Papillomaviruses and cancer: from basic studies to clinical application View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-05

AUTHORS

Harald zur Hausen

ABSTRACT

Links between human papillomaviruses (HPVs) and cervical cancer were first suspected almost 30 years ago. DNA of specific HPV types has since been found in almost all cervical cancer biopsies. HPV oncogenes that are expressed in these cells are involved in their transformation and immortalization, and are required for the progression towards malignancy. Epidemiological studies have underlined that HPVs are the main aetiological factor for cervical cancer. But how has this knowledge been translated into the clinic to allow the prevention, screening and treatment of cervical cancer? More... »

PAGES

342-350

Journal

TITLE

Nature Reviews Cancer

ISSUE

5

VOLUME

2

Author Affiliations

Related Patents

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nrc798

DOI

http://dx.doi.org/10.1038/nrc798

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1030753299

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12044010


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