Microbial genetics: Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation View Full Text


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Article Info

DATE

2003-06

AUTHORS

Santiago F Elena, Richard E Lenski

ABSTRACT

Microorganisms have been mutating and evolving on Earth for billions of years. Now, a field of research has developed around the idea of using microorganisms to study evolution in action. Controlled and replicated experiments are using viruses, bacteria and yeast to investigate how their genomes and phenotypic properties evolve over hundreds and even thousands of generations. Here, we examine the dynamics of evolutionary adaptation, the genetic bases of adaptation, tradeoffs and the environmental specificity of adaptation, the origin and evolutionary consequences of mutators, and the process of drift decay in very small populations. More... »

PAGES

457-469

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrg1088

    DOI

    http://dx.doi.org/10.1038/nrg1088

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1008567554

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/12776215


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