Advances in the follow-up of differentiated or medullary thyroid cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-08

AUTHORS

Rossella Elisei, Aldo Pinchera

ABSTRACT

The long-term survival of patients with thyroid cancer and the possibility of tumour recurrence up to 30-40 years after the achievement of a disease-free status illustrate the importance of lifelong follow-up in these individuals. This Review discusses the most innovative aspects of follow-up protocols for patients with differentiated thyroid cancer, that is, of papillary or follicular hystotype, and those with medullary thyroid cancer. Particular focus is placed on the relevance of new ultrasensitive assays for thyroglobulin measurement and the option of using recombinant human TSH to stimulate thyroglobulin secretion. Methods to compensate for the loss of diagnostic significance of serum thyroglobulin levels in patients with differentiated thyroid cancer and circulating anti-thyroglobulin antibodies are highlighted, as well as the role of the postoperative calcitonin stimulation test and the clinical relevance of determining the doubling time of calcitonin and carcinoembryonic antigen in patients with medullary thyroid cancer. Moreover, this Review gives some insights into the role of molecular thyroid cancer testing, both for prognostic and for therapeutic purposes. Finally, a general overview of traditional imaging procedures, such as neck ultrasonography, CT, MRI and bone scintigraphy, is provided alongside a comparison with new nuclear imaging tests such as PET. More... »

PAGES

466

References to SciGraph publications

  • 2008-04. Technology Insight: measuring thyroglobulin and thyroglobulin autoantibody in patients with differentiated thyroid cancer in NATURE REVIEWS ENDOCRINOLOGY
  • 2007-07. Iodine-123 as a diagnostic imaging agent in differentiated thyroid carcinoma: a comparison with iodine-131 post-treatment scanning and serum thyroglobulin measurement in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2011-04. Targeted therapies for thyroid tumors in MODERN PATHOLOGY
  • 2009-06. The value of 18F-DOPA PET-CT in patients with medullary thyroid carcinoma: comparison with 18F-FDG PET-CT in EUROPEAN RADIOLOGY
  • 2009-06. Correlation of RET somatic mutations with clinicopathological features in sporadic medullary thyroid carcinomas in BRITISH JOURNAL OF CANCER
  • 2012-04. Comparison of 18F-DOPA, 18F-FDG and 68Ga-somatostatin analogue PET/CT in patients with recurrent medullary thyroid carcinoma in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2003-05. Long-term outcome of medullary thyroid carcinoma in patients with normal postoperative medical imaging in BRITISH JOURNAL OF CANCER
  • 2011-09. The use of ultrasensitive thyroglobulin assays reduces but does not abolish the need for TSH stimulation in patients with differentiated thyroid carcinoma in JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
  • 2011-06. Thyroid nodule guidelines: agreement, disagreement and need for future research in NATURE REVIEWS ENDOCRINOLOGY
  • 2011-12. Factors determining the persistence or recurrence of well-differentiated thyroid cancer treated by thyroidectomy and/or radioiodine in the Boston, Massachusetts area: A retrospective chart review in THYROID RESEARCH
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrendo.2012.38

