Is there still a role for SPECT–CT in oncology in the PET–CT era? View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-12

AUTHORS

Rodney J. Hicks, Michael S. Hofman

ABSTRACT

For the evaluation of biological processes using radioisotopes, there are two competing technologies: single-photon emission computed tomography (SPECT) and positron emission tomography (PET). Both are tomographic techniques that enable 3D localization and can be combined with CT for hybrid imaging. PET-CT has clear technical superiority including superior resolution, speed and quantitative capability. SPECT-CT currently has greater accessibility, lower cost and availability of a wider range of approved radiotracers. However, the past decade has seen dramatic growth in PET-CT with decreasing costs and development of an increasing array of PET tracers that can substitute existing SPECT applications. PET-CT is also changing the paradigm of imaging from lesion measurement to lesion characterization and target quantification, supporting a new era of personalized cancer therapy. The efficiency and cost savings associated with improved diagnosis and clinical decision-making provided by PET-CT make a cogent argument for it becoming the dominant molecular technique in oncology. More... »

PAGES

712

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrclinonc.2012.188

    DOI

    http://dx.doi.org/10.1038/nrclinonc.2012.188

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1007357547

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/23149896


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