PPARγ: a circadian transcription factor in adipogenesis and osteogenesis View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-09-07

AUTHORS

Masanobu Kawai, Clifford J. Rosen

ABSTRACT

This Review focuses on new findings regarding the role of peroxisome proliferator-activated receptor γ (PPARγ) in adipose tissue and skeletal metabolism and summarizes the emerging role of PPARγ as an integral part of a complex circadian regulatory system that modulates food storage, energy consumption and skeletal metabolism.

PAGES

629-636

References to SciGraph publications

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  • 2007-12-02. PPAR-γ regulates osteoclastogenesis in mice in NATURE MEDICINE
  • 2007-10-21. A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-γ transactivation in NATURE CELL BIOLOGY
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  • 2007-05-02. Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism in NATURE
  • 2006-12-01. Adipocyte differentiation from the inside out in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2004-07-13. Enhanced Marrow Adipogenesis and Bone Resorption in Estrogen-Deprived Rats Treated with the PPARgamma Agonist BRL49653 (Rosiglitazone) in CALCIFIED TISSUE INTERNATIONAL
  • 2003-04. Endocrine responses to nocturnal eating – possible implications for night work in EUROPEAN JOURNAL OF NUTRITION
  • 2003-11-16. Muscle-specific Pparg deletion causes insulin resistance in NATURE MEDICINE
  • 2009-07-01. Insulin-like growth factor-I and bone: lessons from mice and men in PEDIATRIC NEPHROLOGY
  • 2007-02. Post-translational modifications regulate the ticking of the circadian clock in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2001-05-25. Rhythmic expression of NocturninmRNA in multiple tissues of the mouse in BMC DEVELOPMENTAL BIOLOGY
  • 2001-11-22. Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding in BMC GENOMICS
  • 2008-01-20. Dok1 mediates high-fat diet–induced adipocyte hypertrophy and obesity through modulation of PPAR-γ phosphorylation in NATURE MEDICINE
  • 2004-03-31. PPARs and the complex journey to obesity in NATURE MEDICINE
  • 2009-06-10. Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment in NATURE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrendo.2010.155

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    http://dx.doi.org/10.1038/nrendo.2010.155

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1015044801

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20820194


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