Obesity View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-06-15

AUTHORS

Pedro González-Muniesa, Miguel-Angel Mártinez-González, Frank B. Hu, Jean-Pierre Després, Yuji Matsuzawa, Ruth J. F. Loos, Luis A. Moreno, George A. Bray, J. Alfredo Martinez

ABSTRACT

Excessive fat deposition in obesity has a multifactorial aetiology, but is widely considered the result of disequilibrium between energy intake and expenditure. Despite specific public health policies and individual treatment efforts to combat the obesity epidemic, >2 billion people worldwide are overweight or obese. The central nervous system circuitry, fuel turnover and metabolism as well as adipose tissue homeostasis are important to comprehend excessive weight gain and associated comorbidities. Obesity has a profound impact on quality of life, even in seemingly healthy individuals. Diet, physical activity or exercise and lifestyle changes are the cornerstones of obesity treatment, but medical treatment and bariatric surgery are becoming important. Family history, food environment, cultural preferences, adverse reactions to food, perinatal nutrition, previous or current diseases and physical activity patterns are relevant aspects for the health care professional to consider when treating the individual with obesity. Clinicians and other health care professionals are often ill-equipped to address the important environmental and socioeconomic drivers of the current obesity epidemic. Finally, understanding the epigenetic and genetic factors as well as metabolic pathways that take advantage of 'omics' technologies could play a very relevant part in combating obesity within a precision approach. More... »

PAGES

nrdp201734

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nrdp.2017.34

DOI

http://dx.doi.org/10.1038/nrdp.2017.34

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1086031448

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28617414


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871 schema:name Centre de Recherche de l’Institut universitaire de Cardiologie et de Pneumologie de Québec, and Department of Kinesiology, Faculty of Medicine, Université Laval, Québec City, Québec, Canada.
872 rdf:type schema:Organization
873 https://www.grid.ac/institutes/grid.38142.3c schema:alternateName Harvard University
874 schema:name CIBERobn Physiopathology of Obesity and Nutrition, Centre of Biomedical Research Network, ISCIII, Madrid, Spain.
875 Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain.
876 Departments of Nutrition and Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
877 IDISNA Navarra's Health Research Institute, Pamplona, Spain.
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879 https://www.grid.ac/institutes/grid.413448.e schema:alternateName Instituto de Salud Carlos III
880 schema:name CIBERobn Physiopathology of Obesity and Nutrition, Centre of Biomedical Research Network, ISCIII, Madrid, Spain.
881 Department of Nutrition, Food Science and Physiology/Centre for Nutrition Research, University of Navarra, Edificio de Investigación, calle de Irunlarrea 1, Pamplona 31008, Navarra, Spain.
882 IDISNA Navarra's Health Research Institute, Pamplona, Spain.
883 rdf:type schema:Organization
884 https://www.grid.ac/institutes/grid.416709.d schema:alternateName Sumitomo Hospital
885 schema:name Department of Endocrinology and Metabolism, Sumitomo Hospital, Osaka, Japan.
886 rdf:type schema:Organization
887 https://www.grid.ac/institutes/grid.482878.9 schema:alternateName IMDEA Food
888 schema:name CIBERobn Physiopathology of Obesity and Nutrition, Centre of Biomedical Research Network, ISCIII, Madrid, Spain.
889 Department of Nutrition, Food Science and Physiology/Centre for Nutrition Research, University of Navarra, Edificio de Investigación, calle de Irunlarrea 1, Pamplona 31008, Navarra, Spain.
890 IDISNA Navarra's Health Research Institute, Pamplona, Spain.
891 IMDEA Food Institute, Madrid, Spain.
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893 https://www.grid.ac/institutes/grid.59734.3c schema:alternateName Icahn School of Medicine at Mount Sinai
894 schema:name Charles Bronfman Institute for Personalized Medicine, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
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896 https://www.grid.ac/institutes/grid.64337.35 schema:alternateName Louisiana State University
897 schema:name Pennington Biomedical Research Center/LSU, Baton Rouge, Louisiana, USA.
898 rdf:type schema:Organization
 




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