Genome–wide association studies provide new insights into type 2 diabetes aetiology View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-09

AUTHORS

Timothy M Frayling

ABSTRACT

Human geneticists are currently in the middle of a race. Thanks to a new technology in the form of 'genome-wide chips', investigators can potentially find many novel disease genes in one large experiment. Type 2 diabetes has been hot out of the blocks with six recent publications that together provide convincing evidence for six new gene regions involved in the condition. Together with candidate approaches, these studies have identified 11 confirmed genomic regions that alter the risk of type 2 diabetes in the European population. One of these regions, the fat mass and obesity associated gene (FTO), represents by far the best example of an association between common variation and fat mass in the general population. More... »

PAGES

657-662

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nrg2178

DOI

http://dx.doi.org/10.1038/nrg2178

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1002495423

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17703236


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