The cutting-edge of mammalian development; how the embryo makes teeth View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-07

AUTHORS

Abigail Tucker, Paul Sharpe

ABSTRACT

A wealth of information has recently become available on the molecular signals that are required to form and pattern the dentition in the mouse, shedding light on how important decisions about tooth shape, tooth number and cusp (cone-shaped prominence) number are generated. This information, which has been gleaned principally from knockout mice and manipulation of organ cultures, has been used to identify the genes and developmental processes that underlie the many human disorders in which tooth development is defective. Mouse models of several of these syndromes have also indicated ways in which such conditions could be treated. More... »

PAGES

499-508

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrg1380

    DOI

    http://dx.doi.org/10.1038/nrg1380

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1013371506

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/15211352


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