    DOI

    http://dx.doi.org/10.1038/nrendo.2012.38

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1000559689

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22473335


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Oncology and Carcinogenesis", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adenocarcinoma, Follicular", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Calcitonin", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Carcinoembryonic Antigen", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Carcinoma", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Carcinoma, Neuroendocrine", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Carcinoma, Papillary", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Follow-Up Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Prognosis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Survival Rate", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Thyroglobulin", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Thyroid Neoplasms", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "University of Pisa", 
              "id": "https://www.grid.ac/institutes/grid.5395.a", 
              "name": [
                "Department of Endocrinology and Metabolism, University of Pisa, 2 Via Paradisa, 56124 Pisa, Italy"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Elisei", 
            "givenName": "Rossella", 
            "id": "sg:person.013417777464.53", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013417777464.53"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Pisa", 
              "id": "https://www.grid.ac/institutes/grid.5395.a", 
              "name": [
                "Department of Endocrinology and Metabolism, University of Pisa, 2 Via Paradisa, 56124 Pisa, Italy"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pinchera", 
            "givenName": "Aldo", 
            "id": "sg:person.01344402654.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344402654.02"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/s0025-6196(12)60923-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001110343"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1586/14737159.8.1.83", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001197889"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2967/jnumed.111.094771", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001599371"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.59.4.1216", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002831845"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00006231-200409000-00006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004786856"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00006231-200409000-00006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004786856"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/modpathol.2010.165", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004949911", 
              "https://doi.org/10.1038/modpathol.2010.165"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00259-011-2031-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005190218", 
              "https://doi.org/10.1007/s00259-011-2031-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1530/eje.1.02158", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005439988"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2967/jnumed.106.036681", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006149788"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1677/erc-08-0152", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006183971"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cncr.11031", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008036571"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2005-0492", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008383442"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1530/eje.0.1480589", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014782360"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1530/eje.0.1480589", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014782360"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1530/eje.0.1480589", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014782360"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00259-006-0341-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014939890", 
              "https://doi.org/10.1007/s00259-006-0341-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00259-006-0341-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014939890", 
              "https://doi.org/10.1007/s00259-006-0341-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/thy.2009.0110", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018764357"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.remn.2009.12.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023344308"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1373/clinchem.2010.151688", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025044372"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1365-2265.2001.01175.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025804778"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.clon.2010.05.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027507883"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000322640", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030879980"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1530/acta.0.1190373", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031538361"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejm199801293380506", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032016310"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/ajcp/95.3.300", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035042289"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00330-008-1280-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035418102", 
              "https://doi.org/10.1007/s00330-008-1280-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00330-008-1280-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035418102", 
              "https://doi.org/10.1007/s00330-008-1280-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1365-2265.2001.01339.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040084449"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0000816", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042645705"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1756-6614-4-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048423105", 
              "https://doi.org/10.1186/1756-6614-4-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ncpendmet0757", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048971339", 
              "https://doi.org/10.1038/ncpendmet0757"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.bjc.6605056", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049580708", 
              "https://doi.org/10.1038/sj.bjc.6605056"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.bjc.6605056", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049580708", 
              "https://doi.org/10.1038/sj.bjc.6605056"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.bjc.6600930", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049967756", 
              "https://doi.org/10.1038/sj.bjc.6600930"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.bjc.6600930", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049967756", 
              "https://doi.org/10.1038/sj.bjc.6600930"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2265.2009.03666.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050426992"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2265.2009.03666.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050426992"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrendo.2011.1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050987308", 
