Reverse remodelling and myocardial recovery in heart failure View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-09-21

AUTHORS

Gene H. Kim, Nir Uriel, Daniel Burkhoff

ABSTRACT

Advances in medical and device therapies have demonstrated the capacity of the heart to reverse the failing phenotype. The development of normative changes to ventricular size and function led to the concept of reverse remodelling. Among heart failure therapies, durable mechanical circulatory support is most consistently associated with the largest degree of reverse remodelling. Accordingly, research to analyse human tissue after a period of mechanical circulatory support continues to yield a wealth of information. In this Review, we summarize the latest findings on reverse remodelling and myocardial recovery. Accumulating evidence shows that the molecular changes associated with heart failure, in particular in the transcriptome, metabalome, and extracellular matrix, persist in the reverse-remodelled myocardium despite apparent normalization of macrolevel properties. Therefore, reverse remodelling should be distinguished from true myocardial recovery, in which a failing heart regains both normal function and molecular makeup. These findings have implications for future research to develop therapies to repair fully the failing myocardium. Meanwhile, recognition by society guidelines of this new clinical phenotype, which is coming to be known as a state of heart failure remission, underscores the need to accurately define and identify reverse modelled myocardium for the establishment of appropriate therapies. More... »

PAGES

83-96

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nrcardio.2017.139

DOI

http://dx.doi.org/10.1038/nrcardio.2017.139

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091879673

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28933783


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Department of Medicine, Division of Cardiology, University of Chicago, 5841 S. Maryland Avenue, Chicago, Illinois 60637, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Gene H.", 
        "id": "sg:person.01230440325.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01230440325.64"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Medicine, Division of Cardiology, University of Chicago, 5841 S. Maryland Avenue, Chicago, Illinois 60637, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Uriel", 
        "givenName": "Nir", 
        "id": "sg:person.01160447235.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01160447235.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cardiovascular Research Foundation", 
          "id": "https://www.grid.ac/institutes/grid.418668.5", 
          "name": [
            "Cardiovascular Research Foundation and Division of Cardiology, Columbia University Medical Center/New York-Presbyterian Hospital, 1900 Broadway 9th Floor, New York, New York 10019, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Burkhoff", 
        "givenName": "Daniel", 
        "id": "sg:person.0746257355.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746257355.45"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1161/circheartfailure.113.000813", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000079538"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circheartfailure.113.000813", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000079538"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circheartfailure.113.000813", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000079538"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/physrev.00012.2007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000377503"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/cir.0b013e31829e8807", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000825420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/cir.0b013e31829e8807", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000825420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.106.633180", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001451290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1610426", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002058072"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nri3800", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002078463", 
          "https://doi.org/10.1038/nri3800"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2012.06.062", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002206813"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcmg.2010.09.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002304889"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/jaha.114.000570", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003303865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.healun.2015.06.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004242026"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jamacardio.2016.0208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004855809"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jamacardio.2016.0208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004855809"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jamacardio.2016.0208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004855809"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.65.7.1446", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004898897"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa053063", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004923944"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.trsl.2016.02.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005271854"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2006.10.071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005902235"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11897-013-0157-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006162218", 
          "https://doi.org/10.1007/s11897-013-0157-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.yjmcc.2016.01.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006550937"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cbpa.2006.09.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006864659"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0735-1097(01)01268-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008074659"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.114.010194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008076530"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.114.010194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008076530"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1512913", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008600438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0735-1097(99)00630-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008654840"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cardfail.2005.10.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008936979"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.healun.2016.01.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008994083"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0735-1097(94)00543-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009694660"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.115.017545", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009844535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.115.017545", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009844535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10741-007-9034-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010967205", 
          "https://doi.org/10.1007/s10741-007-9034-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10741-007-9034-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010967205", 
          "https://doi.org/10.1007/s10741-007-9034-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2010.11.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011114371"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pcad.2016.01.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011124194"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.111.040071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011221470"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1312808", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011945742"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.107.702795", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012072235"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/aor.12151", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013644123"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mtc.2001.112632", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013713322"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0735-1097(00)01006-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013996144"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1401724111", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014675894"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.108.813576", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017096898"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacbts.2016.04.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017917651"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacbts.2016.06.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019250536"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circresaha.114.303915", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019735315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circresaha.114.303915", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019735315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cardfail.2011.03.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021319074"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.115.017355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021914264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.115.017355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021914264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cardfail.2015.08.342", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022312533"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.healun.2015.08.