Metabonomics: a platform for studying drug toxicity and gene function View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-02

AUTHORS

Jeremy K Nicholson, John Connelly, John C Lindon, Elaine Holmes

ABSTRACT

The later that a molecule or molecular class is lost from the drug development pipeline, the higher the financial cost. Minimizing attrition is therefore one of the most important aims of a pharmaceutical discovery programme. Novel technologies that increase the probability of making the right choice early save resources, and promote safety, efficacy and profitability. Metabonomics is a systems approach for studying in vivo metabolic profiles, which promises to provide information on drug toxicity, disease processes and gene function at several stages in the discovery-and-development process. More... »

PAGES

153-161

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nrd728

DOI

http://dx.doi.org/10.1038/nrd728

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1030526247

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12120097


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