              "https://doi.org/10.1038/nrendo.2011.1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/02841868009130138", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052447880"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/108497804773391694", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059207924"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/thy.2008.0403", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059320443"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/thy.2009.0266", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059320626"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/thy.2010.0355", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059320910"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/thy.2010.0355", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059320910"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/thy.2011.0010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059321121"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/thy.2011.2107.ed1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059321340"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/thy.2011.2107.ed1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059321340"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/pdb.prot5138", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060411039"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.102.162503", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060755230"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.102.162503", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060755230"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/er.2007-0007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064285893"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2002-021702", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064286497"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2003-030838", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064287032"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2003-031341", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064287234"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2003-031521", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064287304"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2005-0044", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064288286"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2005-1534", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064288691"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2006-0723", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064289254"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2006-2088", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064289607"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2007-0444", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064289922"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2007-1005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064290049"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2007-1211", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064290089"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2007-1404", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064290138"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2007-1714", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064290203"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2008-0607", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064290646"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2008-0962", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064290736"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2008-2403", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064291087"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2009-1354", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064291541"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2010-1921", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064292413"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2010-2695", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064292569"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2010-2708", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064292574"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2011-2033", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064293041"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.74.6.1401", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064296335"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.77.4.1090", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064297098"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.80.5.1488", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064298216"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.85.10.3623", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064301075"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jcem.74.6.1592886", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064317583"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jcem.77.4.8408458", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064318358"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jcem.80.5.7744991", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064319506"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jcem.85.1.6310", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064323011"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jcem.86.12.8065", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064324040"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jcem.86.9.7831", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064324742"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jcem.87.4.8274", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064325073"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7326/0003-4819-139-5_part_1-200309020-00010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1073706516"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074607950", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077824268", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078295114", 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.3275/7571", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1078363252", 
              "https://doi.org/10.3275/7571"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1079893975", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/172460089400900104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1082627704"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/172460089400900104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1082627704"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2012-08", 
        "datePublishedReg": "2012-08-01", 
        "description": "The long-term survival of patients with thyroid cancer and the possibility of tumour recurrence up to 30-40 years after the achievement of a disease-free status illustrate the importance of lifelong follow-up in these individuals. This Review discusses the most innovative aspects of follow-up protocols for patients with differentiated thyroid cancer, that is, of papillary or follicular hystotype, and those with medullary thyroid cancer. Particular focus is placed on the relevance of new ultrasensitive assays for thyroglobulin measurement and the option of using recombinant human TSH to stimulate thyroglobulin secretion. Methods to compensate for the loss of diagnostic significance of serum thyroglobulin levels in patients with differentiated thyroid cancer and circulating anti-thyroglobulin antibodies are highlighted, as well as the role of the postoperative calcitonin stimulation test and the clinical relevance of determining the doubling time of calcitonin and carcinoembryonic antigen in patients with medullary thyroid cancer. Moreover, this Review gives some insights into the role of molecular thyroid cancer testing, both for prognostic and for therapeutic purposes. Finally, a general overview of traditional imaging procedures, such as neck ultrasonography, CT, MRI and bone scintigraphy, is provided alongside a comparison with new nuclear imaging tests such as PET.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1038/nrendo.2012.38", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1345278", 
            "issn": [
              "1759-5029", 
              "1759-5037"
            ], 
            "name": "Nature Reviews Endocrinology", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "8", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "8"
          }
        ], 
        "name": "Advances in the follow-up of differentiated or medullary thyroid cancer", 
        "pagination": "466", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "02aa095e07b280e5fce4d1b6b8c77c7ec5f863355837891862339e971142bc77"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "22473335"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "101500078"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/nrendo.2012.38"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1000559689"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/nrendo.2012.38", 
          "https://app.dimensions.ai/details/publication/pub.1000559689"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-10T21:26", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8687_00000436.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://www.nature.com/articles/nrendo.2012.38"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nrendo.2012.38'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nrendo.2012.38'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nrendo.2012.38'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nrendo.2012.38'