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022403222"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(09)60692-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022799634"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.healun.2006.05.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022840529"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.113.006855", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023122892"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.113.006855", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023122892"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.102.22.2713", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023439502"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2008.04.036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023647495"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0002-9149(82)90035-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024197321"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2016.07.743", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025361435"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/17434440.2016.1243053", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025835238"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circresaha.111.249433", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026061889"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circresaha.111.249433", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026061889"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.113.003863", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026231671"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.113.003863", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026231671"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa032423", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029389171"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/ehs257", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029901177"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1110186", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031030718"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.104.515106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031493784"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2004.11.042", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031896409"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002480-198907000-00086", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032168518"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002480-198907000-00086", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032168518"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.104.520817", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033236821"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ejhf.673", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038066406"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1053-2498(99)00071-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038137535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.103.20.2441", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039059540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02058586", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039118000", 
          "https://doi.org/10.1007/bf02058586"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02058586", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039118000", 
          "https://doi.org/10.1007/bf02058586"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/crd.0000000000000068", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039191043"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/crd.0000000000000068", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039191043"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/crd.0000000000000068", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039191043"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.echo.2016.06.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039633275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa050496", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040663463"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2016.07.718", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040675252"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci.insight.86038", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042208265"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.yjmcc.2016.01.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042430360"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/hc0402.102623", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043456182"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacbts.2016.05.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044121568"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.109.933960", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044967961"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.102.16.1944", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045534907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/hc3101.093903", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046426930"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2011.08.041", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049528204"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cphy.c140045", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051768948"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.res.0000159390.03503.c3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053184914"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.res.0000159390.03503.c3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053184914"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/jaha.114.001504", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053618785"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/physiolgenomics.00004.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053626676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.91.11.2717", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063335916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.116.023686", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063344627"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.116.023686", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063344627"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077112588", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpheart.1991.260.5.h1406", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078139645"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circresaha.116.310174", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079396737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circresaha.116.310174", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079396737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082227567", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ajh/7.9.106s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082522105"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083234244", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcmg.2016.12.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084804974"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2017.06.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090577993"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-09-21", 
    "datePublishedReg": "2017-09-21", 
    "description": "Advances in medical and device therapies have demonstrated the capacity of the heart to reverse the failing phenotype. The development of normative changes to ventricular size and function led to the concept of reverse remodelling. Among heart failure therapies, durable mechanical circulatory support is most consistently associated with the largest degree of reverse remodelling. Accordingly, research to analyse human tissue after a period of mechanical circulatory support continues to yield a wealth of information. In this Review, we summarize the latest findings on reverse remodelling and myocardial recovery. Accumulating evidence shows that the molecular changes associated with heart failure, in particular in the transcriptome, metabalome, and extracellular matrix, persist in the reverse-remodelled myocardium despite apparent normalization of macrolevel properties. Therefore, reverse remodelling should be distinguished from true myocardial recovery, in which a failing heart regains both normal function and molecular makeup. These findings have implications for future research to develop therapies to repair fully the failing myocardium. Meanwhile, recognition by society guidelines of this new clinical phenotype, which is coming to be known as a state of heart failure remission, underscores the need to accurately define and identify reverse modelled myocardium for the establishment of appropriate therapies.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/nrcardio.2017.139", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1345537", 
        "issn": [
          "1423-5528", 
          "1662-629X"
        ], 
        "name": "Nature Reviews Cardiology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "15"
      }
    ], 
    "name": "Reverse remodelling and myocardial recovery in heart failure", 
    "pagination": "83-96", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "60149e3587a2258eff86aaa92f820dae7da7246154408132e53b1743f68a2400"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28933783"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101500075"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nrcardio.2017.139"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1091879673"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nrcardio.2017.139", 
      "https://app.dimensions.ai/details/publication/pub.1091879673"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T01:47", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8700_00000427.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/nrcardio.2017.139"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nrcardio.2017.139'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nrcardio.2017.139'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nrcardio.2017.139'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nrcardio.2017.139'


 

This table displays all metadata directly associated to this object as RDF triples.

