En route to improved treatment options View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-01-08

AUTHORS

Heiko Becker, Clara D. Bloomfield

ABSTRACT

Progress was made in major aspects of acute myeloid leukaemia in 2012. Gemtuzumab ozogamicin and decitabine were shown to improve outcomes, relapse after stem-cell transplantation might be prevented by selecting donors according to their KIR genotypes, and next-generation sequencing has provided insights into mutational patterns and disease evolution.

PAGES

76-79

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nrclinonc.2012.239

DOI

http://dx.doi.org/10.1038/nrclinonc.2012.239

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013632881

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23296115


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Combined Modality Therapy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Leukemia, Myeloid, Acute", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Targeted Therapy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Hematology and Oncology, University of Freiburg Medical Center, Hugstetter Strasse 55, 79106, Freiburg, Germany", 
          "id": "http://www.grid.ac/institutes/grid.7708.8", 
          "name": [
            "Department of Hematology and Oncology, University of Freiburg Medical Center, Hugstetter Strasse 55, 79106, Freiburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Becker", 
        "givenName": "Heiko", 
        "id": "sg:person.0631556757.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631556757.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Ohio State University Comprehensive Cancer Center, 1216 James Cancer Hospital, 300 West 10th Avenue, 43210, Columbus, OH, USA", 
          "id": "http://www.grid.ac/institutes/grid.413944.f", 
          "name": [
            "The Ohio State University Comprehensive Cancer Center, 1216 James Cancer Hospital, 300 West 10th Avenue, 43210, Columbus, OH, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bloomfield", 
        "givenName": "Clara D.", 
        "id": "sg:person.01146147326.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146147326.32"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2013-01-08", 
    "datePublishedReg": "2013-01-08", 
    "description": "Progress was made in major aspects of acute myeloid leukaemia in 2012. Gemtuzumab ozogamicin and decitabine were shown to improve outcomes, relapse after stem-cell transplantation might be prevented by selecting donors according to their KIR genotypes, and next-generation sequencing has provided insights into mutational patterns and disease evolution.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/nrclinonc.2012.239", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1034153", 
        "issn": [
          "1759-4774", 
          "1759-4782"
        ], 
        "name": "Nature Reviews Clinical Oncology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "10"
      }
    ], 
    "keywords": [
      "stem cell transplantation", 
      "acute myeloid leukemia", 
      "gemtuzumab ozogamicin", 
      "treatment options", 
      "myeloid leukemia", 
      "KIR genotype", 
      "disease evolution", 
      "next-generation sequencing", 
      "mutational patterns", 
      "ozogamicin", 
      "transplantation", 
      "leukemia", 
      "decitabine", 
      "outcomes", 
      "options", 
      "donors", 
      "genotypes", 
      "sequencing", 
      "patterns", 
      "major aspects", 
      "progress", 
      "route", 
      "aspects", 
      "insights", 
      "evolution"
    ], 
    "name": "En route to improved treatment options", 
    "pagination": "76-79", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1013632881"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nrclinonc.2012.239"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "23296115"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nrclinonc.2012.239", 
      "https://app.dimensions.ai/details/publication/pub.1013632881"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:31", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_605.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/nrclinonc.2012.239"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nrclinonc.2012.239'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nrclinonc.2012.239'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nrclinonc.2012.239'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nrclinonc.2012.239'


 

This table displays all metadata directly associated to this object as RDF triples.

