Hypoxia — a key regulatory factor in tumour growth View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-01

AUTHORS

Adrian L Harris

ABSTRACT

Cells undergo a variety of biological responses when placed in hypoxic conditions, including activation of signalling pathways that regulate proliferation, angiogenesis and death. Cancer cells have adapted these pathways, allowing tumours to survive and even grow under hypoxic conditions, and tumour hypoxia is associated with poor prognosis and resistance to radiation therapy. Many elements of the hypoxia-response pathway are therefore good candidates for therapeutic targeting. More... »

PAGES

38-47

References to SciGraph publications

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  • Journal

    TITLE

    Nature Reviews Cancer

    ISSUE

    1

    VOLUME

    2

    Author Affiliations

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrc704

    DOI

    http://dx.doi.org/10.1038/nrc704

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1028740665

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/11902584


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    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nrc704'

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    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nrc704'

    RDF/XML is a standard XML format for linked data.

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