     

    This table displays all metadata directly associated to this object as RDF triples.

    373 TRIPLES      21 PREDICATES      122 URIs      33 LITERALS      21 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/nrendo.2012.38 schema:about N1ffc53cf2b7446c2bf1b717583d1af10
    2 N29d176fb64fa41358ec46cf4c37b2f90
    3 N2b67b811e4fa4aec96770d7620dbd911
    4 N3758bef7b44f4070912558d7aa86c611
    5 N41b9ebd4d4374abb85cc6fe0d72e4b0a
    6 N44bed0002e984ffc9ef06d9aaa64f216
    7 N4ec64f5f52524eff93afc510849bb0b7
    8 Na79300cf28f84d29a81b9a73dc920005
    9 Nba88bdc74c5b4557b49829cf41eafe62
    10 Nca5e7c7d46e14a97a69fa7f24ebbd5be
    11 Ne60e56396a9e4a1aa53248581ac3300f
    12 Nf2600ca2f319432390d2123d66e611d2
    13 anzsrc-for:11
    14 anzsrc-for:1112
    15 schema:author N4bb2b54f8e74458cb858bdd8d8f7b2a4
    16 schema:citation sg:pub.10.1007/s00259-006-0341-x
    17 sg:pub.10.1007/s00259-011-2031-6
    18 sg:pub.10.1007/s00330-008-1280-7
    19 sg:pub.10.1038/modpathol.2010.165
    20 sg:pub.10.1038/ncpendmet0757
    21 sg:pub.10.1038/nrendo.2011.1
    22 sg:pub.10.1038/sj.bjc.6600930
    23 sg:pub.10.1038/sj.bjc.6605056
    24 sg:pub.10.1186/1756-6614-4-9
    25 sg:pub.10.3275/7571
    26 https://app.dimensions.ai/details/publication/pub.1074607950
    27 https://app.dimensions.ai/details/publication/pub.1077824268
    28 https://app.dimensions.ai/details/publication/pub.1078295114
    29 https://app.dimensions.ai/details/publication/pub.1079893975
    30 https://doi.org/10.1002/cncr.11031
    31 https://doi.org/10.1016/j.clon.2010.05.002
    32 https://doi.org/10.1016/j.remn.2009.12.010
    33 https://doi.org/10.1016/s0025-6196(12)60923-9
    34 https://doi.org/10.1046/j.1365-2265.2001.01175.x
    35 https://doi.org/10.1046/j.1365-2265.2001.01339.x
    36 https://doi.org/10.1056/nejm199801293380506
    37 https://doi.org/10.1073/pnas.59.4.1216
    38 https://doi.org/10.1089/108497804773391694
    39 https://doi.org/10.1089/thy.2008.0403
    40 https://doi.org/10.1089/thy.2009.0110
    41 https://doi.org/10.1089/thy.2009.0266
    42 https://doi.org/10.1089/thy.2010.0355
    43 https://doi.org/10.1089/thy.2011.0010
    44 https://doi.org/10.1089/thy.2011.2107.ed1
    45 https://doi.org/10.1093/ajcp/95.3.300
    46 https://doi.org/10.1097/00006231-200409000-00006
    47 https://doi.org/10.1101/pdb.prot5138
    48 https://doi.org/10.1103/physrevlett.102.162503
    49 https://doi.org/10.1111/j.1365-2265.2009.03666.x
    50 https://doi.org/10.1159/000322640
    51 https://doi.org/10.1177/172460089400900104
    52 https://doi.org/10.1210/er.2007-0007
    53 https://doi.org/10.1210/jc.2002-021702
    54 https://doi.org/10.1210/jc.2003-030838
    55 https://doi.org/10.1210/jc.2003-031341
    56 https://doi.org/10.1210/jc.2003-031521
    57 https://doi.org/10.1210/jc.2005-0044
    58 https://doi.org/10.1210/jc.2005-0492
    59 https://doi.org/10.1210/jc.2005-1534
    60 https://doi.org/10.1210/jc.2006-0723
    61 https://doi.org/10.1210/jc.2006-2088
    62 https://doi.org/10.1210/jc.2007-0444
    63 https://doi.org/10.1210/jc.2007-1005
    64 https://doi.org/10.1210/jc.2007-1211
    65 https://doi.org/10.1210/jc.2007-1404
    66 https://doi.org/10.1210/jc.2007-1714
    67 https://doi.org/10.1210/jc.2008-0607
    68 https://doi.org/10.1210/jc.2008-0962
    69 https://doi.org/10.1210/jc.2008-2403
    70 https://doi.org/10.1210/jc.2009-1354
    71 https://doi.org/10.1210/jc.2010-1921
    72 https://doi.org/10.1210/jc.2010-2695
    73 https://doi.org/10.1210/jc.2010-2708
    74 https://doi.org/10.1210/jc.2011-2033
    75 https://doi.org/10.1210/jc.74.6.1401
    76 https://doi.org/10.1210/jc.77.4.1090
    77 https://doi.org/10.1210/jc.80.5.1488
    78 https://doi.org/10.1210/jc.85.10.3623
    79 https://doi.org/10.1210/jcem.74.6.1592886
    80 https://doi.org/10.1210/jcem.77.4.8408458
    81 https://doi.org/10.1210/jcem.80.5.7744991
    82 https://doi.org/10.1210/jcem.85.1.6310
    83 https://doi.org/10.1210/jcem.86.12.8065
    84 https://doi.org/10.1210/jcem.86.9.7831
    85 https://doi.org/10.1210/jcem.87.4.8274
    86 https://doi.org/10.1371/journal.pone.0000816
    87 https://doi.org/10.1373/clinchem.2010.151688
    88 https://doi.org/10.1530/acta.0.1190373
    89 https://doi.org/10.1530/eje.0.1480589
    90 https://doi.org/10.1530/eje.1.02158
    91 https://doi.org/10.1586/14737159.8.1.83
    92 https://doi.org/10.1677/erc-08-0152
    93 https://doi.org/10.2967/jnumed.106.036681
    94 https://doi.org/10.2967/jnumed.111.094771
    95 https://doi.org/10.3109/02841868009130138
    96 https://doi.org/10.7326/0003-4819-139-5_part_1-200309020-00010
    97 schema:datePublished 2012-08
    98 schema:datePublishedReg 2012-08-01