116 TRIPLES      20 PREDICATES      55 URIs      47 LITERALS      12 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nrclinonc.2012.239 schema:about N2244dca715f74116a586ae96189370b8
2 N337de1827486402db92e4d3324e03a5f
3 N420f8db0e12a452f8bef6ed73f2285a2
4 N9caf9eabfc404660883ab9badb83b2a7
5 Nf3670809221148739bd16b71d77b40ea
6 anzsrc-for:11
7 anzsrc-for:1102
8 schema:author Nd3814a691b4a4554998cfd3171b1c49d
9 schema:datePublished 2013-01-08
10 schema:datePublishedReg 2013-01-08
11 schema:description Progress was made in major aspects of acute myeloid leukaemia in 2012. Gemtuzumab ozogamicin and decitabine were shown to improve outcomes, relapse after stem-cell transplantation might be prevented by selecting donors according to their KIR genotypes, and next-generation sequencing has provided insights into mutational patterns and disease evolution.
12 schema:genre article
13 schema:isAccessibleForFree false
14 schema:isPartOf N006ecc1327ef4b2fb6f4fe879286f6c7
15 N43bc5feefb7f45309fc867a8b4ae772e
16 sg:journal.1034153
17 schema:keywords KIR genotype
18 acute myeloid leukemia
19 aspects
20 decitabine
21 disease evolution
22 donors
23 evolution
24 gemtuzumab ozogamicin
25 genotypes
26 insights
27 leukemia
28 major aspects
29 mutational patterns
30 myeloid leukemia
31 next-generation sequencing
32 options
33 outcomes
34 ozogamicin
35 patterns
36 progress
37 route
38 sequencing
39 stem cell transplantation
40 transplantation
41 treatment options
42 schema:name En route to improved treatment options
43 schema:pagination 76-79
44 schema:productId N3639393cb9c44ee0b1760d7bf177e0a4
45 Nb3d924480e344bce9094bda711f8b66e
46 Nd425ff54422c489cbe23009a4cd055ad
47 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013632881
48 https://doi.org/10.1038/nrclinonc.2012.239
49 schema:sdDatePublished 2022-12-01T06:31
50 schema:sdLicense https://scigraph.springernature.com/explorer/license/
51 schema:sdPublisher Ne28677ceb7a9475b8345aad8f62f52a3
52 schema:url https://doi.org/10.1038/nrclinonc.2012.239
53 sgo:license sg:explorer/license/
54 sgo:sdDataset articles
55 rdf:type schema:ScholarlyArticle
56 N006ecc1327ef4b2fb6f4fe879286f6c7 schema:volumeNumber 10
57 rdf:type schema:PublicationVolume
58 N2244dca715f74116a586ae96189370b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
59 schema:name Time Factors
60 rdf:type schema:DefinedTerm
61 N337de1827486402db92e4d3324e03a5f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
62 schema:name Humans
63 rdf:type schema:DefinedTerm
64 N3639393cb9c44ee0b1760d7bf177e0a4 schema:name doi
65 schema:value 10.1038/nrclinonc.2012.239
66 rdf:type schema:PropertyValue
67 N420f8db0e12a452f8bef6ed73f2285a2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
68 schema:name Leukemia, Myeloid, Acute
69 rdf:type schema:DefinedTerm
70 N43bc5feefb7f45309fc867a8b4ae772e schema:issueNumber 2
71 rdf:type schema:PublicationIssue
72 N572ef399c2944a41b4dea4a6199744fd rdf:first sg:person.01146147326.32
73 rdf:rest rdf:nil
74 N9caf9eabfc404660883ab9badb83b2a7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Molecular Targeted Therapy
76 rdf:type schema:DefinedTerm
77 Nb3d924480e344bce9094bda711f8b66e schema:name pubmed_id
78 schema:value 23296115
79 rdf:type schema:PropertyValue
80 Nd3814a691b4a4554998cfd3171b1c49d rdf:first sg:person.0631556757.06
81 rdf:rest N572ef399c2944a41b4dea4a6199744fd
82 Nd425ff54422c489cbe23009a4cd055ad schema:name dimensions_id
83 schema:value pub.1013632881
84 rdf:type schema:PropertyValue
85 Ne28677ceb7a9475b8345aad8f62f52a3 schema:name Springer Nature - SN SciGraph project
86 rdf:type schema:Organization
87 Nf3670809221148739bd16b71d77b40ea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Combined Modality Therapy
89 rdf:type schema:DefinedTerm
90 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
91 schema:name Medical and Health Sciences
92 rdf:type schema:DefinedTerm
93 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
94 schema:name Cardiorespiratory Medicine and Haematology
95 rdf:type schema:DefinedTerm
96 sg:journal.1034153 schema:issn 1759-4774
97 1759-4782
98 schema:name Nature Reviews Clinical Oncology
99 schema:publisher Springer Nature
100 rdf:type schema:Periodical
101 sg:person.01146147326.32 schema:affiliation grid-institutes:grid.413944.f
102 schema:familyName Bloomfield
103 schema:givenName Clara D.
104 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146147326.32
105 rdf:type schema:Person
106 sg:person.0631556757.06 schema:affiliation grid-institutes:grid.7708.8
107 schema:familyName Becker
108 schema:givenName Heiko
109 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631556757.06
110 rdf:type schema:Person
111 grid-institutes:grid.413944.f schema:alternateName The Ohio State University Comprehensive Cancer Center, 1216 James Cancer Hospital, 300 West 10th Avenue, 43210, Columbus, OH, USA
112 schema:name The Ohio State University Comprehensive Cancer Center, 1216 James Cancer Hospital, 300 West 10th Avenue, 43210, Columbus, OH, USA
113 rdf:type schema:Organization
114 grid-institutes:grid.7708.8 schema:alternateName Department of Hematology and Oncology, University of Freiburg Medical Center, Hugstetter Strasse 55, 79106, Freiburg, Germany
115 schema:name Department of Hematology and Oncology, University of Freiburg Medical Center, Hugstetter Strasse 55, 79106, Freiburg, Germany
116 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...