361 TRIPLES      21 PREDICATES      119 URIs      20 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nrcardio.2017.139 schema:about anzsrc-for:11
2 anzsrc-for:1102
3 schema:author N2d7ec844a8e84b10bfa1286d30abde4a
4 schema:citation sg:pub.10.1007/bf02058586
5 sg:pub.10.1007/s10741-007-9034-1
6 sg:pub.10.1007/s11897-013-0157-5
7 sg:pub.10.1038/nri3800
8 https://app.dimensions.ai/details/publication/pub.1077112588
9 https://app.dimensions.ai/details/publication/pub.1082227567
10 https://app.dimensions.ai/details/publication/pub.1083234244
11 https://doi.org/10.1001/jamacardio.2016.0208
12 https://doi.org/10.1002/cphy.c140045
13 https://doi.org/10.1002/ejhf.673
14 https://doi.org/10.1016/0002-9149(82)90035-2
15 https://doi.org/10.1016/0735-1097(94)00543-y
16 https://doi.org/10.1016/j.cardfail.2005.10.012
17 https://doi.org/10.1016/j.cardfail.2011.03.005
18 https://doi.org/10.1016/j.cardfail.2015.08.342
19 https://doi.org/10.1016/j.cbpa.2006.09.014
20 https://doi.org/10.1016/j.echo.2016.06.009
21 https://doi.org/10.1016/j.healun.2006.05.011
22 https://doi.org/10.1016/j.healun.2015.06.015
23 https://doi.org/10.1016/j.healun.2015.08.004
24 https://doi.org/10.1016/j.healun.2016.01.001
25 https://doi.org/10.1016/j.jacbts.2016.04.006
26 https://doi.org/10.1016/j.jacbts.2016.05.005
27 https://doi.org/10.1016/j.jacbts.2016.06.009
28 https://doi.org/10.1016/j.jacc.2004.11.042
29 https://doi.org/10.1016/j.jacc.2006.10.071
30 https://doi.org/10.1016/j.jacc.2008.04.036
31 https://doi.org/10.1016/j.jacc.2010.11.010
32 https://doi.org/10.1016/j.jacc.2011.08.041
33 https://doi.org/10.1016/j.jacc.2012.06.062
34 https://doi.org/10.1016/j.jacc.2016.07.718
35 https://doi.org/10.1016/j.jacc.2016.07.743
36 https://doi.org/10.1016/j.jacc.2017.06.001
37 https://doi.org/10.1016/j.jcmg.2010.09.021
38 https://doi.org/10.1016/j.jcmg.2016.12.019
39 https://doi.org/10.1016/j.pcad.2016.01.003
40 https://doi.org/10.1016/j.trsl.2016.02.006
41 https://doi.org/10.1016/j.yjmcc.2016.01.008
42 https://doi.org/10.1016/j.yjmcc.2016.01.011
43 https://doi.org/10.1016/s0140-6736(09)60692-9
44 https://doi.org/10.1016/s0735-1097(00)01006-8
45 https://doi.org/10.1016/s0735-1097(01)01268-2
46 https://doi.org/10.1016/s0735-1097(99)00630-0
47 https://doi.org/10.1016/s1053-2498(99)00071-6
48 https://doi.org/10.1056/nejmoa032423
49 https://doi.org/10.1056/nejmoa050496
50 https://doi.org/10.1056/nejmoa053063
51 https://doi.org/10.1056/nejmoa1110186
52 https://doi.org/10.1056/nejmoa1312808
53 https://doi.org/10.1056/nejmoa1512913
54 https://doi.org/10.1056/nejmoa1610426
55 https://doi.org/10.1067/mtc.2001.112632
56 https://doi.org/10.1073/pnas.1401724111
57 https://doi.org/10.1080/17434440.2016.1243053
58 https://doi.org/10.1093/ajh/7.9.106s
59 https://doi.org/10.1093/eurheartj/ehs257
60 https://doi.org/10.1097/00002480-198907000-00086
61 https://doi.org/10.1097/crd.0000000000000068
62 https://doi.org/10.1111/aor.12151
63 https://doi.org/10.1152/ajpheart.1991.260.5.h1406
64 https://doi.org/10.1152/physiolgenomics.00004.2004
65 https://doi.org/10.1152/physrev.00012.2007
66 https://doi.org/10.1161/01.cir.102.16.1944
67 https://doi.org/10.1161/01.cir.102.22.2713
68 https://doi.org/10.1161/01.cir.103.20.2441
69 https://doi.org/10.1161/01.cir.65.7.1446
70 https://doi.org/10.1161/01.cir.91.11.2717
71 https://doi.org/10.1161/01.res.0000159390.03503.c3
72 https://doi.org/10.1161/cir.0b013e31829e8807
73 https://doi.org/10.1161/circheartfailure.113.000813
74 https://doi.org/10.1161/circresaha.111.249433
75 https://doi.org/10.1161/circresaha.114.303915
76 https://doi.org/10.1161/circresaha.116.310174
77 https://doi.org/10.1161/circulationaha.104.515106
78 https://doi.org/10.1161/circulationaha.104.520817
79 https://doi.org/10.1161/circulationaha.106.633180
80 https://doi.org/10.1161/circulationaha.107.702795
81 https://doi.org/10.1161/circulationaha.108.813576
82 https://doi.org/10.1161/circulationaha.109.933960
83 https://doi.org/10.1161/circulationaha.111.040071
84 https://doi.org/10.1161/circulationaha.113.003863
85 https://doi.org/10.1161/circulationaha.113.006855
86 https://doi.org/10.1161/circulationaha.114.010194
87 https://doi.org/10.1161/circulationaha.115.017355
88 https://doi.org/10.1161/circulationaha.115.017545
89 https://doi.org/10.1161/circulationaha.116.023686
90 https://doi.org/10.1161/hc0402.102623
91 https://doi.org/10.1161/hc3101.093903
92 https://doi.org/10.1161/jaha.114.000570
93 https://doi.org/10.1161/jaha.114.001504
94 https://doi.org/10.1172/jci.insight.86038
95 schema:datePublished 2017-09-21
96 schema:datePublishedReg 2017-09-21
97 schema:description Advances in medical and device therapies have demonstrated the capacity of the heart to reverse the failing phenotype. The development of normative changes to ventricular size and function led to the concept of reverse remodelling. Among heart failure therapies, durable mechanical circulatory support is most consistently associated with the largest degree of reverse remodelling. Accordingly, research to analyse human tissue after a period of mechanical circulatory support continues to yield a wealth of information. In this Review, we summarize the latest findings on reverse remodelling and myocardial recovery. Accumulating evidence shows that the molecular changes associated with heart failure, in particular in the transcriptome, metabalome, and extracellular matrix, persist in the reverse-remodelled myocardium despite apparent normalization of macrolevel properties. Therefore, reverse remodelling should be distinguished from true myocardial recovery, in which a failing heart regains both normal function and molecular makeup. These findings have implications for future research to develop therapies to repair fully the failing myocardium. Meanwhile, recognition by society guidelines of this new clinical phenotype, which is coming to be known as a state of heart failure remission, underscores the need to accurately define and identify reverse modelled myocardium for the establishment of appropriate therapies.