    99 schema:description The long-term survival of patients with thyroid cancer and the possibility of tumour recurrence up to 30-40 years after the achievement of a disease-free status illustrate the importance of lifelong follow-up in these individuals. This Review discusses the most innovative aspects of follow-up protocols for patients with differentiated thyroid cancer, that is, of papillary or follicular hystotype, and those with medullary thyroid cancer. Particular focus is placed on the relevance of new ultrasensitive assays for thyroglobulin measurement and the option of using recombinant human TSH to stimulate thyroglobulin secretion. Methods to compensate for the loss of diagnostic significance of serum thyroglobulin levels in patients with differentiated thyroid cancer and circulating anti-thyroglobulin antibodies are highlighted, as well as the role of the postoperative calcitonin stimulation test and the clinical relevance of determining the doubling time of calcitonin and carcinoembryonic antigen in patients with medullary thyroid cancer. Moreover, this Review gives some insights into the role of molecular thyroid cancer testing, both for prognostic and for therapeutic purposes. Finally, a general overview of traditional imaging procedures, such as neck ultrasonography, CT, MRI and bone scintigraphy, is provided alongside a comparison with new nuclear imaging tests such as PET.
    100 schema:genre research_article
    101 schema:inLanguage en
    102 schema:isAccessibleForFree false
    103 schema:isPartOf N947b75d128d04b7aba8d1bd8f8640813
    104 Nad9d3dafd52d44468e24c76b5a8d1ff5
    105 sg:journal.1345278
    106 schema:name Advances in the follow-up of differentiated or medullary thyroid cancer
    107 schema:pagination 466
    108 schema:productId N3b31004956c54d4d89040af2241393a3
    109 N7d7e3797df2e415183114e20f2fdeef8
    110 Nc2abe6ebcd1e4f88be38b52dffa81833
    111 Nfa23969cd9aa4f54b3d260a664d528ae
    112 Nfe18548d9f334baa906a17f78e1a459b
    113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000559689
    114 https://doi.org/10.1038/nrendo.2012.38
    115 schema:sdDatePublished 2019-04-10T21:26
    116 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    117 schema:sdPublisher N33fd6ed85d8e4ca481af9cdbf9728c96
    118 schema:url https://www.nature.com/articles/nrendo.2012.38
    119 sgo:license sg:explorer/license/
    120 sgo:sdDataset articles
    121 rdf:type schema:ScholarlyArticle
    122 N1ffc53cf2b7446c2bf1b717583d1af10 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    123 schema:name Prognosis
    124 rdf:type schema:DefinedTerm
    125 N29d176fb64fa41358ec46cf4c37b2f90 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    126 schema:name Follow-Up Studies
    127 rdf:type schema:DefinedTerm
    128 N2b67b811e4fa4aec96770d7620dbd911 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    129 schema:name Carcinoembryonic Antigen
    130 rdf:type schema:DefinedTerm
    131 N33fd6ed85d8e4ca481af9cdbf9728c96 schema:name Springer Nature - SN SciGraph project
    132 rdf:type schema:Organization
    133 N3758bef7b44f4070912558d7aa86c611 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    134 schema:name Humans
    135 rdf:type schema:DefinedTerm
    136 N3b31004956c54d4d89040af2241393a3 schema:name pubmed_id
    137 schema:value 22473335
    138 rdf:type schema:PropertyValue
    139 N41b9ebd4d4374abb85cc6fe0d72e4b0a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    140 schema:name Survival Rate
    141 rdf:type schema:DefinedTerm
    142 N44bed0002e984ffc9ef06d9aaa64f216 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    143 schema:name Carcinoma, Papillary
    144 rdf:type schema:DefinedTerm
    145 N4bb2b54f8e74458cb858bdd8d8f7b2a4 rdf:first sg:person.013417777464.53
    146 rdf:rest Nebd55799f8fa4c61a5159e8efdbea663
    147 N4ec64f5f52524eff93afc510849bb0b7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    148 schema:name Thyroglobulin
    149 rdf:type schema:DefinedTerm
    150 N7d7e3797df2e415183114e20f2fdeef8 schema:name dimensions_id
    151 schema:value pub.1000559689
    152 rdf:type schema:PropertyValue
    153 N947b75d128d04b7aba8d1bd8f8640813 schema:volumeNumber 8
    154 rdf:type schema:PublicationVolume
    155 Na79300cf28f84d29a81b9a73dc920005 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    156 schema:name Adenocarcinoma, Follicular
    157 rdf:type schema:DefinedTerm
    158 Nad9d3dafd52d44468e24c76b5a8d1ff5 schema:issueNumber 8
    159 rdf:type schema:PublicationIssue
    160 Nba88bdc74c5b4557b49829cf41eafe62 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    161 schema:name Carcinoma
    162 rdf:type schema:DefinedTerm
    163 Nc2abe6ebcd1e4f88be38b52dffa81833 schema:name doi
    164 schema:value 10.1038/nrendo.2012.38
