Effective population size and patterns of molecular evolution and variation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-03

AUTHORS

Brian Charlesworth

ABSTRACT

The effective size of a population, N(e), determines the rate of change in the composition of a population caused by genetic drift, which is the random sampling of genetic variants in a finite population. N(e) is crucial in determining the level of variability in a population, and the effectiveness of selection relative to drift. This article reviews the properties of N(e) in a variety of different situations of biological interest, and the factors that influence it. In particular, the action of selection means that N(e) varies across the genome, and advances in genomic techniques are giving new insights into how selection shapes N(e). More... »

PAGES

195-205

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrg2526

    DOI

    http://dx.doi.org/10.1038/nrg2526

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1032197557

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19204717


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