98 schema:genre research_article
99 schema:inLanguage en
100 schema:isAccessibleForFree false
101 schema:isPartOf Na1c6c209c0db44848886ffbb9f85644d
102 Ne7ee3eb9f4eb4dec84f9adc6de13c709
103 sg:journal.1345537
104 schema:name Reverse remodelling and myocardial recovery in heart failure
105 schema:pagination 83-96
106 schema:productId N05af336553024815b9038ee02a602812
107 N122dee74292d449e8bf9becbd89f4ed9
108 Na8b153a14023444a9957f9e0e7ee9df7
109 Nc4b7b44c26344eddb01e9b3f003347bd
110 Nc6cc6f19ed84468a9e43eb9d73edd6b8
111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091879673
112 https://doi.org/10.1038/nrcardio.2017.139
113 schema:sdDatePublished 2019-04-11T01:47
114 schema:sdLicense https://scigraph.springernature.com/explorer/license/
115 schema:sdPublisher Nfd7c492d0611414aa24ac63869122a2c
116 schema:url https://www.nature.com/articles/nrcardio.2017.139
117 sgo:license sg:explorer/license/
118 sgo:sdDataset articles
119 rdf:type schema:ScholarlyArticle
120 N05af336553024815b9038ee02a602812 schema:name dimensions_id
121 schema:value pub.1091879673
122 rdf:type schema:PropertyValue
123 N122dee74292d449e8bf9becbd89f4ed9 schema:name doi
124 schema:value 10.1038/nrcardio.2017.139
125 rdf:type schema:PropertyValue
126 N2d7ec844a8e84b10bfa1286d30abde4a rdf:first sg:person.01230440325.64
127 rdf:rest Nd51534078cdb4529be5104d4c97a51f5
128 N3b644c0b02b44eabbbf239a4135b6456 schema:name Department of Medicine, Division of Cardiology, University of Chicago, 5841 S. Maryland Avenue, Chicago, Illinois 60637, USA.
129 rdf:type schema:Organization
130 N6d6d399340e24b63879f8440ea184247 schema:name Department of Medicine, Division of Cardiology, University of Chicago, 5841 S. Maryland Avenue, Chicago, Illinois 60637, USA.
131 rdf:type schema:Organization
132 N8d7fb5f81f1e4bc2bc2c52e4ee022f67 rdf:first sg:person.0746257355.45
133 rdf:rest rdf:nil
134 Na1c6c209c0db44848886ffbb9f85644d schema:issueNumber 2
135 rdf:type schema:PublicationIssue
136 Na8b153a14023444a9957f9e0e7ee9df7 schema:name nlm_unique_id
137 schema:value 101500075
138 rdf:type schema:PropertyValue
139 Nc4b7b44c26344eddb01e9b3f003347bd schema:name pubmed_id
140 schema:value 28933783
141 rdf:type schema:PropertyValue
142 Nc6cc6f19ed84468a9e43eb9d73edd6b8 schema:name readcube_id
143 schema:value 60149e3587a2258eff86aaa92f820dae7da7246154408132e53b1743f68a2400
144 rdf:type schema:PropertyValue
145 Nd51534078cdb4529be5104d4c97a51f5 rdf:first sg:person.01160447235.53
146 rdf:rest N8d7fb5f81f1e4bc2bc2c52e4ee022f67
147 Ne7ee3eb9f4eb4dec84f9adc6de13c709 schema:volumeNumber 15
148 rdf:type schema:PublicationVolume
149 Nfd7c492d0611414aa24ac63869122a2c schema:name Springer Nature - SN SciGraph project
150 rdf:type schema:Organization
151 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
152 schema:name Medical and Health Sciences
153 rdf:type schema:DefinedTerm
154 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
155 schema:name Cardiorespiratory Medicine and Haematology
156 rdf:type schema:DefinedTerm
157 sg:journal.1345537 schema:issn 1423-5528
158 1662-629X
159 schema:name Nature Reviews Cardiology
160 rdf:type schema:Periodical
161 sg:person.01160447235.53 schema:affiliation N6d6d399340e24b63879f8440ea184247
162 schema:familyName Uriel
163 schema:givenName Nir
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01160447235.53
165 rdf:type schema:Person
166 sg:person.01230440325.64 schema:affiliation N3b644c0b02b44eabbbf239a4135b6456
167 schema:familyName Kim
168 schema:givenName Gene H.
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01230440325.64
170 rdf:type schema:Person
171 sg:person.0746257355.45 schema:affiliation https://www.grid.ac/institutes/grid.418668.5
172 schema:familyName Burkhoff
173 schema:givenName Daniel
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746257355.45
175 rdf:type schema:Person
176 sg:pub.10.1007/bf02058586 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039118000
177 https://doi.org/10.1007/bf02058586
178 rdf:type schema:CreativeWork
179 sg:pub.10.1007/s10741-007-9034-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010967205
180 https://doi.org/10.1007/s10741-007-9034-1
181 rdf:type schema:CreativeWork
182 sg:pub.10.1007/s11897-013-0157-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006162218
183 https://doi.org/10.1007/s11897-013-0157-5
184 rdf:type schema:CreativeWork
185 sg:pub.10.1038/nri3800 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002078463
186 https://doi.org/10.1038/nri3800
187 rdf:type schema:CreativeWork
188 https://app.dimensions.ai/details/publication/pub.1077112588 schema:CreativeWork
189 https://app.dimensions.ai/details/publication/pub.1082227567 schema:CreativeWork
190 https://app.dimensions.ai/details/publication/pub.1083234244 schema:CreativeWork
191 https://doi.org/10.1001/jamacardio.2016.0208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004855809
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1002/cphy.c140045 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051768948
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1002/ejhf.673 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038066406
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1016/0002-9149(82)90035-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024197321
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1016/0735-1097(94)00543-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1009694660