    165 rdf:type schema:PropertyValue
    166 Nca5e7c7d46e14a97a69fa7f24ebbd5be schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    167 schema:name Carcinoma, Neuroendocrine
    168 rdf:type schema:DefinedTerm
    169 Ne60e56396a9e4a1aa53248581ac3300f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    170 schema:name Calcitonin
    171 rdf:type schema:DefinedTerm
    172 Nebd55799f8fa4c61a5159e8efdbea663 rdf:first sg:person.01344402654.02
    173 rdf:rest rdf:nil
    174 Nf2600ca2f319432390d2123d66e611d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    175 schema:name Thyroid Neoplasms
    176 rdf:type schema:DefinedTerm
    177 Nfa23969cd9aa4f54b3d260a664d528ae schema:name readcube_id
    178 schema:value 02aa095e07b280e5fce4d1b6b8c77c7ec5f863355837891862339e971142bc77
    179 rdf:type schema:PropertyValue
    180 Nfe18548d9f334baa906a17f78e1a459b schema:name nlm_unique_id
    181 schema:value 101500078
    182 rdf:type schema:PropertyValue
    183 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    184 schema:name Medical and Health Sciences
    185 rdf:type schema:DefinedTerm
    186 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
    187 schema:name Oncology and Carcinogenesis
    188 rdf:type schema:DefinedTerm
    189 sg:journal.1345278 schema:issn 1759-5029
    190 1759-5037
    191 schema:name Nature Reviews Endocrinology
    192 rdf:type schema:Periodical
    193 sg:person.013417777464.53 schema:affiliation https://www.grid.ac/institutes/grid.5395.a
    194 schema:familyName Elisei
    195 schema:givenName Rossella
    196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013417777464.53
    197 rdf:type schema:Person
    198 sg:person.01344402654.02 schema:affiliation https://www.grid.ac/institutes/grid.5395.a
    199 schema:familyName Pinchera
    200 schema:givenName Aldo
    201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344402654.02
    202 rdf:type schema:Person
    203 sg:pub.10.1007/s00259-006-0341-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014939890
    204 https://doi.org/10.1007/s00259-006-0341-x
    205 rdf:type schema:CreativeWork
    206 sg:pub.10.1007/s00259-011-2031-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005190218
    207 https://doi.org/10.1007/s00259-011-2031-6
    208 rdf:type schema:CreativeWork
    209 sg:pub.10.1007/s00330-008-1280-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035418102
    210 https://doi.org/10.1007/s00330-008-1280-7
    211 rdf:type schema:CreativeWork
    212 sg:pub.10.1038/modpathol.2010.165 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004949911
    213 https://doi.org/10.1038/modpathol.2010.165
    214 rdf:type schema:CreativeWork
    215 sg:pub.10.1038/ncpendmet0757 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048971339
    216 https://doi.org/10.1038/ncpendmet0757
    217 rdf:type schema:CreativeWork
    218 sg:pub.10.1038/nrendo.2011.1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050987308
    219 https://doi.org/10.1038/nrendo.2011.1
    220 rdf:type schema:CreativeWork
    221 sg:pub.10.1038/sj.bjc.6600930 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049967756
    222 https://doi.org/10.1038/sj.bjc.6600930
    223 rdf:type schema:CreativeWork
    224 sg:pub.10.1038/sj.bjc.6605056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049580708
    225 https://doi.org/10.1038/sj.bjc.6605056
    226 rdf:type schema:CreativeWork
    227 sg:pub.10.1186/1756-6614-4-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048423105
    228 https://doi.org/10.1186/1756-6614-4-9
    229 rdf:type schema:CreativeWork
    230 sg:pub.10.3275/7571 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078363252
    231 https://doi.org/10.3275/7571
    232 rdf:type schema:CreativeWork
    233 https://app.dimensions.ai/details/publication/pub.1074607950 schema:CreativeWork
    234 https://app.dimensions.ai/details/publication/pub.1077824268 schema:CreativeWork
    235 https://app.dimensions.ai/details/publication/pub.1078295114 schema:CreativeWork
    236 https://app.dimensions.ai/details/publication/pub.1079893975 schema:CreativeWork
    237 https://doi.org/10.1002/cncr.11031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008036571
    238 rdf:type schema:CreativeWork
    239 https://doi.org/10.1016/j.clon.2010.05.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027507883
    240 rdf:type schema:CreativeWork
    241 https://doi.org/10.1016/j.remn.2009.12.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023344308
    242 rdf:type schema:CreativeWork
    243 https://doi.org/10.1016/s0025-6196(12)60923-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001110343
    244 rdf:type schema:CreativeWork
