Long non-coding RNAs: insights into functions View Full Text


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Article Info

DATE

2009-03

AUTHORS

Tim R Mercer, Marcel E Dinger, John S Mattick

ABSTRACT

In mammals and other eukaryotes most of the genome is transcribed in a developmentally regulated manner to produce large numbers of long non-coding RNAs (ncRNAs). Here we review the rapidly advancing field of long ncRNAs, describing their conservation, their organization in the genome and their roles in gene regulation. We also consider the medical implications, and the emerging recognition that any transcript, regardless of coding potential, can have an intrinsic function as an RNA. More... »

PAGES

155-159

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrg2521

    DOI

    http://dx.doi.org/10.1038/nrg2521

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19188922


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