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1016/j.cardfail.2005.10.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008936979
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1016/j.cardfail.2011.03.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021319074
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1016/j.cardfail.2015.08.342 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022312533
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1016/j.cbpa.2006.09.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006864659
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1016/j.echo.2016.06.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039633275
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1016/j.healun.2006.05.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022840529
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1016/j.healun.2015.06.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004242026
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1016/j.healun.2015.08.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022403222
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1016/j.healun.2016.01.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008994083
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1016/j.jacbts.2016.04.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017917651
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1016/j.jacbts.2016.05.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044121568
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1016/j.jacbts.2016.06.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019250536
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1016/j.jacc.2004.11.042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031896409
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1016/j.jacc.2006.10.071 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005902235
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1016/j.jacc.2008.04.036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023647495
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1016/j.jacc.2010.11.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011114371
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1016/j.jacc.2011.08.041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049528204
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1016/j.jacc.2012.06.062 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002206813
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1016/j.jacc.2016.07.718 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040675252
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1016/j.jacc.2016.07.743 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025361435
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1016/j.jacc.2017.06.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090577993
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1016/j.jcmg.2010.09.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002304889
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1016/j.jcmg.2016.12.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084804974
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1016/j.pcad.2016.01.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011124194
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1016/j.trsl.2016.02.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005271854
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1016/j.yjmcc.2016.01.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042430360
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1016/j.yjmcc.2016.01.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006550937
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1016/s0140-6736(09)60692-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022799634
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1016/s0735-1097(00)01006-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013996144
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1016/s0735-1097(01)01268-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008074659
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1016/s0735-1097(99)00630-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008654840
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1016/s1053-2498(99)00071-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038137535
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1056/nejmoa032423 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029389171
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1056/nejmoa050496 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040663463
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1056/nejmoa053063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004923944
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1056/nejmoa1110186 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031030718
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1056/nejmoa1312808 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011945742
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1056/nejmoa1512913 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008600438
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1056/nejmoa1610426 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002058072
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1067/mtc.2001.112632 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013713322
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1073/pnas.1401724111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014675894
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1080/17434440.2016.1243053 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025835238
