RNA-binding proteins in immune regulation: a focus on CCCH zinc finger proteins View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-02

AUTHORS

Mingui Fu, Perry J. Blackshear

ABSTRACT

Nearly 60 CCCH zinc finger proteins have been identified in humans and mice. These proteins are involved in the regulation of multiple steps of RNA metabolism, including mRNA splicing, polyadenylation, transportation, translation and decay. Several CCCH zinc finger proteins, such as tristetraprolin (TTP), roquin 1 and MCPIP1 (also known as regnase 1), are crucial for many aspects of immune regulation by targeting mRNAs for degradation and modulation of signalling pathways. In this Review, we focus on the emerging roles of CCCH zinc finger proteins in the regulation of immune responses through their effects on cytokine production, immune cell activation and immune homeostasis. More... »

PAGES

130-143

References to SciGraph publications

  • 2007-11. Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA in NATURE
  • 2014-08. The ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2014-06. Post-transcriptional regulation of gene expression in innate immunity in NATURE REVIEWS IMMUNOLOGY
  • 2009-09. TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis in NATURE IMMUNOLOGY
  • 2011-12. The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR–IL-1R by controlling degradation of regnase-1 in NATURE IMMUNOLOGY
  • 2009-04. Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay in NATURE
  • 2010-08. Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression in NATURE IMMUNOLOGY
  • 2008-10. Tristetraprolin (TTP) gene polymorphisms in patients with rheumatoid arthritis and healthy individuals in MODERN RHEUMATOLOGY
  • 2008-12. Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice in BMC GENOMICS
  • 2014-06. Post-transcriptional coordination of immunological responses by RNA-binding proteins in NATURE IMMUNOLOGY
  • 2014-11. Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote TH17 differentiation in NATURE IMMUNOLOGY
  • 2015-09. Synchronizing transcriptional control of T cell metabolism and function in NATURE REVIEWS IMMUNOLOGY
  • 2013-05. Targeted disruption of MCPIP1/Zc3h12a results in fatal inflammatory disease in IMMUNOLOGY AND CELL BIOLOGY
  • 2015-12. RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway in NATURE COMMUNICATIONS
  • 2014-08. Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2009-06. RNA granules: post-transcriptional and epigenetic modulators of gene expression in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2012-06. Follicular helper T cells in immunity and systemic autoimmunity in NATURE REVIEWS RHEUMATOLOGY
  • 2006-08. Auxiliary splice factor U2AF26 and transcription factor Gfi1 cooperate directly in regulating CD45 alternative splicing in NATURE IMMUNOLOGY
  • 2010-04. Interleukin‐6 as a Therapeutic Target in Candidate Inflammatory Diseases in CLINICAL PHARMACOLOGY & THERAPEUTICS
  • 2015-12. Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis in NATURE COMMUNICATIONS
  • 2004-03. Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2005-05. A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity in NATURE
  • 2009-12. Dysregulation of germinal centres in autoimmune disease in NATURE REVIEWS IMMUNOLOGY
  • 2013-04. Transcriptional regulation of tristetraprolin by NF-κB signaling in LPS-stimulated macrophages in MOLECULAR BIOLOGY REPORTS
  • 2015-12. New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins in SCIENTIFIC REPORTS
  • 2016-04. Structural basis for the regulation of enzymatic activity of Regnase-1 by domain-domain interactions in SCIENTIFIC REPORTS
  • 2008-04. Post-transcriptional control of cytokine production in NATURE IMMUNOLOGY
  • 2013-06. Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by tristetraprolin in NATURE STRUCTURAL & MOLECULAR BIOLOGY
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    URI

    http://scigraph.springernature.com/pub.10.1038/nri.2016.129

    DOI

    http://dx.doi.org/10.1038/nri.2016.129

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1046329564

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27990022


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