidence for tissue-associated immunoregulation mediated by both gammadelta T cells and alphabeta T cells. More... »

PAGES

233-242

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nri1030

DOI

http://dx.doi.org/10.1038/nri1030

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003971889

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12658271


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