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1093/ajh/7.9.106s schema:sameAs https://app.dimensions.ai/details/publication/pub.1082522105
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1093/eurheartj/ehs257 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029901177
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1097/00002480-198907000-00086 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032168518
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1097/crd.0000000000000068 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039191043
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1111/aor.12151 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013644123
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1152/ajpheart.1991.260.5.h1406 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078139645
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1152/physiolgenomics.00004.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053626676
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1152/physrev.00012.2007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000377503
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1161/01.cir.102.16.1944 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045534907
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1161/01.cir.102.22.2713 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023439502
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1161/01.cir.103.20.2441 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039059540
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1161/01.cir.65.7.1446 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004898897
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1161/01.cir.91.11.2717 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063335916
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1161/01.res.0000159390.03503.c3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053184914
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1161/cir.0b013e31829e8807 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000825420
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1161/circheartfailure.113.000813 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000079538
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1161/circresaha.111.249433 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026061889
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1161/circresaha.114.303915 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019735315
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1161/circresaha.116.310174 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079396737
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1161/circulationaha.104.515106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031493784
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1161/circulationaha.104.520817 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033236821
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1161/circulationaha.106.633180 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001451290
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1161/circulationaha.107.702795 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012072235
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1161/circulationaha.108.813576 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017096898
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1161/circulationaha.109.933960 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044967961
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1161/circulationaha.111.040071 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011221470
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1161/circulationaha.113.003863 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026231671
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1161/circulationaha.113.006855 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023122892
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1161/circulationaha.114.010194 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008076530
342 rdf:type schema:CreativeWork
343 https://doi.org/10.1161/circulationaha.115.017355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021914264
344 rdf:type schema:CreativeWork
345 https://doi.org/10.1161/circulationaha.115.017545 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009844535
346 rdf:type schema:CreativeWork
347 https://doi.org/10.1161/circulationaha.116.023686 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063344627
348 rdf:type schema:CreativeWork
349 https://doi.org/10.1161/hc0402.102623 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043456182
350 rdf:type schema:CreativeWork
351 https://doi.org/10.1161/hc3101.093903 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046426930
352 rdf:type schema:CreativeWork
353 https://doi.org/10.1161/jaha.114.000570 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003303865
354 rdf:type schema:CreativeWork
355 https://doi.org/10.1161/jaha.114.001504 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053618785
356 rdf:type schema:CreativeWork
357 https://doi.org/10.1172/jci.insight.86038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042208265
358 rdf:type schema:CreativeWork
359 https://www.grid.ac/institutes/grid.418668.5 schema:alternateName Cardiovascular Research Foundation
360 schema:name Cardiovascular Research Foundation and Division of Cardiology, Columbia University Medical Center/New York-Presbyterian Hospital, 1900 Broadway 9th Floor, New York, New York 10019, USA.
361 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...