    245 https://doi.org/10.1046/j.1365-2265.2001.01175.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025804778
    246 rdf:type schema:CreativeWork
    247 https://doi.org/10.1046/j.1365-2265.2001.01339.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1040084449
    248 rdf:type schema:CreativeWork
    249 https://doi.org/10.1056/nejm199801293380506 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032016310
    250 rdf:type schema:CreativeWork
    251 https://doi.org/10.1073/pnas.59.4.1216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002831845
    252 rdf:type schema:CreativeWork
    253 https://doi.org/10.1089/108497804773391694 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059207924
    254 rdf:type schema:CreativeWork
    255 https://doi.org/10.1089/thy.2008.0403 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059320443
    256 rdf:type schema:CreativeWork
    257 https://doi.org/10.1089/thy.2009.0110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018764357
    258 rdf:type schema:CreativeWork
    259 https://doi.org/10.1089/thy.2009.0266 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059320626
    260 rdf:type schema:CreativeWork
    261 https://doi.org/10.1089/thy.2010.0355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059320910
    262 rdf:type schema:CreativeWork
    263 https://doi.org/10.1089/thy.2011.0010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059321121
    264 rdf:type schema:CreativeWork
    265 https://doi.org/10.1089/thy.2011.2107.ed1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059321340
    266 rdf:type schema:CreativeWork
    267 https://doi.org/10.1093/ajcp/95.3.300 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035042289
    268 rdf:type schema:CreativeWork
    269 https://doi.org/10.1097/00006231-200409000-00006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004786856
    270 rdf:type schema:CreativeWork
    271 https://doi.org/10.1101/pdb.prot5138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060411039
    272 rdf:type schema:CreativeWork
    273 https://doi.org/10.1103/physrevlett.102.162503 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060755230
    274 rdf:type schema:CreativeWork
    275 https://doi.org/10.1111/j.1365-2265.2009.03666.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050426992
    276 rdf:type schema:CreativeWork
    277 https://doi.org/10.1159/000322640 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030879980
    278 rdf:type schema:CreativeWork
    279 https://doi.org/10.1177/172460089400900104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082627704
    280 rdf:type schema:CreativeWork
    281 https://doi.org/10.1210/er.2007-0007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064285893
    282 rdf:type schema:CreativeWork
    283 https://doi.org/10.1210/jc.2002-021702 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064286497
    284 rdf:type schema:CreativeWork
    285 https://doi.org/10.1210/jc.2003-030838 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064287032
    286 rdf:type schema:CreativeWork
    287 https://doi.org/10.1210/jc.2003-031341 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064287234
    288 rdf:type schema:CreativeWork
    289 https://doi.org/10.1210/jc.2003-031521 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064287304
    290 rdf:type schema:CreativeWork
    291 https://doi.org/10.1210/jc.2005-0044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064288286
    292 rdf:type schema:CreativeWork
    293 https://doi.org/10.1210/jc.2005-0492 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008383442
    294 rdf:type schema:CreativeWork
    295 https://doi.org/10.1210/jc.2005-1534 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064288691
    296 rdf:type schema:CreativeWork
    297 https://doi.org/10.1210/jc.2006-0723 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064289254
    298 rdf:type schema:CreativeWork
    299 https://doi.org/10.1210/jc.2006-2088 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064289607
    300 rdf:type schema:CreativeWork
    301 https://doi.org/10.1210/jc.2007-0444 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064289922
    302 rdf:type schema:CreativeWork
    303 https://doi.org/10.1210/jc.2007-1005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064290049
    304 rdf:type schema:CreativeWork
    305 https://doi.org/10.1210/jc.2007-1211 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064290089
    306 rdf:type schema:CreativeWork
    307 https://doi.org/10.1210/jc.2007-1404 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064290138
    308 rdf:type schema:CreativeWork
    309 https://doi.org/10.1210/jc.2007-1714 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064290203
