Systematic genome-wide screens of gene function View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-01

AUTHORS

Anne E Carpenter, David M Sabatini

ABSTRACT

By using genome information to create tools for perturbing gene function, it is now possible to undertake systematic genome-wide functional screens that examine the contribution of every gene to a biological process. The directed nature of these experiments contrasts with traditional methods, in which random mutations are induced and the resulting mutants are screened for various phenotypes. The first genome-wide functional screens in Caenorhabditis elegans and Drosophila melanogaster have recently been published, and screens in human cells will soon follow. These high-throughput techniques promise the rapid annotation of genomes with high-quality information about the biological function of each gene. More... »

PAGES

11-22

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    URI

    http://scigraph.springernature.com/pub.10.1038/nrg1248

    DOI

    http://dx.doi.org/10.1038/nrg1248

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/14708012


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    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nrg1248'


     

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