    310 rdf:type schema:CreativeWork
    311 https://doi.org/10.1210/jc.2008-0607 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064290646
    312 rdf:type schema:CreativeWork
    313 https://doi.org/10.1210/jc.2008-0962 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064290736
    314 rdf:type schema:CreativeWork
    315 https://doi.org/10.1210/jc.2008-2403 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064291087
    316 rdf:type schema:CreativeWork
    317 https://doi.org/10.1210/jc.2009-1354 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064291541
    318 rdf:type schema:CreativeWork
    319 https://doi.org/10.1210/jc.2010-1921 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064292413
    320 rdf:type schema:CreativeWork
    321 https://doi.org/10.1210/jc.2010-2695 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064292569
    322 rdf:type schema:CreativeWork
    323 https://doi.org/10.1210/jc.2010-2708 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064292574
    324 rdf:type schema:CreativeWork
    325 https://doi.org/10.1210/jc.2011-2033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064293041
    326 rdf:type schema:CreativeWork
    327 https://doi.org/10.1210/jc.74.6.1401 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064296335
    328 rdf:type schema:CreativeWork
    329 https://doi.org/10.1210/jc.77.4.1090 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064297098
    330 rdf:type schema:CreativeWork
    331 https://doi.org/10.1210/jc.80.5.1488 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064298216
    332 rdf:type schema:CreativeWork
    333 https://doi.org/10.1210/jc.85.10.3623 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064301075
    334 rdf:type schema:CreativeWork
    335 https://doi.org/10.1210/jcem.74.6.1592886 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064317583
    336 rdf:type schema:CreativeWork
    337 https://doi.org/10.1210/jcem.77.4.8408458 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064318358
    338 rdf:type schema:CreativeWork
    339 https://doi.org/10.1210/jcem.80.5.7744991 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064319506
    340 rdf:type schema:CreativeWork
    341 https://doi.org/10.1210/jcem.85.1.6310 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064323011
    342 rdf:type schema:CreativeWork
    343 https://doi.org/10.1210/jcem.86.12.8065 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064324040
    344 rdf:type schema:CreativeWork
    345 https://doi.org/10.1210/jcem.86.9.7831 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064324742
    346 rdf:type schema:CreativeWork
    347 https://doi.org/10.1210/jcem.87.4.8274 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064325073
    348 rdf:type schema:CreativeWork
    349 https://doi.org/10.1371/journal.pone.0000816 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042645705
    350 rdf:type schema:CreativeWork
    351 https://doi.org/10.1373/clinchem.2010.151688 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025044372
    352 rdf:type schema:CreativeWork
    353 https://doi.org/10.1530/acta.0.1190373 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031538361
    354 rdf:type schema:CreativeWork
    355 https://doi.org/10.1530/eje.0.1480589 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014782360
    356 rdf:type schema:CreativeWork
    357 https://doi.org/10.1530/eje.1.02158 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005439988
    358 rdf:type schema:CreativeWork
    359 https://doi.org/10.1586/14737159.8.1.83 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001197889
    360 rdf:type schema:CreativeWork
    361 https://doi.org/10.1677/erc-08-0152 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006183971
    362 rdf:type schema:CreativeWork
    363 https://doi.org/10.2967/jnumed.106.036681 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006149788
    364 rdf:type schema:CreativeWork
    365 https://doi.org/10.2967/jnumed.111.094771 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001599371
    366 rdf:type schema:CreativeWork
    367 https://doi.org/10.3109/02841868009130138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052447880
    368 rdf:type schema:CreativeWork
    369 https://doi.org/10.7326/0003-4819-139-5_part_1-200309020-00010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073706516
    370 rdf:type schema:CreativeWork
    371 https://www.grid.ac/institutes/grid.5395.a schema:alternateName University of Pisa
    372 schema:name Department of Endocrinology and Metabolism, University of Pisa, 2 Via Paradisa, 56124 Pisa, Italy
    373 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...